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Molly K Imgruet
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Journal Articles

Combined Deficiency of Chromosome 7 Myeloid Tumor Suppressors Enhances Chemotherapy Resistance

Matthew R. M. Jotte, Tanner C. Martinez, Angela Stoddart, Molly K. Imgruet, Henna S. Nam, Bonnie Hu, Saira Khan, Ningfei An, Megan E. McNerney
Journal: Blood
Blood (2023) 142 (Supplement 1): 5689.
https://doi.org/10.1182/blood-2023-189308
Published: 2023
Journal Articles

CUX1 Deficiency Potentiates RAS Signaling to Drive Malignancy

Ningfei An, Molly K Imgruet, Saira Khan, Lia Jueng, Sandeep Gurbuxani, Megan E. McNerney
Journal: Blood
Blood (2021) 138 (Supplement 1): 1159.
https://doi.org/10.1182/blood-2021-148694
Published: 2021
Journal Articles

Loss of a 7q gene, CUX1 , disrupts epigenetically driven DNA repair and drives therapy-related myeloid neoplasms

Molly K. Imgruet, Julian Lutze, Ningfei An, Bonnie Hu, Saira Khan, Jeffrey Kurkewich, Tanner C. Martinez, Donald Wolfgeher, Sandeep K. Gurbuxani, Stephen J. Kron, Megan E. McNerney
Journal: Blood
Blood (2021) 138 (9): 790–805.
https://doi.org/10.1182/blood.2020009195
Published: 2021
Includes: Supplemental data
Journal Articles

Deficiency of CUX1, Encoded on 7q, Blocks the Normal HSC DNA Damage Response and Drives Highly Penetrant Therapy-Related Myeloid Neoplasms in Mice

Molly K Imgruet, BS, Ningfei An, PhD, Saira Khan, MS, Julian K Lutze, BS, Bonnie Hu, Stephen J. Kron, MD PhD, Sandeep Gurbuxani, MBBS, PhD, Megan E. McNerney, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 641.
https://doi.org/10.1182/blood-2019-130717
Published: 2019
Journal Articles

Gene dosage effect of CUX1 in a murine model disrupts HSC homeostasis and controls the severity and mortality of MDS

Ningfei An, Saira Khan, Molly K. Imgruet, Sandeep K. Gurbuxani, Stephanie N. Konecki, Michael R. Burgess, Megan E. McNerney
Journal: Blood
Blood (2018) 131 (24): 2682–2697.
https://doi.org/10.1182/blood-2017-10-810028
Published: 2018
Includes: Supplemental data