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Journal Articles

Single Cell Analysis of Pre-Treatment Peripheral Immune Composition Can Predict CAR-T Outcomes in Patients with Diffuse Large B-Cell Lymphoma

Anna Gurevich Shapiro, Eitan Winter, Pascale Zwicky, Mor Zada, Noam Shapira, Oren Barboy, Paulina Chalan, Reut Sharet-Eshed, Merav Kedmi, Eyal David, Irit Mazza Avivi, Assaf Weiner, Ron Ram, Ido Amit
Journal: Blood
Blood (2024) 144 (Supplement 1): 4788.
https://doi.org/10.1182/blood-2024-203893
Published: 2024
Journal Articles

Determinants of Response to Anti CD-19 CAR-T Cells for Diffuse Large B-Cell Lymphoma in Pre-Treatment Peripheral Blood Mononuclear Cells Using Single-Cell RNA-Seq

Ron Ram, Yonatan Katzenelenbogen, Anna Gurevich Shapiro, Eitan Winter, Oren Barboy, Mor Zada, Shahar Halevi, Eyal David, Irit Avivi Mazza, Ido Amit
Journal: Blood
Blood (2023) 142 (Supplement 1): 4829.
https://doi.org/10.1182/blood-2023-190639
Published: 2023
Journal Articles

Towards a Decision Engine for Therapeutic Optimization of Relapsed Refractory Multiple Myeloma

Yael C. Cohen, Mor Zada, Shuang-Yin Wang, Assaf Weiner, Natan Melamed, Polina Stepensky, Moshe E Gatt, Shlomit Kfir-Erenfeld, Nathalie Asherie, Eyal Lebel, Irit Avivi Mazza, Anna Gurevich Shapiro, Iuliana Vaxman, Tamir Shragai, Paulina Chalan, Eyal David, Ido Amit
Journal: Blood
Blood (2023) 142 (Supplement 1): 341.
https://doi.org/10.1182/blood-2023-190178
Published: 2023
Journal Articles

Unraveling the Mechanism of Action of Bispecific T-Cell Engagers in B-Cell Acute Lymphoblastic Leukemia Using Advanced Single-Cell Multiomics

Anna Gurevich Shapiro, Eitan Winter, Yakir Moshe, Yonatan Katzenelenbogen, Diego Jaitin, Mor Zada, Oren Barboy, Ido Yofe, Paulina Chalan, San Truong Phan, Amir Giladi, Michael Shapiro, Renana Robinson, Eitan Kugler, Ofir Wolach, Irit Avivi Mazza, Ido Amit
Journal: Blood
Blood (2023) 142 (Supplement 1): 599.
https://doi.org/10.1182/blood-2023-188930
Published: 2023
Journal Articles

Daratumumab Carfilzomib Lenalidomide Dexamethasone Provides Effective Salvage for Functionally and Cytogenetically High-Risk Myeloma Patients, Except Those Expressing Module-1 Transcriptional Signature: Extended Follow-up from Kydar Multicenter Clinical/Translational Trial.

Yael C Cohen, Moshe E Gatt, Efrat Luttwak, Noa Lavi, Chezi Ganzel, Evgeni Chubar, Ory Rouvio, Iuliana Vaxman, Oren Pasvolsky, Mouna Ballan, Tamar Tadmor, Anatoly Nemets, Osnat Jarchowsky, Olga Shvetz, Ofer Shpilberg, Najib Dally, Merav Leiba, Assaf Weiner, Mor Zada, Shuang-Yin Wang, Chamutal Gur, Noa Lowenton-Spier, Liron Goor-Porges, Ido Amit, Irit Avivi
Journal: Blood
Blood (2022) 140 (Supplement 1): 4426–4427.
https://doi.org/10.1182/blood-2022-164572
Published: 2022
Journal Articles

Single Cell RNA Sequencing in Patients Enrolled in a Selinexor Clinical Trial Reveals Overexpression of Alternative Nuclear Export Pathways Associated with Resistance to Selinexor in Refractory Multiple Myeloma

Yael C Cohen, Mor Zada, Shuang-Yin Wang, Ohad S. Bentur, Evgeni Chubar, Amos Cohen, Noa Lavi, Hila Magen, Moshe Gatt, Miri Zektser, Merav Leiba, Galia Stemer, Tamir Shragai, Irit Avivi, Assaf Weiner, Ido Amit
Journal: Blood
Blood (2021) 138 (Supplement 1): 2725.
https://doi.org/10.1182/blood-2021-149701
Published: 2021
Journal Articles

A Novel Therapy-Resistance Transcriptional Signature Based on Single Cell Analysis in Kydar Clinical Trial

Yael C Cohen, MD, Mor Zada, MSc, Shuang-Yin Wang, Chamutal Bornstein, PhD, Eyal David, Adi Moshe, PhD, Baoguo Li, PhD, Shir Shlomi, Moshe Gatt, MD, Noa Lavi, MD, Chezi Ganzel, MD, Efrat Lutwak, MD, Ory Rouvio, MD, Iuliana Vaxman, MDBA, Oren Pasvolsky, MD, Mouna Ballan, Tamar Tadmor, MD, Anatoly Nemets, Osnat Jarchowcky Dolberg, Yevgeny Chober, Olga Shvetz, MD, Merav Leiba, Ofer Shpilberg, MD MPH, Nagib Deli, Irit Avivi, MD, Assaf Weiner, PhD, Ido Amit, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 19–20.
https://doi.org/10.1182/blood-2020-139670
Published: 2020
Journal Articles

Kydar Multicenter Trial of Quadruple Regimen for Induction Resistant Myeloma Combined with Translational Single-Cell Analysis Identifies Potential Drivers of Advanced Resistance, Including Novel Immune Checkpoints

Yael C Cohen, MD, Mor Zada, MSc, Moshe E. Gatt, MD, Noa Lavi, MD, Chezi Ganzel, MD, Shuang-Yin Wang, Assaf Weiner, PhD, Guy Ledergor, MD, Evgeni Chubar, MD, Ory Rouvio, MD, Iuliana Vaxman, MDBA, Mouna Ballan, MD, Tamar Tadmor, MD, Anatoly Nemets, MD, Osnat Jarchowcky Dolberg, Olga Shvetz, MD, Ofer Shpilberg, MD MPH, Nagib Deli, MD, Irit Avivi, Ido Amit, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 982.
https://doi.org/10.1182/blood-2019-129618
Published: 2019