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Journal Articles

EP300 Suppresses Leukemia Development in Myelodysplastic Syndrome through Myb Repression

Na Man, Gloria Mas Martin, PhD, Daniel Karl, PhD, Jun Sun, PhD, Fan Liu, PhD, Miguel Torres-Martin, PhD, Hidehiro Itonaga, MD PhD, Concepcion Martinez, B.S., Shi Chen, Stephanie Duffort, Pierre-Jacques Hamard, PhD, Ye Xu, PhD, Luisa Cimmino, PhDBSc, Feng-Chun Yang, MD PhD, Philip A. Cole, MD PhD, Mingjiang Xu, MD PhD, Maria E. Figueroa, MD, Stephen Nimer, MD

Blood (2019) 134 (Supplement_1): 561.

https://doi.org/10.1182/blood-2019-130507

Published: 2019

Journal Articles

TET2 Loss Accelerates Leukemogenesis By Disrupting Mismatch Repair Proteins

Blood (2019) 134 (Supplement_1): 1200.

https://doi.org/10.1182/blood-2019-132005

Published: 2019

Journal Articles

Hottip Lncrna Reinforces CTCF Defined Chromatin Boundaries and Drives Wnt Target Gene Expression in AML Leukemogenesis

Huacheng Luo, Ganqian Zhu, PhD, Tsz Kan Fung, Yi Qiu, PhD, Mingjiang Xu, MD PhD, Chi Wai Eric So, Suming Huang, PhD

Blood (2019) 134 (Supplement_1): 277.

https://doi.org/10.1182/blood-2019-127323

Published: 2019

Journal Articles

Activation of Hottip lncrna Perturbs HSC Function Leading to AML like Disease in Mice

Huacheng Luo, Ganqian Zhu, PhD, Jie Zha, MD, Bowen Yan, Ph. D, Ying Guo, Jianfeng Xu, PhD, Qian Lai, Bing Xu, MD PhD, Feng-Chun Yang, MD PhD, Wei Li, Yi Qiu, Mingjiang Xu, MD PhD, Suming Huang

Blood (2018) 132 (Supplement 1): 3877.

https://doi.org/10.1182/blood-2018-99-110218

Published: 2018

Journal Articles

Suv39h1 Represses the Progression of MLL -Rearranged Myeloid Leukemia Via Hoxb13

Yajing Chu, PhD, Yangpeng Chen, Huidong Guo, PhD, Mengke Li, Jun Shi, MD, Tao Cheng, MD, Feng-Chun Yang, MD PhD, Mingjiang Xu, MD PhD, Weiping Yuan, PhDMD

Blood (2018) 132 (Supplement 1): 3878.

https://doi.org/10.1182/blood-2018-99-113732

Published: 2018

Journal Articles

Cooperative Epigenetic Regulation By ASXL1 and NF1 Loss on Leukemogenesis

Peng Zhang, PhD, Fuhong He, PhD, Jie Bai, MD, Shi Chen, Stephen D. Nimer, MD, Yuan Zhou, PhD, Mingjiang Xu, MD PhD, Qianfei Wang, PhD, Feng-Chun Yang, MD PhD

Blood (2018) 132 (Supplement 1): 652.

https://doi.org/10.1182/blood-2018-99-110964

Published: 2018

Journal Articles

Hoxblinc Is Aberrantly Expressed in Acute Myeloid Leukemia and Functions As a Potent Oncogenic Long Non-Coding RNA in Leukemogenesis

Ganqian Zhu, PhD, Huacheng Luo, Shi Chen, Qian Lai, Ying Guo, Olga A Guryanova, MDPhD, Yi Qiu, Feng-Chun Yang, MD PhD, Wei Li, Stephen D. Nimer, MD, Suming Huang, Mingjiang Xu, MD PhD

Blood (2018) 132 (Supplement 1): 886.

https://doi.org/10.1182/blood-2018-99-112232

Published: 2018

Journal Articles

Modulation of TET2 Activity By Ascorbic Acid and Factors Affecting Lysine Acetylation

Blood (2018) 132 (Supplement 1): 4346.

https://doi.org/10.1182/blood-2018-99-119712

Published: 2018

Journal Articles

ASXL2 Is Required for Normal Hematopoiesis and Loss of a sxl2 Leads to Myeloid Malignancies in Mice

Jianping Li, Fuhong He, PhD, Peng Zhang, PhD, Shi Chen, MD PhD, Hui Shi, Yanling Sun, Guo Ying, Hui Yang, Stephen D. Nimer, MD, Qian-Fei Wang, Mingjiang Xu, MD PhD, Feng-Chun Yang, MD PhD

Blood (2016) 128 (22): 1509.

https://doi.org/10.1182/blood.V128.22.1509.1509

Published: 2016

Journal Articles

Tet2 Loss Dysregulates the Behavior of Mesenchymal Stem Cells and Increases Their Ability to Promote Tet2 -/- -Driven Myeloid Malignancy Progression

Zhigang Zhao, MD PhD, Rong Li, Lin Liu, Jinhuan Wang, Zizhen Chen, Wen Xing, MD, Weiping Yuan, PhDMD, Feng-Chun Yang, MD PhD, Yuan Zhou, PhD, Mingjiang Xu, MD PhD

Blood (2016) 128 (22): 1510.

https://doi.org/10.1182/blood.V128.22.1510.1510

Published: 2016

Journal Articles

Novel Functional Roles for Ten-Eleven-Translocation 2 (Tet2) in Normal and Leukemic Growth of Mast Cells

Raghuveer Mali, PhD, Holly Rene Martin, PhD, Baskar Ramdas, PhD, Lakshmi Palam, PhD, Valeria Visconte, PhD, Tiu Ramon, MD, Helmut Hanenberg, MD, Mingjiang Xu, MD PhD, Reuben Kapur, PhD

Blood (2015) 126 (23): 775.

https://doi.org/10.1182/blood.V126.23.775.775

Published: 2015

Journal Articles

Survival and Prognosis of Chinese Patients with Post-Polycythemia Vera Myelofibrosis

Jie Bai, MD PhD, Yuan Zhou, PhD, Lei Zhang, MD, Mengyao Sheng, Rong Li, Hui Shi, Yanping Xue, MD, Mingjiang Xu, MD PhD, Feng-Chun Yang, MD PhD

Blood (2015) 126 (23): 1607.

https://doi.org/10.1182/blood.V126.23.1607.1607

Published: 2015

Journal Articles

Cooperative Effect of Haploinsufficient ASXL1 and NF1 in Acute Myeloid Leukemia Transformation

Peng Zhang, PhD, Shohei Yamamoto, MD PhD, Shi Chen, MD PhD, Yuan Zhou, PhD, Mingjiang Xu, MD PhD, Feng-Chun Yang, MD PhD

Blood (2015) 126 (23): 1224.

https://doi.org/10.1182/blood.V126.23.1224.1224

Published: 2015

Journal Articles

Cell Autonomous Defects of Mesenchymal Stem Progenitor Cells of Patients with CMML Contribute to Impaired Hematopoietic Supportive Activity

Hui Shi, MD PhD, Rong Li, Wen Xing, MD, Jie Bai, MD PhD, Xiaohui Si, PhD, Mingjiang Xu, MD PhD, Yuan Zhou, PhD, Feng-Chun Yang, MD PhD

Blood (2015) 126 (23): 3599.

https://doi.org/10.1182/blood.V126.23.3599.3599

Published: 2015

Journal Articles

ASXL1 Is a Key Regulator for Erythroid Development and Asxl1 Loss Impairs Erythropoiesis In Vivo

Shohei Yamamoto, MD PhD, Hui Shi, MD PhD, Shi Chen, MD PhD, Peng Zhang, PhD, Yuan Zhou, PhD, Mingjiang Xu, MD PhD, Feng-Chun Yang, MD PhD

Blood (2015) 126 (23): 3644.

https://doi.org/10.1182/blood.V126.23.3644.3644

Published: 2015

Journal Articles

A Phase I Study of LBH589, a Novel Histone Deacetylase Inhibitor in Patients with Primary Myelofibrosis (PMF) and Post-Polycythemia/Essential Thrombocythemia Myelofibrosis (Post-PV/ET MF).

John Mascarenhas, MD, Xiaoli Wang, MD, PhD, Amelyn Rodriguez, BSN, RN, OCN, Mingjiang Xu, MD, PhD, Elaine Gorman, ANP-BC, Wenyong Zhang, MD, PhD, Judith D. Goldberg, Sc.D., Vesna Najfeld, Ph.D., Ronald Hoffman, MD

Blood (2009) 114 (22): 308.

https://doi.org/10.1182/blood.V114.22.308.308

Published: 2009

Journal Articles

Treatment with Pegylated Interferon Alpha 2a in Combination with the Bcl-Xl Inhibitor ABT-737 Specifically Targets JAK2V617F Positive Hematopoietic Progenitor Cells From Patients with Polycythemia Vera.

Min Lu, PhD, Wei Zhang, Daniel Yoo, Dmitriy Berenzon, Yan Li, Xiaoli Wang, MD, PhD, Adam Austin, John Mascarenhas, MD, Mingjiang Xu, MD, PhD, Ronald Hoffman, MD

Blood (2009) 114 (22): 3916.

https://doi.org/10.1182/blood.V114.22.3916.3916

Published: 2009

Journal Articles

Treatment in Vitro with a Combination of Bcl-Xl Inhibitor-ABT-737 and a JAK2 Inhibitor Selectively Eliminates JAK2V617F MPN Progenitor Cells.

Min Lu, PhD, Wei Zhang, Jiapeng Wang, Yan Li, Xiaoli Wang, MD, PhD, Daniel Yoo, Adam Austin, John Mascarenhas, MD, Zhizhuang Joe Zhao, Ronald Hoffman, MD, Mingjiang Xu, MD, PhD

Blood (2009) 114 (22): 752.

https://doi.org/10.1182/blood.V114.22.752.752

Published: 2009

Journal Articles

Sequential Treatment of CD34 + Cells From Patients with Primary Myelofibrosis with Chromatin Modifying Agents Alters the Behavior of JAK2V617F Positive NOD/SCID Marrow Repopulating Cells.

Xiaoli Wang, MD, PhD, Wei Zhang, Adam Austin, Daniel Yoo, Min Lu, Mingjiang Xu, MD, PhD, Ronald Hoffman, MD

Blood (2009) 114 (22): 1910.

https://doi.org/10.1182/blood.V114.22.1910.1910

Published: 2009

Journal Articles

Identification of the Origins and Characterization of the Consequences of Megakaryocytic Hyperplasia in Idiopathic Myelofibrosis.

Stefan O. Ciurea, MD, Nadim Mahmud, MD, PhD, Edward Bruno, MS, Takefumi Ishii, MD, Mingjiang Xu, MD. PhD, Ronald Hoffman, MD

Blood (2006) 108 (11): 663.

https://doi.org/10.1182/blood.V108.11.663.663

Published: 2006

NARROW

EP300 Suppresses Leukemia Development in Myelodysplastic Syndrome through Myb Repression

TET2 Loss Accelerates Leukemogenesis By Disrupting Mismatch Repair Proteins

Hottip Lncrna Reinforces CTCF Defined Chromatin Boundaries and Drives Wnt Target Gene Expression in AML Leukemogenesis

Activation of Hottip lncrna Perturbs HSC Function Leading to AML like Disease in Mice

Suv39h1 Represses the Progression of MLL -Rearranged Myeloid Leukemia Via Hoxb13

Cooperative Epigenetic Regulation By ASXL1 and NF1 Loss on Leukemogenesis

Hoxblinc Is Aberrantly Expressed in Acute Myeloid Leukemia and Functions As a Potent Oncogenic Long Non-Coding RNA in Leukemogenesis

Modulation of TET2 Activity By Ascorbic Acid and Factors Affecting Lysine Acetylation

ASXL2 Is Required for Normal Hematopoiesis and Loss of a sxl2 Leads to Myeloid Malignancies in Mice

Tet2 Loss Dysregulates the Behavior of Mesenchymal Stem Cells and Increases Their Ability to Promote Tet2 -/- -Driven Myeloid Malignancy Progression

Novel Functional Roles for Ten-Eleven-Translocation 2 (Tet2) in Normal and Leukemic Growth of Mast Cells

Survival and Prognosis of Chinese Patients with Post-Polycythemia Vera Myelofibrosis

Cooperative Effect of Haploinsufficient ASXL1 and NF1 in Acute Myeloid Leukemia Transformation

Cell Autonomous Defects of Mesenchymal Stem Progenitor Cells of Patients with CMML Contribute to Impaired Hematopoietic Supportive Activity

ASXL1 Is a Key Regulator for Erythroid Development and Asxl1 Loss Impairs Erythropoiesis In Vivo

A Phase I Study of LBH589, a Novel Histone Deacetylase Inhibitor in Patients with Primary Myelofibrosis (PMF) and Post-Polycythemia/Essential Thrombocythemia Myelofibrosis (Post-PV/ET MF).

Treatment with Pegylated Interferon Alpha 2a in Combination with the Bcl-Xl Inhibitor ABT-737 Specifically Targets JAK2V617F Positive Hematopoietic Progenitor Cells From Patients with Polycythemia Vera.

Treatment in Vitro with a Combination of Bcl-Xl Inhibitor-ABT-737 and a JAK2 Inhibitor Selectively Eliminates JAK2V617F MPN Progenitor Cells.

Sequential Treatment of CD34 + Cells From Patients with Primary Myelofibrosis with Chromatin Modifying Agents Alters the Behavior of JAK2V617F Positive NOD/SCID Marrow Repopulating Cells.

Identification of the Origins and Characterization of the Consequences of Megakaryocytic Hyperplasia in Idiopathic Myelofibrosis.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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