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Journal Articles

Immunocluster: A Computational Tool to Explore the Immune Profile and Cellular Heterogeneity of Hematological Diseases Using Liquid and Imaging Mass, and Flow Cytometry Data

Jessica A. Timms, James W Opzoomer, Kevin Blighe, PhD, Benedetta Apollonio, PhD, Thanos Mourikis, Nicolas Chapuis, PharmD, PhD, Richard Bekoe, Alan G. Ramsay, BSc,MSc,PhD, Donal P. McLornan, MRCP, PhD FRCPath, Claire Harrison, DM, FRCP, FRCPath, Paul R. Barber, Peter Parker, Michaela Fontenay, MD PhD, James N. Arnold, Shahram Kordasti, MD PhD

Blood (2020) 136 (Supplement 1): 9–10.

https://doi.org/10.1182/blood-2020-140258

Published: 2020

Journal Articles

TP53 State Dictates Genome Stability, Clinical Presentation and Outcomes in Myelodysplastic Syndromes

Elsa Bernard, PhD, Yasuhito Nannya, MD PhD, Tetsuichi Yoshizato, MD PhD, Robert P. Hasserjian, MD, Ryunosuke Saiki, Yusuke Shiozawa, MD PhD, Sean M. Devlin, PhD, Heinz Tuechler, Araxe Sarian, Luca Malcovati, MD, Francesc Sole, PhD, Detlef Haase, MD, Maria Creignou, Max Levine, MS, Ulrich Germing, MD, Catherine Cargo, MB, FRCPath, Yanming Zhang, MD, Juan Medina, MS, Juan E. Arango Ossa, BS, Julie Schanz, MD PhD, Arjan van de Loosdrecht, MD PhD, Martin Jädersten, MD PhD, John M. Bennett, MD, Magnus Tobiasson, MD PhD, Olivier Kosmider, PharmD, PhD, Matilde Y Follo, PhD, Felicitas Thol, MD, Ronald F Pinheiro, MD, Valeria Santini, MD, Ioannis Kotsianidis, Jacqueline Boultwood, Fabio PS Santos, MD, Senji Kasahara, MD PhD, Takayuki Ishikawa, MD PhD, Hisashi Tsurumi, MD PhD, Akifumi Takaori-Kondo, MD PhD, Toru Kiguchi, Chantana Polprasert, MD, Virginia M. Klimek, MD, Michael R. Savona, MD, Monika Belickova, PhD, Christina Ganster, Lionel Ades, MD PhD, Matteo Giovanni Della Porta, MD, Alexandra Smith, PhD, Yesenia Werner, Minal A Patel, MPH, Agnes Viale, PhD, Katelynd Vanness, Donna S Neuberg, ScD, Kristen E. Stevenson, MS, Kamal Menghrajani, MD, Kelly Bolton, MD PhD, Pierre Fenaux, MD PhD, Andrea Pellagatti, Uwe Platzbecker, MD, Michael Heuser, MD, Peter Valent, MD, Shigeru Chiba, MD PhD, Yasushi Miyazaki, MD PhD, Carlo Finelli, Maria Teresa Voso, MD, Lee-Yung Shih, MD, Michaela Fontenay, MD PhD, Joop H. Jansen, PhD, José Cervera, MD PhD, Yoshiko Atsuta, MD PhD, Norbert Gattermann, MD, Benjamin L. Ebert, MD PhD, Rafael Bejar, MD PhD, Peter L Greenberg, MD, Mario Cazzola, MD, Eva Hellstrom Lindberg, MD PhD, Seishi Ogawa, MD PhD, Elli Papaemmanuil, PhD

Blood (2019) 134 (Supplement_1): 675.

https://doi.org/10.1182/blood-2019-129392

Published: 2019

Journal Articles

Effect of Rap-536 on MDS PDX-Murine Models with or without SF3B1 Mutation

Mathieu Meunier, Camille Knosp, Chloe Friedrich, Johanna Zannoni, Jean-Yves Cahn, MD PhD, Olivier Kosmider, PharmD, PhD, Michaela Fontenay, MD PhD, Sophie Park, MD PhD

Blood (2019) 134 (Supplement_1): 1705.

https://doi.org/10.1182/blood-2019-128407

Published: 2019

Journal Articles

Bone Marrow Niche-Derived Extracellular Matrix-Degrading Enzymes Influence the Progression of B-Cell Acute Lymphoblastic Leukemia

Divij Verma, MSc, Costanza Zanetti, MSc, Michaela Fontenay, MD PhD, Daniela S. Krause, MD

Blood (2018) 132 (Supplement 1): 390.

https://doi.org/10.1182/blood-2018-99-110492

Published: 2018

Journal Articles

Ribosome Biogenesis Controls Erythroid Differentiation Via a p53-Dependent Transcriptional Checkpoint and Its Limitation By RPS14 Haploinsufficiency Results in Selective Defects in Translation

Ismael Boussaid, PharmD, Salome Le Goff, PhDstudent, Celia Floquet, Post-doc, Anna Raimbault, PharmD, PhD, Charlotte Andrieu-Soler, Emilie-fleur Gautier, PhD, Olivier Kosmider, Isabelle Hatin, PhD, Mohandas Narla, DSc, Eric Soler, PhD, Patrick Mayeux, PhD, Michaela Fontenay, MD PhD

Blood (2017) 130 (Supplement 1): 83.

https://doi.org/10.1182/blood.V130.Suppl_1.83.83

Published: 2017

Journal Articles

Warfarin Impairs the Bone Marrow Microenvironment and Hematopoiesis Via the Periostin/Integrin Î²3 Pathway

Divij Verma, MSc, Keertik Fulzele, Kumar Rahul, Christina Karantanou, Raquel Pereira, Kathrin Kunz, Soraya Hoelper, Eva Weissenberger, Paul K. Ziegler, Sara Zia- Chahabi, Michaela Fontenay, MD PhD, Paola Divieti Pajevic, Daniela S. Krause, MD

Blood (2017) 130 (Supplement 1): 2444.

https://doi.org/10.1182/blood.V130.Suppl_1.2444.2444

Published: 2017

Journal Articles

Lenalidomide-Mediated Erythroid Improvement in Non-Del(5q) Myelodysplastic Syndromes Is Associated with Bone Marrow Immuno-Remodeling

Gwenneg Kerdivel, PhD, Virginie Chesnais, PhD, Etienne Becht, PhD, Andrea Toma, MD PhD, Nicolas Cagnard, PhD, Florent Dumont, PhD, Alice Rousseau, Pierre Fenaux, MD PhD, Sylvie Chevret, MD PhD, Nicolas Chapuis, PharmD, PhD, Valentina Boeva, PhD, Wolf-Herman Fridman, Olivier Kosmider, Michaela Fontenay, MD PhD

Blood (2017) 130 (Supplement 1): 2983.

https://doi.org/10.1182/blood.V130.Suppl_1.2983.2983

Published: 2017

Journal Articles

Oxidative Stress in Stem / Progenitor Cells and Specific Antioxidant Response in Bone Marrow from Myelodysplastic Syndrome Patients

Frederic Picou, PhD, Christine Vignon, PhD, Joelle Hanna, MD, Sebastien Lachot, MD, Marie-Helene Estienne, PharmD, Amelie Foucault, Frederic Mazurier, PhD, Florence Rouleux-Bonnin, PhD, Fabrice Gouilleux, PhD, Jorge Domenech, MDPhD, Emmanuel Gyan, MDPhD, Michaela Fontenay, MD PhD, Olivier Herault, MDPhD

Blood (2017) 130 (Supplement 1): 2951.

https://doi.org/10.1182/blood.V130.Suppl_1.2951.2951

Published: 2017

Journal Articles

Dyserythropoiesis Evaluated By Red Score and Hepcidin/Ferritin Levels Predicts Response to Epoetin Zeta in Lower Risk MDS

Blood (2017) 130 (Supplement 1): 1705.

https://doi.org/10.1182/blood.V130.Suppl_1.1705.1705

Published: 2017

Journal Articles

Prognostic Role of Gene Mutations in Chronic Myelomonocytic Leukemia (CMML) Patients Treated with Hypomethylating Agents. a Report on 183 Patients

Blood (2017) 130 (Supplement 1): 159.

https://doi.org/10.1182/blood.V130.Suppl_1.159.159

Published: 2017

Journal Articles

Architectural and Functional Heterogeneity of Hematopoietic Stem/Progenitor Cells in Non-Del(5q) Myelodysplastic Syndromes

Virginie Chesnais, Marie-laure Arcangeli, PhD, Caroline Delette, Alice Rousseau, M'boyba Khadija Diop, Andrea Lefevre, Meyling H. Cheok, MSPharm, PhD, Nicolas Chapuis, PharmD, PhD, Laurence Legros, MD PhD, Sophie Raynaud, MD, Lise Willems, MD PhD, Didier Bouscary, MD PhD, Evelyne Lauret, PhD, Olivier A. Bernard, PhD, Olivier Kosmider, MD PhD, Francoise Pflumio, PhD, Michaela Fontenay, MD PhD

Blood (2016) 128 (22): 3153.

https://doi.org/10.1182/blood.V128.22.3153.3153

Published: 2016

Journal Articles

Comparison of the Molecular Spectrum of Lenalidomide-Treated Myelodysplastic Syndrome with and without Del(5q)

Blood (2016) 128 (22): 3172.

https://doi.org/10.1182/blood.V128.22.3172.3172

Published: 2016

Journal Articles

Gene Expression and Alternative Splicing Datasets Analyses of MDS with Ring Sideroblasts Highlight Alternative Branchpoint Usage in Genes Involved in Iron Metabolism and Erythropoiesis

Abderrahmane Bousta, Sabrina Bondu, Alexandre Houy, Nicolas Cagnard, Carine Lefevre, Delphine Bernard, PhD, Marc-Henri Stern, MD PhD, Michaela Fontenay, MD PhD, Olivier Kosmider, MD PhD

Blood (2016) 128 (22): 1972.

https://doi.org/10.1182/blood.V128.22.1972.1972

Published: 2016

Journal Articles

Proof of Principle for Mutations Monitoring Using Picoliter-Droplet Digital PCR on DNA and Living Cells: Application to Myelodysplastic Syndromes

Hélène Guermouche, Philippe Nizard, PhD, Heng Lu, PhD, Charles Decraene, Juliette Nectoux, PhD, Pierre Laurent-Puig, PhD, Charlotte Proudhon, PhD, Michaela Fontenay, MD PhD, Valérie Taly, PhD, Olivier Kosmider, MD PhD

Blood (2016) 128 (22): 5515.

https://doi.org/10.1182/blood.V128.22.5515.5515

Published: 2016

Journal Articles

Somatic Mutations in MDS Patients Are Associated with Clinical Features and Predict Prognosis Independent of the IPSS-R: Analysis of Combined Datasets from the International Working Group for Prognosis in MDS-Molecular Committee

Blood (2015) 126 (23): 907.

https://doi.org/10.1182/blood.V126.23.907.907

Published: 2015

Journal Articles

A Two-Gene Classifier for Chronic Myelomonocytic Leukemia (CMML) Patients Treated with Hypomethylating Agents (HMA): A Report By the GFM

Blood (2015) 126 (23): 2872.

https://doi.org/10.1182/blood.V126.23.2872.2872

Published: 2015

Journal Articles

Collapse of Ribosome Biogenesis Induces Rapid Erythroblast Differentiation

Anna Raimbault, Celia Floquet, PhD, Boris Guyot, Ulku Cuhadar, Olivier Kosmider, MD PhD, Francois Morle, PhD, Patrick Mayeux, PhD, Michaela Fontenay, MD PhD

Blood (2014) 124 (21): 2671.

https://doi.org/10.1182/blood.V124.21.2671.2671

Published: 2014

Journal Articles

Prognostic Factors of Response to Erythropoiesis Stimulating Agents (ESA) Treatment in Non RBC Transfusion Dependent Lower Risk MDS. Preliminary Results of a French and Italian Study (on behalf of the GFM and FISM).

Blood (2012) 120 (21): 2814.

https://doi.org/10.1182/blood.V120.21.2814.2814

Published: 2012

Journal Articles

Two Distinct Mechanisms Contribute to Granulomonocytic Hyperplasia in Chronic Myelomonocytic Leukemias (CMML)

Raphael Itzykson, Olivier Kosmider, MD, PhD, Aline Renneville, Margot Morabito, Dorothee Buet, Claude Preudhomme, Céline Berthon, MD, PhD, Lionel Ades, MD, PhD, Pierre Fenaux, MD, PhD, Uwe Platzbecker, MD, Olivier Gagey, Philippe Rameau, Francois Delhommeau, PharmD, PHD, Olivier A. Bernard, PhD, Michaela Fontenay, MD, PhD, William Vainchenker, MD, PhD, Nathalie Droin, Ph.D, Eric Solary

Blood (2012) 120 (21): 309.

https://doi.org/10.1182/blood.V120.21.309.309

Published: 2012

Journal Articles

BCOR Mutations Represent an Independent Factor of Poor Prognosis in Myelodysplastic Syndromes

Blood (2012) 120 (21): 1697.

https://doi.org/10.1182/blood.V120.21.1697.1697

Published: 2012

NARROW

Immunocluster: A Computational Tool to Explore the Immune Profile and Cellular Heterogeneity of Hematological Diseases Using Liquid and Imaging Mass, and Flow Cytometry Data

TP53 State Dictates Genome Stability, Clinical Presentation and Outcomes in Myelodysplastic Syndromes

Effect of Rap-536 on MDS PDX-Murine Models with or without SF3B1 Mutation

Bone Marrow Niche-Derived Extracellular Matrix-Degrading Enzymes Influence the Progression of B-Cell Acute Lymphoblastic Leukemia

Ribosome Biogenesis Controls Erythroid Differentiation Via a p53-Dependent Transcriptional Checkpoint and Its Limitation By RPS14 Haploinsufficiency Results in Selective Defects in Translation

Warfarin Impairs the Bone Marrow Microenvironment and Hematopoiesis Via the Periostin/Integrin Î²3 Pathway

Lenalidomide-Mediated Erythroid Improvement in Non-Del(5q) Myelodysplastic Syndromes Is Associated with Bone Marrow Immuno-Remodeling

Oxidative Stress in Stem / Progenitor Cells and Specific Antioxidant Response in Bone Marrow from Myelodysplastic Syndrome Patients

Dyserythropoiesis Evaluated By Red Score and Hepcidin/Ferritin Levels Predicts Response to Epoetin Zeta in Lower Risk MDS

Prognostic Role of Gene Mutations in Chronic Myelomonocytic Leukemia (CMML) Patients Treated with Hypomethylating Agents. a Report on 183 Patients

Architectural and Functional Heterogeneity of Hematopoietic Stem/Progenitor Cells in Non-Del(5q) Myelodysplastic Syndromes

Comparison of the Molecular Spectrum of Lenalidomide-Treated Myelodysplastic Syndrome with and without Del(5q)

Gene Expression and Alternative Splicing Datasets Analyses of MDS with Ring Sideroblasts Highlight Alternative Branchpoint Usage in Genes Involved in Iron Metabolism and Erythropoiesis

Proof of Principle for Mutations Monitoring Using Picoliter-Droplet Digital PCR on DNA and Living Cells: Application to Myelodysplastic Syndromes

Somatic Mutations in MDS Patients Are Associated with Clinical Features and Predict Prognosis Independent of the IPSS-R: Analysis of Combined Datasets from the International Working Group for Prognosis in MDS-Molecular Committee

A Two-Gene Classifier for Chronic Myelomonocytic Leukemia (CMML) Patients Treated with Hypomethylating Agents (HMA): A Report By the GFM

Collapse of Ribosome Biogenesis Induces Rapid Erythroblast Differentiation

Prognostic Factors of Response to Erythropoiesis Stimulating Agents (ESA) Treatment in Non RBC Transfusion Dependent Lower Risk MDS. Preliminary Results of a French and Italian Study (on behalf of the GFM and FISM).

Two Distinct Mechanisms Contribute to Granulomonocytic Hyperplasia in Chronic Myelomonocytic Leukemias (CMML)

BCOR Mutations Represent an Independent Factor of Poor Prognosis in Myelodysplastic Syndromes

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