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Journal Articles

No Evidence for Hematopoietic Stem Cell Self-Renewal in-Vivo Following Inflammatory Challenge

Blood (2019) 134 (Supplement_1): 456.

https://doi.org/10.1182/blood-2019-125744

Published: 2019

Journal Articles

Deconvolution of Hematopoietic Commitment Decisions By Genome-Wide Analysis of Progressive DNA Methylation Changes

Blood (2019) 134 (Supplement_1): 1179.

https://doi.org/10.1182/blood-2019-124429

Published: 2019

Journal Articles

A Stem Cell-Based Epigenetic Memory Mediates Interferon Response-Heterogeneity within the Hematopoietic System

Simon Haas, PhD, Christoph Hirche, PhD, Alexandra Schnell, Can Sönmezer, Jens Langstein, Stephan Wurzer, PhD, Marc Thier, PhD, Sandra Blaszkiewicz, Franziska Pilz, Michael D. Milsom, PhD, Andreas Trumpp, Prof, PhD, Daniel Lipka, MD, Ulrich Kalinke, Prof, PhD, Marieke A. G. Essers, PhD

Blood (2017) 130 (Supplement 1): 634.

https://doi.org/10.1182/blood.V130.Suppl_1.634.634

Published: 2017

Journal Articles

The RET Receptor Tyrosine Kinase Promotes Acute Myeloid Leukemia through Protection of FLT3-ITD Mutants from Autophagic Degradation

Saskia Rudat, MSc, Anja Pfaus, MSc, Claudia Bühler, MD, Sophie Rabe, MSc, Lars Bullinger, MD, Stefan Gröschel, MD, Stephen M. Sykes, PhD, Michael D. Milsom, PhD, Jana M. Ellegast, MD, Stefan Fröhling, MD, Claudia Scholl, MD

Blood (2016) 128 (22): 2849.

https://doi.org/10.1182/blood.V128.22.2849.2849

Published: 2016

Journal Articles

Hematopoietic Stem Cells Fail to Regenerate In Vivo Following Inflammatory Stress

Blood (2016) 128 (22): 1472.

https://doi.org/10.1182/blood.V128.22.1472.1472

Published: 2016

Journal Articles

Stem Cell-like Megakaryocyte Progenitors As Driving Forces of IFN-Induced Emergency Megakaryopooesis

Blood (2015) 126 (23): 2391.

https://doi.org/10.1182/blood.V126.23.2391.2391

Published: 2015

Journal Articles

Pkc Epsilon Regulates Mitochondrial Redox Biology to Support the Differentiation Blockade in Acute Myeloid Leukemia

Daniela Di Marcantonio, PhD, Jessica Vadaketh, Esteban Martinez, Prisco Mirandola, PhD, Giuliana Gobbi, PhD, Michael D. Milsom, PhD, Claudia Scholl, Stefan Fröhling, Marco Vitale, MD, Stephen Matthew Sykes, PhD

Blood (2015) 126 (23): 444.

https://doi.org/10.1182/blood.V126.23.444.444

Published: 2015

Journal Articles

Stem Cell Replicative Stress and Clonal Exhaustion

Michael D. Milsom, PhD

Blood (2015) 126 (23): SCI-41.

https://doi.org/10.1182/blood.V126.23.SCI-41.SCI-41

Published: 2015

Journal Articles

Altered HSC Metabolism in Response to Stress Leads to De Novo dna Damage and Cellular Attrition

Blood (2014) 124 (21): 255.

https://doi.org/10.1182/blood.V124.21.255.255

Published: 2014

Journal Articles

Optimization of Bcl11a Knockdown By miRNA Scaffold Embedded Shrnas Leading to Enhanced Induction of Fetal Hemoglobin in Erythroid Cells for the Treatment of Beta-Hemoglobinopathies

Christian Brendel, PhD, Swaroopa Guda, PhD, Raffaele Renella, MD PhD, Peng Du, PhD, Daniel E. Bauer, MD, PhD, Matthew C. Canver, BS, Sophia C. Kamran, MD, James Thornton, PhD, Helen de Boer, BAS, Michael D. Milsom, PhD, Stuart H. Orkin, MD, Richard Gregory, PhD, David A. Williams, MD

Blood (2014) 124 (21): 2150.

https://doi.org/10.1182/blood.V124.21.2150.2150

Published: 2014

Journal Articles

Requirement For CDK6 In MLL-Rearranged Acute Myeloid Leukemia

Theresa Placke, PhD, Katrin Faber, PhD, Atsushi Nonami, MD, Helmut R. Salih, MD, Stephen M. Sykes, PhD, David E. Root, PhD, David A. Barbie, MD, William C. Hahn, MD, PhD, Michael D. Milsom, PhD, Claudia Scholl, MD, Stefan Fröhling, MD

Blood (2013) 122 (21): 3782.

https://doi.org/10.1182/blood.V122.21.3782.3782

Published: 2013

Journal Articles

HSC Exit From Dormancy Provokes De Novo DNA Damage, Leading To Bone Marrow Failure If Unresolved By The Fanconi Anemia Pathway

Dagmar Walter, PhD, Amelie Lier, Anja Geiselhart, Sina Huntscha, David Brocks, Irem Bayindir, Paul Kaschutnig, Peter Schmezer, PhD, Steven W Lane, MD, PhD, Marieke Essers, PhD, David A. Williams, MD, Andreas Trumpp, PhD, Michael D. Milsom, PhD

Blood (2013) 122 (21): 799.

https://doi.org/10.1182/blood.V122.21.799.799

Published: 2013

Journal Articles

Hematopoietic SIN Lentiviral Micro RNA-Mediated Silencing of BCL11A: Pre-Clinical Evidence for a Sickle Cell Disease Gene-Therapy Trial

Raffaele Renella, MD, PhD, Aleksej Perlov, Chad E Harris, Daniel E. Bauer, MD, PhD, Jian Xu, PhD, Swaroopa Guda, PhD, Michael D. Milsom, PhD, Stuart H. Orkin, MD, David A. Williams, MD

Blood (2012) 120 (21): 753.

https://doi.org/10.1182/blood.V120.21.753.753

Published: 2012

Journal Articles

Pak A Proteins Are Essential for Hematopoietic Stem/Progenitor Cell (HSC/P) Engraftment Through Regulation of Signaling Pathways Controlling HSC/P Proliferation, Survival, Migration, and the Actin Cytoskeleton

Adrienne M. Dorrance, PhD, Rachelle Kosoff, Meaghan McGuinness, Chad Harris, Serena De Vita, MD, PhD, Ronald Mathieu, Steven W. Lane, MD, Michael D. Milsom, PhD, Jonathan Chernoff, MD, PhD, David A. Williams, MD

Blood (2011) 118 (21): 917.

https://doi.org/10.1182/blood.V118.21.917.917

Published: 2011

Journal Articles

Gene-Correction Rescues Reprogramming of Fanconi Anemia Fibroblasts and Enables Hematopoietic Differentiation of FA Induced Pluripotent Stem Cells in Vitro and In Vivo

Lars Mueller, MD, Michael D. Milsom, PhD, Chad Harris, Rutesh Vyas, Kristina Brumme, Kalindi Parmar, PhD, Axel Schambach, MD PhD, Elke Grassman, Ph.D., In-Hyun Park, PhD, London Wendy, PhD, Kelly Strait, Thorsten Schlaeger, Ph.D, Alexander L. Devine, Alan D. D'Andrea, MD, George Q. Daley, MD, PhD, David A. Williams, MD

Blood (2011) 118 (21): 672.

https://doi.org/10.1182/blood.V118.21.672.672

Published: 2011

Journal Articles

Mechanisms of Resistance to Reprogramming of Cells Defective In the Fanconi Anemia DNA Repair Pathway

Lars Mueller, MD, Michael D. Milsom, PhD, Kristina Brumme, Chad Harris, Kalindi Parmar, PhD, Kaya Zhu, London Wendy, PhD, Kelly Strait, Alan D. D'Andrea, MD, George Q. Daley, MD, PhD, David A. Williams, MD

Blood (2010) 116 (21): 196.

https://doi.org/10.1182/blood.V116.21.196.196

Published: 2010

Journal Articles

Intact Rac Signaling Is Important for Leukemia Cell Survival

Anja Troeger, MD, Pascal-David Johann, Mumine Senturk, Michael D. Milsom, PhD, David A. Williams, MD

Blood (2010) 116 (21): 2885.

https://doi.org/10.1182/blood.V116.21.2885.2885

Published: 2010

Journal Articles

Group A Pak Proteins Are Essential for HSC/P Engraftment.

Adrienne M. Dorrance, PhD, Abel Sanchez-Aguilera, PhD, Serena De Vita, MD, PhD, Michael D. Milsom, PhD, Jonathan Chernoff, MD, PhD, David A. Williams, MD

Blood (2010) 116 (21): 2624.

https://doi.org/10.1182/blood.V116.21.2624.2624

Published: 2010

Journal Articles

The Rho GTPase Rac1 Is Not Required for Definitive Hematopoietic Specification in ES-Derived Hematopoiesis.

Michael D. Milsom, PhD, Akiko Yabuuchi, PhD, George Q. Daley, MD, PhD, David A. Williams, MD

Blood (2009) 114 (22): 1494.

https://doi.org/10.1182/blood.V114.22.1494.1494

Published: 2009

Journal Articles

Ectopic HOXB4 Overcomes the Inhibitory Effect of TNFα on Hematopoietic Stem and Progenitor Cells in a Murine Fanconi Anemia Model.

Michael D. Milsom, PhD, Bernhard Schiedlmeier, PhD, Jeff Bailey, Abdullah Ali, MiOk Kim, PhD, Christopher Baum, MD, Michael Jansen, PhD, David A. Williams, MD

Blood (2008) 112 (11): 2041.

https://doi.org/10.1182/blood.V112.11.2041.2041

Published: 2008

NARROW

No Evidence for Hematopoietic Stem Cell Self-Renewal in-Vivo Following Inflammatory Challenge

Deconvolution of Hematopoietic Commitment Decisions By Genome-Wide Analysis of Progressive DNA Methylation Changes

A Stem Cell-Based Epigenetic Memory Mediates Interferon Response-Heterogeneity within the Hematopoietic System

The RET Receptor Tyrosine Kinase Promotes Acute Myeloid Leukemia through Protection of FLT3-ITD Mutants from Autophagic Degradation

Hematopoietic Stem Cells Fail to Regenerate In Vivo Following Inflammatory Stress

Stem Cell-like Megakaryocyte Progenitors As Driving Forces of IFN-Induced Emergency Megakaryopooesis

Pkc Epsilon Regulates Mitochondrial Redox Biology to Support the Differentiation Blockade in Acute Myeloid Leukemia

Stem Cell Replicative Stress and Clonal Exhaustion

Altered HSC Metabolism in Response to Stress Leads to De Novo dna Damage and Cellular Attrition

Optimization of Bcl11a Knockdown By miRNA Scaffold Embedded Shrnas Leading to Enhanced Induction of Fetal Hemoglobin in Erythroid Cells for the Treatment of Beta-Hemoglobinopathies

Requirement For CDK6 In MLL-Rearranged Acute Myeloid Leukemia

HSC Exit From Dormancy Provokes De Novo DNA Damage, Leading To Bone Marrow Failure If Unresolved By The Fanconi Anemia Pathway

Hematopoietic SIN Lentiviral Micro RNA-Mediated Silencing of BCL11A: Pre-Clinical Evidence for a Sickle Cell Disease Gene-Therapy Trial

Pak A Proteins Are Essential for Hematopoietic Stem/Progenitor Cell (HSC/P) Engraftment Through Regulation of Signaling Pathways Controlling HSC/P Proliferation, Survival, Migration, and the Actin Cytoskeleton

Gene-Correction Rescues Reprogramming of Fanconi Anemia Fibroblasts and Enables Hematopoietic Differentiation of FA Induced Pluripotent Stem Cells in Vitro and In Vivo

Mechanisms of Resistance to Reprogramming of Cells Defective In the Fanconi Anemia DNA Repair Pathway

Intact Rac Signaling Is Important for Leukemia Cell Survival

Group A Pak Proteins Are Essential for HSC/P Engraftment.

The Rho GTPase Rac1 Is Not Required for Definitive Hematopoietic Specification in ES-Derived Hematopoiesis.

Ectopic HOXB4 Overcomes the Inhibitory Effect of TNFα on Hematopoietic Stem and Progenitor Cells in a Murine Fanconi Anemia Model.

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American Society of Hematology

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American Society of Hematology

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