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Mechthild Jonas
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Journal Articles

SGN-CD123A, a Pyrrolobenzodiazepine Dimer Linked Anti-CD123 Antibody Drug Conjugate, Demonstrates Effective Anti-Leukemic Activity in Multiple Preclinical Models of AML

May S.K. Sutherland, PhD, Changpu Yu, Roland B. Walter, MD PhD, Lori Westendorf, John Valliere-Douglass, PhD, Lucy Pan, PhD, Django Sussman, PhD, Martha Anderson, Weiping Zeng, Ivan Stone, Kerry Klussman, Michelle Ulrich, Mechthild Jonas, PhD, Peter Senter, PhD, Jonathan G. Drachman, MD, Dennis Benjamin, PhD
Journal: Blood
Blood (2015) 126 (23): 330.
https://doi.org/10.1182/blood.V126.23.330.330
Published: 2015
Journal Articles

The Humanized Anti-CD40 Monoclonal Antibody, SGN-40, Potentiates Chemotherapy Regimens in NHL Xenograft Models Via Pro-Apoptotic Signaling.

Timothy S. Lewis, PhD, Renee S. McCormick, B.S., Kim Kissler, B.S., Ivan J. Stone, B.S., Mechthild Jonas, Ph.D., May S.K. Sutherland, Ph.D., Hans-Peter Gerber, Ph.D., Jonathan G. Drachman, M.D., Iqbal S. Grewal, Ph.D., Che-Leung Law, Ph.D.
Journal: Blood
Blood (2007) 110 (11): 2342.
https://doi.org/10.1182/blood.V110.11.2342.2342
Published: 2007
Journal Articles

The Humanized Anti-CD40 Antibody, SGN-40, Promotes Apoptosis Signaling and Is Effective in Combination with Standard Therapies in Lymphoma Xenograft Models.

Timothy S. Lewis, PhD, May S.K. Sutherland, Ph.D., Mechthild Jonas, Ph.D., Charles G. Cerveny, M.S., Renee McCormick, B.S., Alan F. Wahl, Ph.D., Jonathan G. Drachman, M.D., Iqbal S. Grewal, Ph.D., Che-Leung Law, Ph.D.
Journal: Blood
Blood (2006) 108 (11): 2499.
https://doi.org/10.1182/blood.V108.11.2499.2499
Published: 2006
Journal Articles

Broad-spectrum caspase inhibition paradoxically augments cell death in TNF-α–stimulated neutrophils

Chien-Ying Liu, Akihiro Takemasa, W. Conrad Liles, Richard B. Goodman, Mechthild Jonas, Henry Rosen, Emil Chi, Robert K. Winn, John M. Harlan, Peter I. Chuang
Journal: Blood
Blood (2003) 101 (1): 295–304.
https://doi.org/10.1182/blood-2001-12-0266
Published: 2003
Journal Articles

Impaired survival of bone marrow hematopoietic progenitor cells in cyclic neutropenia

Andrew A. G. Aprikyan, W. Conrad Liles, Elin Rodger, Mechthild Jonas, Emil Y. Chi, David C. Dale
Journal: Blood
Blood (2001) 97 (1): 147–153.
https://doi.org/10.1182/blood.V97.1.147
Published: 2001
Journal Articles

Myelokathexis, a congenital disorder of severe neutropenia characterized by accelerated apoptosis and defective expression of bcl-x in neutrophil precursors

Andrew A. G. Aprikyan, W. Conrad Liles, Julie R. Park, Mechthild Jonas, Emil Y. Chi, David C. Dale
Journal: Blood
Blood (2000) 95 (1): 320–327.
https://doi.org/10.1182/blood.V95.1.320
Published: 2000