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Journal Articles

Chronic Lymphocytic Leukemia Patients with IGHV Genes Carrying Only Silent Mutations Have A Longer Time From Diagnosis to Initial Therapy Than Patients Expressing B-Cell Receptors with No Somatic Mutations

Matthew Kaufman, MD, Xiao J. Yan, MD, PhD, Emanuela M. Ghia, PhD, Donna Neuberg, ScD, Laura Z. Rassenti, Ph.D., Kostas Stamatopoulos, MD, Paolo Ghia, MD, PhD, David G Oscier, MD, Frederic Davi, MD, PhD, Richard Rosenquist, MD, PhD, Chrysoula Belessi, MD, Zadie Davis, PhD, Andreas Agathangelidis, Neil Kay, MD, John C. Byrd, MD, Jennifer R Brown, MD, PhD, Kanti R. Rai, M.D., Thomas J. Kipps, M.D., Ph.D, Nicholas Chiorazzi, M.D.

Blood (2011) 118 (21): 288.

https://doi.org/10.1182/blood.V118.21.288.288

Published: 2011

Journal Articles

Gene Set Enrichment Analysis of Ki-67 high CLL Clones Suggests Complex Interactions of B-Cell Receptor Signaling and Normal Cell Interactions in the Disease

Xiao J. Yan, MD, PhD, Daniel Kalenscher, Erin Boyle, Sophia Yancopoulos, PhD, Rajendra N Damle, PhD, Aarti Damle, Houman Khalili, Annette Lee, PhD, Wentian Li, Ph.D., Igor Dozmorov, MD, PhD, Matthew Kaufman, M.D., Peter Gregersen, MD, Steven L. Allen, M.D., Jonathan E. Kolitz, MD, Kanti R. Rai, MD, Nicholas Chiorazzi, M.D.

Blood (2011) 118 (21): 2833.

https://doi.org/10.1182/blood.V118.21.2833.2833

Published: 2011

Journal Articles

Combining Expression of Hypervariably Expressed Genes with IGHV Mutation Status Is a More Robust Prognostic Indicator Than Mutation Status Alone in Chronic Lymphocytic Leukemia

Blood (2011) 118 (21): 1774.

https://doi.org/10.1182/blood.V118.21.1774.1774

Published: 2011

Journal Articles

Improved Outcome of CLL Patients with Leukemic Clones Expressing Mutated IGHV May Not Be Due to An Inability to Bind (auto)Antigen In Vivo

Matthew Kaufman, Xiao-Jie Yan, M.D.;, Ph.D., Emanuela M. Ghia, PhD, Donna Neuberg, ScD, Laura Z Rassenti, PhD, Jennifer R Brown, MD, PhD, John C. Byrd, MD, Neil E. Kay, Kanti R Rai, MD, Thomas J. Kipps, MD, PhD, Nicholas Chiorazzi

Blood (2010) 116 (21): 2441.

https://doi.org/10.1182/blood.V116.21.2441.2441

Published: 2010

Journal Articles

Differential Expression Genes of CLL Subgroups Defined by Ki67 Expression Level Which Correlated with Clinical Outcome

Xiao-Jie Yan, M.D., Ph.D., Daniel Kalenscher, Erin Boyle, Arrti Damle, Sophie Yancopoulos, Ph.D., Rajendra N Damle, PhD, Houman Khalili, Annette Lee, PhD, Wentian Li, Ph.D., Igor Dozmorov, MD, PhD, Matthew Kaufman, M.D., Peter Gregersen, MD, Steven L. Allen, MD, Kanti R. Rai, MD, Nicholas Chiorazzi, M.D.

Blood (2010) 116 (21): 2435.

https://doi.org/10.1182/blood.V116.21.2435.2435

Published: 2010

Journal Articles

CCR4:CCL17 Interaction Influences TLR-9 Mediated Cell Survival and Proliferation In Chronic Lymphocytic Leukemia

Sonal C. Temburni, MS, Ryon M. Andersen, B.A., Luke Janson, B.A., Xiao-Jie Yan, MD;, Ph.D, Barbara Sherry, PhD, Matthew Kaufman, Steven L. Allen, MD, Kanti R. Rai, MD, Nicholas Chiorazzi, MD, Rajendra N. Damle, PhD

Blood (2010) 116 (21): 3593.

https://doi.org/10.1182/blood.V116.21.3593.3593

Published: 2010

Journal Articles

Efficacy and Safety of Hydroxychloroquine Sulphate In Chronic Lymphocytic Leukemia: Clinical Trial Experience In Untreated Patients

Shih-Shih Chen, Ph.D., Matthew Kaufman, M.D., Angelica Caramanica, Rajendra N Damle, Ph.D., Peter Garofalo, Patricia Ly, Dale Janson, Steven L. Allen, M.D., Jonathan Kolitz, M.D., Linda Quill, Kanti R. Rai, M.D., Nicholas Chiorazzi, M.D.

Blood (2010) 116 (21): 1392.

https://doi.org/10.1182/blood.V116.21.1392.1392

Published: 2010

Journal Articles

CD23 Receptor Positivity Has No Prognostic Implication in Chronic Lymphocytic Leukemia.

Jahan Aghalar, MD, Charles Chu, PhD, Rajendra N Damle, PhD, Che-Kai Tsao, MD, Nina Kohn, Matthew Kaufman, MD

Blood (2009) 114 (22): 4397.

https://doi.org/10.1182/blood.V114.22.4397.4397

Published: 2009

Journal Articles

Th-17/IL-17 Axis in Chronic Lymphocytic Leukemia.

Preetesh Jain, MBBS, MD, DM, Xiao J. Yan, MD, PhD, Mohammad Javdan, PhD, Pui Yan Chiu, MS, Rajendra N Damle, PhD, Tarush Kothari, MD, Steven L Allen, Matthew Kaufman, MD, Jonathan E. Kolitz, MD, Kanti R. Rai, MD, Nicholas Chiorazzi, MD, Barbara Sherry, PhD

Blood (2009) 114 (22): 2357.

https://doi.org/10.1182/blood.V114.22.2357.2357

Published: 2009

Journal Articles

Autologous Human T Cells and Allogeneic Antigen-Presenting Cells Permit Effective Adoptive Transfer of B-CLL Cells Into Immune Deficient Mice.

Davide Bagnara, PhD, Matthew Kaufman, MD, Carlo Calissano, MD, Sonia Marsilio, PhD, Philip Chum, Xiao J. Yan, MD, PhD, Peter K Gregersen, MD, Annette Lee, PhD, Kanti R Rai, MD, Nicholas Chiorazzi, MD

Blood (2009) 114 (22): 2326.

https://doi.org/10.1182/blood.V114.22.2326.2326

Published: 2009

Journal Articles

CCR4: TARC Interaction Provides Supplementary Pro-Survival and Proliferative Signals to Chronic Lymphocytic Leukemia Cells.

Rajendra N Damle, PhD, Sonal Temburni, Matthew Kaufman, MD, Jonathan E. Kolitz, MD, Steven L. Allen, Fabio Malavasi, MD, Kanti R. Rai, MD, Nicholas Chiorazzi, MD

Blood (2009) 114 (22): 2327.

https://doi.org/10.1182/blood.V114.22.2327.2327

Published: 2009

Journal Articles

Efficiency of BCR: Anti-BCR Interaction Dictates Cellular Outcomes of Signaling in Chronic Lymphocytic Leukemia Cells

Rajendra Damle, Sonal Temburni, Tara Schaaf, Santanu Paul, Patricia Mongini, Steven L. Allen, Matthew Kaufman, Kanti Rai, Nicholas Chiorazzi

Blood (2008) 112 (11): 3122.

https://doi.org/10.1182/blood.V112.11.3122.3122

Published: 2008

Journal Articles

A Human Hematopoietic Environment and Autologous T-Cell Growth Support Proliferation of Chronic Lymphocytic Leukemia B Cells in Immune-Deficient Mice

Davide Bagnara, Matthew Kaufman, Xiao J. Yan, MD, PhD, Kanti Rai, Nicholas Chiorazzi, MD

Blood (2008) 112 (11): 26.

https://doi.org/10.1182/blood.V112.11.26.26

Published: 2008

Journal Articles

p53 and COX-2 Inhibitors Control the Replication and Viability of Non-Transformed and CLL B Lymphocytes

Patricia Mongini, Ph.D., Matthew Kaufman, M.D., Jonathan E. Kolitz, MD, Steven L. Allen, M.D., Joshua Trott, Kanti Rai, M.D., Nicholas Chiorazzi, MD

Blood (2008) 112 (11): 3146.

https://doi.org/10.1182/blood.V112.11.3146.3146

Published: 2008

Journal Articles

Improved Prognosis of Chronic Lymphocytic Leukemia (CLL) Patients with Increased IgVH Mutations May Reflect Greater Alteration of the B-Cell Receptor (BCR) Binding Site

Matthew Kaufman, MD, Xiao Yan, MD, PhD, Rajendra Damle, PhD, Nina Kohn, MS, Martin Lesser, PhD, Nancy Driscoll, R-PA, Christina Johnson, R-PA, Jahan Aghalar, Yehuda Lebowicz, MD, Kanti Rai, MD, Nicholas Chiorazzi, MD

Blood (2008) 112 (11): 3152.

https://doi.org/10.1182/blood.V112.11.3152.3152

Published: 2008

Journal Articles

Activation of Nucleic Acid-Sensing Toll-Like Receptors Induces Proliferation, Cytokine Production, Immunogenic Phenotype, and Plasma Cell Differentiation of CLL Cells and Immunoglobulin Production.

Santanu Paul, PhD, Charles C. Chu, PhD, Brian A. McCarthy, PhD, Erin Boyle, BS, Bettie M. Steinberg, PhD, Matthew Kaufman, MD, Jonathan Kolitz, MD, Steven L. Allen, MD, Kanti R. Rai, MD, Nicholas Chiorazzi, MD

Blood (2007) 110 (11): 1137.

https://doi.org/10.1182/blood.V110.11.1137.1137

Published: 2007

Journal Articles

Response to Rituximab, Cyclophosphamide and Dexamethasone as Initial or Salvage Therapy in Low Grade Lymphoma and Immune Hemolytic Anemia.

Neetu Radhakrishnan, MD, Rajasree Roy, MD, Reuven Yakubov, MD, Matthew Kaufman, MD, Kanti Rai, MD, Bhoomi Mehrotra, MD, Dilip Patel, MD

Blood (2006) 108 (11): 4726.

https://doi.org/10.1182/blood.V108.11.4726.4726

Published: 2006

NARROW

Chronic Lymphocytic Leukemia Patients with IGHV Genes Carrying Only Silent Mutations Have A Longer Time From Diagnosis to Initial Therapy Than Patients Expressing B-Cell Receptors with No Somatic Mutations

Gene Set Enrichment Analysis of Ki-67 high CLL Clones Suggests Complex Interactions of B-Cell Receptor Signaling and Normal Cell Interactions in the Disease

Combining Expression of Hypervariably Expressed Genes with IGHV Mutation Status Is a More Robust Prognostic Indicator Than Mutation Status Alone in Chronic Lymphocytic Leukemia

Improved Outcome of CLL Patients with Leukemic Clones Expressing Mutated IGHV May Not Be Due to An Inability to Bind (auto)Antigen In Vivo

Differential Expression Genes of CLL Subgroups Defined by Ki67 Expression Level Which Correlated with Clinical Outcome

CCR4:CCL17 Interaction Influences TLR-9 Mediated Cell Survival and Proliferation In Chronic Lymphocytic Leukemia

Efficacy and Safety of Hydroxychloroquine Sulphate In Chronic Lymphocytic Leukemia: Clinical Trial Experience In Untreated Patients

CD23 Receptor Positivity Has No Prognostic Implication in Chronic Lymphocytic Leukemia.

Th-17/IL-17 Axis in Chronic Lymphocytic Leukemia.

Autologous Human T Cells and Allogeneic Antigen-Presenting Cells Permit Effective Adoptive Transfer of B-CLL Cells Into Immune Deficient Mice.

CCR4: TARC Interaction Provides Supplementary Pro-Survival and Proliferative Signals to Chronic Lymphocytic Leukemia Cells.

Efficiency of BCR: Anti-BCR Interaction Dictates Cellular Outcomes of Signaling in Chronic Lymphocytic Leukemia Cells

A Human Hematopoietic Environment and Autologous T-Cell Growth Support Proliferation of Chronic Lymphocytic Leukemia B Cells in Immune-Deficient Mice

p53 and COX-2 Inhibitors Control the Replication and Viability of Non-Transformed and CLL B Lymphocytes

Improved Prognosis of Chronic Lymphocytic Leukemia (CLL) Patients with Increased IgVH Mutations May Reflect Greater Alteration of the B-Cell Receptor (BCR) Binding Site

Activation of Nucleic Acid-Sensing Toll-Like Receptors Induces Proliferation, Cytokine Production, Immunogenic Phenotype, and Plasma Cell Differentiation of CLL Cells and Immunoglobulin Production.

Response to Rituximab, Cyclophosphamide and Dexamethasone as Initial or Salvage Therapy in Low Grade Lymphoma and Immune Hemolytic Anemia.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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