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Matthew C. Stubbs, PhD
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Journal Articles

Characterization of INCB00928, a Potent and Selective ALK2 Inhibitor for the Treatment of Anemia

Yaoyu Chen, Matthew C. Stubbs, PhD, Michelle Pusey, Xiaoming Wen, Robert J. Collins, Kanishk Kapilashrami, Mark Rupar, Pramod Thekkat, Luping Lin, PhD, Kevin Bowman, Yan-ou Yang, Sharon Diamond, Swamy Yeleswaram, PhD, Sunkyu Kim, Holly K. Koblish, PhD, Yingnan Chen, Susan Wee, PhD BS
Journal: Blood
Blood (2020) 136 (Supplement 1): 52.
https://doi.org/10.1182/blood-2020-136138
Published: 2020
Journal Articles

Nascent Transcript and Single Cell Rnaseq Analysis Defines the Mechanism of Action of the LSD1 Inhibitor INCB059872 in Myeloid Leukemia

Gretchen Johnston, Haley E. Ramsey, PhDMSc, Kristy Stengel, PhD, Shilpa Sampathi, PhD, Pankaj Acharya, PhD, Maria Arrate, MSc, Matthew C. Stubbs, PhD, Timothy Burn, PhD, Scott Hiebert, PhD, Michael R. Savona, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2509.
https://doi.org/10.1182/blood-2019-130458
Published: 2019
Journal Articles

The BET Inhibitor INCB054329 Primes AML Cells for Venetoclax-Induced Apoptosis

Haley Ramsey, PhD MSc, Susu Zhang, Yue Zhao, PhD, Melissa Ann Fischer, PhD, Agnieszka Ewa Gorska, MSc, Maria Arrate, MSc, Londa Fuller, Dalton Greenwood, Matthew C. Stubbs, PhD, Phillip Liu, PhD, Jeffrey C Rathmell, PhD, Scott Hiebert, PhD, Michael R. Savona, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4074.
https://doi.org/10.1182/blood-2018-99-111393
Published: 2018
Journal Articles

Selective Inhibition of HDAC1 and HDAC2 Is a Potential Therapeutic Option for B-All

Matthew C. Stubbs, PhD, Won-Il Kim, Ph.D., Tina Davis, Jun Qi, Ph.D., James Bradner, M.D., Andrew L. Kung, MD, PhD, Scott A. Armstrong, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2900.
https://doi.org/10.1182/blood.V116.21.2900.2900
Published: 2010
Journal Articles

Cell of Origin Influences Leukemia Stem Cell Phenotype.

Andrei V. Krivtsov, PhD, Amit U. Sinha, Matthew C. Stubbs, PhD, Andrew Kung, MD, PhD, Scott Armstrong, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 3459.
https://doi.org/10.1182/blood.V114.22.3459.3459
Published: 2009
Journal Articles

The Myocyte Enhancer Factor 2C ( MEF2C ) Is a Direct Transcriptional Target of HOXA9 and Mediates Leukemia Survival in Human Mixed-Lineage Leukemias.

Jorg Faber, MD, PhD, Andrei V. Krivstov, PhD, Matthew C. Stubbs, PhD, Marry van den Heuvel-Eibrink, MD, PhD, Andrew L. Kung, MD, PhD, Christian M. Zwaan, MD, PhD, Scott A. Armstrong, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 58.
https://doi.org/10.1182/blood.V110.11.58.58
Published: 2007
Journal Articles

HOXA9 Represses Bim Expression in MLL Rearranged Leukemia: Implications for Drug Therapy.

Matthew C. Stubbs, PhD, Joerg Faber, M.D., Ph.D., Andrew L. Kung, M.D., Ph.D., Scott Cameron, M.D., Ph.D., Scott A. Armstrong, M.D., Ph.D.
Journal: Blood
Blood (2007) 110 (11): 57.
https://doi.org/10.1182/blood.V110.11.57.57
Published: 2007
Journal Articles

MLL-AF9 Initiates Leukemia from a Single Committed Hematopoietic Progenitor.

Andrei V. Krivtsov, PhD, Matthew C. Stubbs, PhD, Renee Wright, Zhaohui Feng, Andrew L. Kung, MD,PhD, Scott A. Armstrong, MD,PhD
Journal: Blood
Blood (2006) 108 (11): 2534.
https://doi.org/10.1182/blood.V108.11.2534.2534
Published: 2006
Journal Articles

Induction of Bim Facilitates Apoptosis in Leukemia Cells Treated with HDAC Inhibitors.

Matthew C. Stubbs, PhD, Teresa Kim, Andrei Krivtsov, Ph.D., Peter Atadja, Scott A. Armstrong, M.D., Ph.D., Andrew L. Kung, M.D., Ph.D.
Journal: Blood
Blood (2006) 108 (11): 1994.
https://doi.org/10.1182/blood.V108.11.1994.1994
Published: 2006
Journal Articles

HoxA9 Knockdown Inhibits Proliferation and Induces Cell Death in Human MLL-Rearranged Leukemias.

Jorg Faber, MD, PhD, Andrei V. Krivtsov, PhD, Matthew C. Stubbs, PhD, Renee Wright, Marry van den Heuvel-Eibrink, MD PhD, Andrew L. Kung, MD PhD, Christian M. Zwaan, MD PhD, Scott A. Armstrong, MD PhD
Journal: Blood
Blood (2006) 108 (11): 734.
https://doi.org/10.1182/blood.V108.11.734.734
Published: 2006
Journal Articles

MLL -Fusion Proteins Induce a Stem Cell Program in Committed Progenitors To Generate Leukemia Stem Cells.

Andrei V. Krivstov, PhD, David Twomey, Zhaohui Feng, Matthew C. Stubbs, PhD, Todd R. Golub, MD, Scott A. Armstrong, MD, PhD.
Journal: Blood
Blood (2005) 106 (11): 465.
https://doi.org/10.1182/blood.V106.11.465.465
Published: 2005
Journal Articles

MLL-AF9 and FLT3 Cooperation during Myeloid Leukemogenesis: Development of a Model for Rapid Testing of New Therapeutics.

Matthew C. Stubbs, PhD, Andrei Krivtsov, PhD, Yong-mi Kim, MD, Renee D. Wright, Zhaohui Feng, Jyoti Agarwal, Andrew L. Kung, MD, PhD, Scott A. Armstrong, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 1605.
https://doi.org/10.1182/blood.V106.11.1605.1605
Published: 2005