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Journal Articles

Targeting Cks1b in Multiple Myeloma Using Fluoxetine

Alice Worker, Dean Smith, Martin Grundy, Joanne Lindsey-Hill, Tanatswa Makore, Mark J Bishton, Claire Seedhouse

Blood (2024) 144 (Supplement 1): 6811.

https://doi.org/10.1182/blood-2024-194791

Published: 2024

Journal Articles

Comparison of Two Rapid Predictive Methods for Therapeutic Targeting in Acute Myeloid Leukaemia Cells

Martin Grundy, PhD, Jones Thomas, BSc, Liban Elmi, B MDSci, Michael Hall, B MDSci, Nigel H Russell, MD, Monica Pallis, PhD

Blood (2016) 128 (22): 1704.

https://doi.org/10.1182/blood.V128.22.1704.1704

Published: 2016

Journal Articles

Analysis of the Interaction of Induction Regimens with P-Glycoprotein Expression In Patients with Acute Myeloid Leukaemia: Results From the MRC AML15 Trial

Monica Pallis, PhD, Paul White, PhD, Robert Hills, MA, MSc, DPhil, Martin Grundy, BSc, Nigel H. Russell, MD, Alan Burnett

Blood (2010) 116 (21): 2724.

https://doi.org/10.1182/blood.V116.21.2724.2724

Published: 2010

Journal Articles

RHPS4, An Anti-Telomere Agent, Specifically Targets the Subgroup of AML Cells with Loss or Gain of Parts of Chromosomes.

Monica Pallis, PhD, Simone Clarke, Martin Grundy, BSc, Jaineeta Richardson, Dotun Ojo, Susan Anderson, Nigel H. Russell, MD, Claire Seedhouse

Blood (2010) 116 (21): 1195.

https://doi.org/10.1182/blood.V116.21.1195.1195

Published: 2010

Journal Articles

A Polymorphism In the 3'UTR Region of ABCB1 Is Associated with Increased Allele Activity with Corresponding Increases In P-Glycoprotein Expression and Function

Nada Bajuaifer, Martin Grundy, BSc, Robert Hills, MA, MSc, DPhil, Nigel H. Russell, MD, Monica Pallis, PhD, Claire Seedhouse

Blood (2010) 116 (21): 3990.

https://doi.org/10.1182/blood.V116.21.3990.3990

Published: 2010

Journal Articles

Impaired S Phase Arrest in AML Cells with a FLT3-ITD Treated with Clofarabine Allows Prolonged Drug exposure to Reverse the Chemoresistant Phenotype.

Claire Seedhouse, PhD, Martin Grundy, BSc, Shili Shang, MD, MSc, John Ronan, CSci, FIBMS, Heather Pimblett, Nigel H. Russell, MD, Monica Pallis, PhD

Blood (2009) 114 (22): 1000.

https://doi.org/10.1182/blood.V114.22.1000.1000

Published: 2009

Journal Articles

Regulation of ABCB1 (p-glycoprotein) by the FOXO1 Transcription Factor in Acute Myeloid Leukemia.

Claire Seedhouse, PhD, Sophie Ahluwalia, BSc, Ken I Mills, Ph.D., FRCPath, Martin Grundy, BSc, Shili Shang, MD, MSc, Alan K. Burnett, MD, FRCP, Nigel H. Russell, MD, Monica Pallis, PhD

Blood (2009) 114 (22): 589.

https://doi.org/10.1182/blood.V114.22.589.589

Published: 2009

Journal Articles

The Effect of ABC Transporters and FLT3 Status on the Activity of the Aurora Kinase B Inhibitor AZD1152 in AML Cells.

Martin Grundy, BSc, Shili Shang, MD, MSc, C. Seedhouse, PhD, Nigel H. Russell, MD, Monica Pallis, PhD

Blood (2008) 112 (11): 1627.

https://doi.org/10.1182/blood.V112.11.1627.1627

Published: 2008

Journal Articles

A Stat5b transgene is capable of inducing CD8 + lymphoblastic lymphoma in the absence of normal TCR/MHC signaling

Katherine Bessette, Mark L. Lang, Roy A. Fava, Martin Grundy, Jennifer Heinen, Laurie Horne, Rosanne Spolski, Amin Al-Shami, Herbert C. Morse, III, Warren J. Leonard, John A. Kelly

Blood (2008) 111 (1): 344–350.

https://doi.org/10.1182/blood-2007-04-084707

Published: 2008

Includes: Supplemental data

Journal Articles

P-Glycoprotein Is Downregulated in KG1a Primitive Leukaemia Cells by LDL Cholesterol Deprivation and by HMG-CoA Reductase Inhibitors.

Laura Connelly-Smith, MBBCh, Joanne Pattinson, Martin Grundy, Shili Shang, Claire Seedhouse, PhD, Nigel Russell, MBChB, Monica Pallis, PhD

Blood (2007) 110 (11): 4192.

https://doi.org/10.1182/blood.V110.11.4192.4192

Published: 2007

Journal Articles

A Role for DNA Double Strand Breaks in the Sensitivity of AML Cells to Clofarabine: Enhanced In Vitro Sensitivity in Primary AML Cells with FLT3 Mutations.

Monica Pallis, PhD, Martin Grundy, BSc, Claire Seedhouse, PhD, Heather Pimblett, B Med Sci, Nigel Russell, MD

Blood (2006) 108 (11): 2582.

https://doi.org/10.1182/blood.V108.11.2582.2582

Published: 2006

Journal Articles

Increasing FLT3-ITD Length Increases Expression of bcl-xl in AML.

Claire H. Seedhouse, PhD, Monica Pallis, PhD, Martin Grundy, BSc, Nigel Russell, MD

Blood (2006) 108 (11): 1909.

https://doi.org/10.1182/blood.V108.11.1909.1909

Published: 2006

Journal Articles

Competing Influences of Genetic and Leukaemia-Specific Factors on P-Glycoprotein Expression in Blasts from 817 Patients Entered into the NCRN AML14 and 15 Trials.

Claire H. Seedhouse, PhD, Martin Grundy, BSc, Paul White, PhD, Yun Li, MSc, Janet Fisher, BSc, Darya Yakunina, MD, Anthony Moorman, PhD, Nigel Russell, MD, Alan Burnett, MD, Monica Pallis, PhD

Blood (2006) 108 (11): 835.

https://doi.org/10.1182/blood.V108.11.835.835

Published: 2006

Journal Articles

Reproducible measurements of AML blast p-glycoprotein function in 2 center analyses

Monica Pallis, Janet Fisher, Louise Truran, Martin Grundy, Nigel Russell, Alan Burnett

Blood (2005) 105 (3): 1367–1368.

https://doi.org/10.1182/blood-2004-08-3303

Published: 2005

Journal Articles

P-Glycoprotein Overexpresion and Internal Tandem Duplications of FLT3 Are Characteristic of Discrete Populations of Elderly AML Patients.

Monica Pallis, PhD, Louise Truran, B Sc, Martin Grundy, B Sc, Janet Fisher, M Sc, Robert Hills, PhD, Keith Wheatley, PhD, Nigel Russell, MD, Alan Burnett, MD

Blood (2004) 104 (11): 196.

https://doi.org/10.1182/blood.V104.11.196.196

Published: 2004

Journal Articles

Mitochondrial membrane sensitivity to depolarization in acute myeloblastic leukemia is associated with spontaneous in vitro apoptosis, wild-type TP53, and vicinal thiol/disulfide status

Monica Pallis, Martin Grundy, Julie Turzanski, Reinhard Kofler, Nigel Russell

Blood (2001) 98 (2): 405–413.

https://doi.org/10.1182/blood.V98.2.405

Published: 2001

NARROW

Targeting Cks1b in Multiple Myeloma Using Fluoxetine

Comparison of Two Rapid Predictive Methods for Therapeutic Targeting in Acute Myeloid Leukaemia Cells

Analysis of the Interaction of Induction Regimens with P-Glycoprotein Expression In Patients with Acute Myeloid Leukaemia: Results From the MRC AML15 Trial

RHPS4, An Anti-Telomere Agent, Specifically Targets the Subgroup of AML Cells with Loss or Gain of Parts of Chromosomes.

A Polymorphism In the 3'UTR Region of ABCB1 Is Associated with Increased Allele Activity with Corresponding Increases In P-Glycoprotein Expression and Function

Impaired S Phase Arrest in AML Cells with a FLT3-ITD Treated with Clofarabine Allows Prolonged Drug exposure to Reverse the Chemoresistant Phenotype.

Regulation of ABCB1 (p-glycoprotein) by the FOXO1 Transcription Factor in Acute Myeloid Leukemia.

The Effect of ABC Transporters and FLT3 Status on the Activity of the Aurora Kinase B Inhibitor AZD1152 in AML Cells.

A Stat5b transgene is capable of inducing CD8 + lymphoblastic lymphoma in the absence of normal TCR/MHC signaling

P-Glycoprotein Is Downregulated in KG1a Primitive Leukaemia Cells by LDL Cholesterol Deprivation and by HMG-CoA Reductase Inhibitors.

A Role for DNA Double Strand Breaks in the Sensitivity of AML Cells to Clofarabine: Enhanced In Vitro Sensitivity in Primary AML Cells with FLT3 Mutations.

Increasing FLT3-ITD Length Increases Expression of bcl-xl in AML.

Competing Influences of Genetic and Leukaemia-Specific Factors on P-Glycoprotein Expression in Blasts from 817 Patients Entered into the NCRN AML14 and 15 Trials.

Reproducible measurements of AML blast p-glycoprotein function in 2 center analyses

P-Glycoprotein Overexpresion and Internal Tandem Duplications of FLT3 Are Characteristic of Discrete Populations of Elderly AML Patients.

Mitochondrial membrane sensitivity to depolarization in acute myeloblastic leukemia is associated with spontaneous in vitro apoptosis, wild-type TP53, and vicinal thiol/disulfide status

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American Society of Hematology

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ASH Publications

American Society of Hematology

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