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Journal Articles

Regulation of ABCB1 (p-glycoprotein) by the FOXO1 Transcription Factor in Acute Myeloid Leukemia.

Claire Seedhouse, PhD, Sophie Ahluwalia, BSc, Ken I Mills, Ph.D., FRCPath, Martin Grundy, BSc, Shili Shang, MD, MSc, Alan K. Burnett, MD, FRCP, Nigel H. Russell, MD, Monica Pallis, PhD
Journal: Blood
Blood (2009) 114 (22): 589.
https://doi.org/10.1182/blood.V114.22.589.589
Published: 2009
Journal Articles

Impaired S Phase Arrest in AML Cells with a FLT3-ITD Treated with Clofarabine Allows Prolonged Drug exposure to Reverse the Chemoresistant Phenotype.

Claire Seedhouse, PhD, Martin Grundy, BSc, Shili Shang, MD, MSc, John Ronan, CSci, FIBMS, Heather Pimblett, Nigel H. Russell, MD, Monica Pallis, PhD
Journal: Blood
Blood (2009) 114 (22): 1000.
https://doi.org/10.1182/blood.V114.22.1000.1000
Published: 2009
Journal Articles

The Effect of ABC Transporters and FLT3 Status on the Activity of the Aurora Kinase B Inhibitor AZD1152 in AML Cells.

Martin Grundy, BSc, Shili Shang, MD, MSc, C. Seedhouse, PhD, Nigel H. Russell, MD, Monica Pallis, PhD
Journal: Blood
Blood (2008) 112 (11): 1627.
https://doi.org/10.1182/blood.V112.11.1627.1627
Published: 2008
Journal Articles

P-Glycoprotein Is Downregulated in KG1a Primitive Leukaemia Cells by LDL Cholesterol Deprivation and by HMG-CoA Reductase Inhibitors.

Laura Connelly-Smith, MBBCh, Joanne Pattinson, Martin Grundy, Shili Shang, Claire Seedhouse, PhD, Nigel Russell, MBChB, Monica Pallis, PhD
Journal: Blood
Blood (2007) 110 (11): 4192.
https://doi.org/10.1182/blood.V110.11.4192.4192
Published: 2007
Journal Articles

Interactions of Midostaurin (PKC412), Rapamycin and Ara-C in AML Cell Lines: Role of FLT3 Signalling.

Claire H. Seedhouse, PhD, Shili Shang, MSc, Nigel Russell, MD, Emma Das-Gupta, MD
Journal: Blood
Blood (2007) 110 (11): 2841.
https://doi.org/10.1182/blood.V110.11.2841.2841
Published: 2007