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Martin FM de Rooij
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Journal Articles

Combined Inhibition of Phosphatidylinositol 3-Kinase (PI3K) Isoform α and δ By the Pan-Class I PI3K Inhibitor SAR245409 (XL765) in Primary Chronic Lymphocytic Leukemia Cells Blocks Survival, Adhesion and Proliferation

Rachel Thijssen, Gregor van Bochove, Martin FM de Rooij, Johanna ter Burg, Marcel Spaargaren, PhD, Coumaran Egile, PhD, Marie Jose Kersten, MD PhD, Eric Eldering, PhD, Arnon P. Kater, MD PhD
Journal: Blood
Blood (2014) 124 (21): 4691.
https://doi.org/10.1182/blood.V124.21.4691.4691
Published: 2014
Journal Articles

Combined Inhibition of mTOR and DNA-PK Blocks Survival, Adhesion, Proliferation and Chemoresistance in Primary Chronic Lymphocytic Leukemia (CLL) Cells

Rachel Thijssen, Gregor van Bochove, Ingrid AM Derks, Johanna ter Burg, Martin FM de Rooij, Marcel Spaargaren, PhD, Marie Jose Kersten, MD PhD, Eric Eldering, PhD, Arnon P. Kater, MD PhD
Journal: Blood
Blood (2014) 124 (21): 1981.
https://doi.org/10.1182/blood.V124.21.1981.1981
Published: 2014
Journal Articles

Possible Mechanisms Of Resistance To The Novel BH3-Mimetic ABT-199 In In Vitro Lymph Node Models Of CLL – The Role Of Abl and Btk

Rachel Thijssen, Christian R Geest, Martin FM de Rooij, Nora Liu, Bogdan I Florea, Katinka Weller, Hermen S Overkleeft, Marinus H.J. Van Oers, MD, PhD, Marcel Spaargaren, PhD, Arnon P. Kater, MD PhD, Eric Eldering, PhD
Journal: Blood
Blood (2013) 122 (21): 4188.
https://doi.org/10.1182/blood.V122.21.4188.4188
Published: 2013
Journal Articles

Mapping the Targets of Dasatinib in Chronic Lymphocytic Leukemia Reveals Distinct Roles for Abl and Btk in Drug Resistance and Adhesion, and Explains Clinical Effects On Lymph Node Reduction

Eric Eldering, PhD, Christian R Geest, Martin FM de Rooij, Nora Liu, Bogdan I Florea, Marinus H.J. Van Oers, MD, PhD, Hermen S Overkleeft, Marcel Spaargaren, PhD, Arnon P. Kater, MD PhD
Journal: Blood
Blood (2012) 120 (21): 3900.
https://doi.org/10.1182/blood.V120.21.3900.3900
Published: 2012