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Mark T Gladwin, MD
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Journal Articles

Impaired Hepcidin Metabolism Promotes Hemolysis Induced Hepatobiliary Injury in Sickle Cell Disease

Ravi Vats, MSc, Enrico M Novelli, MD, M.S., Prithu Sundd, PhD, Mark T Gladwin, MD, Tirthadipa Pradhan
Journal: Blood
Blood (2020) 136 (Supplement 1): 28.
https://doi.org/10.1182/blood-2020-143357
Published: 2020
Journal Articles

Exercise Induced Changes of Vital Signs in Adults with Sickle Cell Disease

Solomon Johnson, MS, Victor R. Gordeuk, MD, Roberto Machado, MD, J Simon R Gibbs, Mariana Hildesheim, MS, Jane A. Little, MD, Gregory J Kato, MD, Mark T Gladwin, MD, Seyed Mehdi Nouraie, PhD MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 59–60.
https://doi.org/10.1182/blood-2020-136393
Published: 2020
Journal Articles

The T117S Variant of Cytochrome b5 Reductase 3 Increases the Risk for Ischemic Stroke with Enhanced Anemia in Mice with Sickle Cell Disease

Katherine C Wood, PhD, Heidi M Schmidt, Scott Hahn, MS, Subramaniam Sanker, PhD, Samit Ghosh, PhD, Solomon Fiifi Ofori-Acquah, PhD, Seyed Mehdi Nouraie, MD PhD, Mark T Gladwin, MD, Adam C Straub, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17–18.
https://doi.org/10.1182/blood-2020-142076
Published: 2020
Journal Articles

Integrin αIIbβ3 Regulates Platelet-Procoagulant Activity in the Lung

Tomasz Brzoska, PhD, Tomasz W. Kaminski, PharmD, Ravi Vats, MSc, Egemen Tutuncuoglu, MSc, Mark T Gladwin, MD, Prithu Sundd, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 32.
https://doi.org/10.1182/blood-2020-142503
Published: 2020
Journal Articles

Genome Wide Association Analysis of Iron Overload in the Trans-Omics for Precision Medicine (TOPMed) Sickle Cell Disease Cohorts

Fayuan Wen, PhD, Angela Rock, Juan Salomon-Andonie, MS, Gulriz Kurban, PhD, Xiaomei Niu, MD, Songping Wang, Xu Zhang, PhD, Victor R. Gordeuk, MD, Yingze Zhang, PhD, Seyed Mehdi Nouraie, PhD MD, Mark T Gladwin, MD, Allison Ashley-Koch, PhD, Marilyn J. Telen, MD, Brian Custer, PhD, Shannon Kelly, Carla Luana Dinardo, PhD, Ester Sabino, Quenna Wong, James G. Taylor, MD, Sergei Nekhai, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 52.
https://doi.org/10.1182/blood-2020-142809
Published: 2020
Journal Articles

Loss of FXR Signaling Promotes Chronic Liver Injury in Sickle Cell Disease

Ravi Vats, MSc, Enrico M Novelli, MD, M.S., Mark T Gladwin, MD, Prithu Sundd, PhD, Tirthadipa Pradhan
Journal: Blood
Blood (2020) 136 (Supplement 1): 16.
https://doi.org/10.1182/blood-2020-143330
Published: 2020
Journal Articles

Circulating Neutrophil Extracellular Traps in the Pathogenesis of Acute Chest Syndrome of Sickle Cell Disease

Ravi Vats, MSc, Egemen Tutuncuoglu, MSc, Jesus Tejero, PhD, Cheryl A Hillery, MD, Mark T Gladwin, MD, Prithu Sundd, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3556.
https://doi.org/10.1182/blood-2019-130574
Published: 2019
Journal Articles

Smooth Muscle Cytochrome b5 Reductase 3 Deficiency Accelerates Pulmonary Hypertension Development in Sickle Cell Mice

Katherine Wood, PhD BA, Brittany Durgin, PhD, Heidi M Schmidt, BSE, Scott Hahn, Jeffrey Baust, Tim Bachman, Dario A. Vitturi, PhD, Samit Ghosh, Solomon Fiifi Ofori-Acquah, Ana Mora, MD, Mark T Gladwin, MD, Adam Straub, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3619.
https://doi.org/10.1182/blood-2019-124159
Published: 2019
Journal Articles

Impaired Bile Secretion Promotes Chronic Liver Injury in Sickle Cell Disease

Tirthadipa Pradhan, Prithu Sundd, PhD, Mark T Gladwin, MD, Satdarshan Pal Monga, Gregory J Kato, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3536.
https://doi.org/10.1182/blood-2019-131915
Published: 2019
Journal Articles

CD39 As a Master Regulator of Pulmonary Thrombosis in Sickle Cell Disease

Tomasz Brzoska, PhD, Egemen Tutuncuoglu, MSc, Stevan P. Tofovic, Edwin K. Jackson, Mark T Gladwin, MD, Prithu Sundd, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2266.
https://doi.org/10.1182/blood-2019-130882
Published: 2019
Journal Articles

Manifestations of Reduced Kidney Function Occur at a Higher Estimated Glomerular Filtration Rate in Sickle Cell Anemia

Santosh L. Saraf, MD, Vimal K. Derebail, MD, Xu Zhang, PhD, Mark T Gladwin, MD, Victor R Gordeuk, MD, Jane A. Little, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2268.
https://doi.org/10.1182/blood-2019-124737
Published: 2019
Journal Articles

Risk Factors for Kidney Disease in Hb SC and Hb Sβ + -Thalassemia Sickle Cell Disease

Mandella Mensah, Binal N. Shah, Xu Zhang, PhD, Jin Han, PharmD, PhD, Michel Gowhari, DO, Robert E. Molokie, MD, Mark T Gladwin, MD, Victor R Gordeuk, MD, Santosh L. Saraf, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2299.
https://doi.org/10.1182/blood-2019-128668
Published: 2019
Journal Articles

Innate Immune Mechanism of Hemarthrosis in Hemophilia-a Mice

Tomasz W. Kaminski, PharmD, Egemen Tutuncuoglu, MSc, Margaret V. Ragni, MD MPH, Mark T Gladwin, MD, Prithu Sundd, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1043.
https://doi.org/10.1182/blood-2019-130471
Published: 2019
Journal Articles

Sickle Cell Disease Promotes Dysregulation of Hepatic Iron Homeostasis By Regulating Hepcidin Expression

Tirthadipa Pradhan, Prithu Sundd, PhD, Satdarshan Pal Monga, Mark T Gladwin, MD, Gregory J Kato, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 958.
https://doi.org/10.1182/blood-2019-131921
Published: 2019
Journal Articles

Evaluation of the Functional Effects of an African American Glucose-6-Phosphate Dehydrogenase (G6PD) Polymorphism (Val68Met) on RBC Hemolytic Propensity and Post-Transfusion Recovery in a Humanized Mouse Model

Ling Wang, MD PhD, Benjamin Zuchelkowski, Derek Sinchar, Minying Yang, Sebastien Gingras, Tamir Kanias, PhD, Janet S Lee, Daniel Kim-Shapiro, Grier Page, PhD BS, MS, Mark T Gladwin, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 102.
https://doi.org/10.1182/blood-2019-124926
Published: 2019
Journal Articles

Mechanism of Pulmonary Thrombosis in Hemolytic Disorders

Tomasz Brzoska, PhD, Margaret F. Bennewitz, PhD, Egemen Tutuncuoglu, MSc, Margaret V. Ragni, MD MPH, Matthew D Neal, MD, Mark T Gladwin, MD, Prithu Sundd, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 976.
https://doi.org/10.1182/blood-2019-130592
Published: 2019
Journal Articles

Clinical and Laboratory Predictors of 30-Day Hospital Readmission Risk in Adult Patients with Sickle Cell Disease

Seyed Mehdi Nouraie, PhD MD, Melissa Saul, MS, Enrico M Novelli, MD MS, Gregory J. Kato, MD, Mark T Gladwin, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2384.
https://doi.org/10.1182/blood-2018-99-115248
Published: 2018
Journal Articles

Soluble Guanylate Cyclase Modulators Effect Fetal Hemoglobin Levels through a Non-cGMP-Protein Kinase G Signaling Pathway

Bin Sun, PhD, Valerie Miller, MS, Karin P Potoka, MD, Yukio Nakamura, MD PhD, Mark T Gladwin, MD, Grant C. Bullock, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1060.
https://doi.org/10.1182/blood-2018-99-120306
Published: 2018
Journal Articles

Regulatory Genetic Variation at the S100B Gene Associates with Vaso-Occlusive Manifestations in Sickle Cell Disease

Xu Zhang, PhD, Wei Zhang, PhD, Santosh L. Saraf, MD, Sergei Nekhai, PhD, Mark T Gladwin, MD, Roberto Machado, Victor R. Gordeuk, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1063.
https://doi.org/10.1182/blood-2018-99-115395
Published: 2018
Journal Articles

Biomarker Signatures of Sickle Cell Disease Severity

Mengtian Du, BA, Sarah Van Ness, BA, Victor R. Gordeuk, MD, Mark T Gladwin, MD, Paola Sebastiani, PhD, Martin H. Steinberg, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 690.
https://doi.org/10.1182/blood.V130.Suppl_1.690.690
Published: 2017