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Journal Articles

Non-Glycolytic Role of the Myeloid Hexokinase 3 (HK3) in Therapy Responses of Myeloid Malignancies

Kristina Seiler, Mario P. Tschan, Carmen Kalbermatter, Tanja Muralt, Tata Nageswara Rao, Bruce E. Torbett

Blood (2022) 140 (Supplement 1): 5883.

https://doi.org/10.1182/blood-2022-157499

Published: 2022

Journal Articles

ULK1 Blockade Preferentially Targets Germinal Centre B-Cell - Diffuse Large B-Cell Lymphoma Subtype By Attenuating Autophagy, c-MYC and Inflammation

Harpreet Mandhair, Ramin Radpour, Andrew Davies, Mario P. Tschan, Urban Novak

Blood (2022) 140 (Supplement 1): 9296–9297.

https://doi.org/10.1182/blood-2022-169004

Published: 2022

Journal Articles

The Transcription Factor PU.1 Controls Alternative Splicing of Cflip By Binding to SRSF2/10 Splice Factors in AML Therapy Responses

Nicolas Niklaus, Magali Humbert, Bruce E. Torbett, Mario P. Tschan

Blood (2022) 140 (Supplement 1): 8742–8743.

https://doi.org/10.1182/blood-2022-157921

Published: 2022

Journal Articles

Characterization of Bypassing Kinases Inferred By Phosphoproteomics in a Midostaurin Resistant Myeloid Cell Line Model

Mahmoud Hallal, BSc, MSc, Sophie Braga-Lagache, MSc, Jovana Jankovic, Rémy Bruggmann, PhD, Ramanjaneyulu Allam, PhD MSc, BSc, Mario P. Tschan, PhD, Cédric Simillion, PhD, Manfred Heller, PhD, Nicolas Bonadies, MD

Blood (2019) 134 (Supplement_1): 2079.

https://doi.org/10.1182/blood-2019-122337

Published: 2019

Journal Articles

Elucidating the Non-Catalytic Function of Fatty Acid Synthase and Its Autophagy-Dependent Degradation in Acute Myelocytic Leukemia Differentiation Therapy

Magali Humbert, PhD, Severin Mosimann, Vreni Rentsch, Mario P. Tschan, PhD

Blood (2018) 132 (Supplement 1): 2624.

https://doi.org/10.1182/blood-2018-99-112068

Published: 2018

Journal Articles

Hexokinase Proteins Impart Distinct Functions in Myeloid Development and Cell Death

Kristina Seiler, MD, Petra Minder, PhD, Iris Mashimo, Magali Humbert, PhD, Elizabeth Simpson, Mario P. Tschan, PhD, Bruce E. Torbett, PhD

Blood (2018) 132 (Supplement 1): 5088.

https://doi.org/10.1182/blood-2018-99-112145

Published: 2018

Journal Articles

A Novel PU.1 - Caspase 8/cFLIP Axis in Neutrophil and Macrophage Differentiation of AML Cells

Magali Humbert, PhD, Mario P. Tschan, PhD, Aladin Haimovici, Bruce E. Torbett, PhD, Nicolas Niklaus, MSc, BSc

Blood (2018) 132 (Supplement 1): 1347.

https://doi.org/10.1182/blood-2018-99-112797

Published: 2018

Journal Articles

Dissecting the Autophagy Tumor Suppressor Pathway Network in Acute Promyelocytic Leukemia Therapy

Magali Humbert, PhD, Elena Federzoni, Mario P. Tschan, PhD

Blood (2016) 128 (22): 1560.

https://doi.org/10.1182/blood.V128.22.1560.1560

Published: 2016

Journal Articles

Non-Canonical Autophagy during APL Therapy

Jing Jin, PhD, Magali Humbert, PhD, Mario P. Tschan, PhD

Blood (2016) 128 (22): 1621.

https://doi.org/10.1182/blood.V128.22.1621.1621

Published: 2016

Journal Articles

PU.1 is linking the glycolytic enzyme HK3 in neutrophil differentiation and survival of APL cells

Elena A. Federzoni, Peter J. M. Valk, Bruce E. Torbett, Torsten Haferlach, Bob Löwenberg, Martin F. Fey, Mario P. Tschan

Blood (2012) 119 (21): 4963–4970.

https://doi.org/10.1182/blood-2011-09-378117

Published: 2012

Includes: Supplemental data

Journal Articles

Inhibition of Key Autophagy Genes in Primary AML Patients and Their Functional Role in Neutrophil Differentiation of APL Cells

Mario P. Tschan, PhD, Daniel Brigger, M.Sc., Anna M. Schläfli, M.Sc., Martin F. Fey, MD

Blood (2011) 118 (21): 2456.

https://doi.org/10.1182/blood.V118.21.2456.2456

Published: 2011

Journal Articles

Linking the Glycolytic Enzyme HK3 to Neutrophil Differentiation of APL Cells Via PU.1

Elena A. Federzoni, M.Sc., Peter Valk, Bob Löwenberg, MD, Martin F. Fey, MD, Mario P. Tschan, PhD

Blood (2011) 118 (21): 2425.

https://doi.org/10.1182/blood.V118.21.2425.2425

Published: 2011

Journal Articles

Involvement of Death-Associated Protein Kinases In DNA Damage Responses of B-ALL Cells.

Magali Humbert, PhD,, Michaela Medova, PhD,, Barbara Geering, PhD, Wieslawa Blank-Liss, Hans-Uwe Simon, MD, PhD, Martin F. Fey, MD, Yitzhak Zimmer, PhD, Mario P. Tschan, PhD

Blood (2010) 116 (21): 3369.

https://doi.org/10.1182/blood.V116.21.3369.3369

Published: 2010

Journal Articles

The Autophagy Gene ULK1 Plays a Role In AML Differentiation and Is Negatively Regulated by the Oncogenic MicroRNA 106a

Mario P. Tschan, PhD, Melanie Jost, MD, Jasmin Batliner, PhD, Student, Martin F. Fey, MD

Blood (2010) 116 (21): 503.

https://doi.org/10.1182/blood.V116.21.503.503

Published: 2010

Journal Articles

Activation of Myeloid Differentiation-Associated Autophagy In Combination with ATRA-Therapy Enhances Neutrophil Differentiation of AML Cells.

Magali Humbert, PhD, Student, Adiran Britschgi, PhD, Hans-Uwe Simon, MD, PhD, Andreas H. Tobler, MD, Shida Yousefi, PhD, Martin F. Fey, MD, Mario P. Tschan, PhD

Blood (2010) 116 (21): 1046.

https://doi.org/10.1182/blood.V116.21.1046.1046

Published: 2010

Journal Articles

Blocking the Autophagy Gene 5 (ATG5) Impairs ATRA-Induced Myeloid Differentiation, and ATG5 Is Downregulated in AML

Adrian Britschgi, MSc, Shida Yousefi, PhD, Judith Laedrach, Deborah Shan, Hans-Uwe Simon, MD, PhD, Andreas Tobler, MD, Martin F. Fey, MD, Mario P. Tschan, PhD

Blood (2008) 112 (11): 309.

https://doi.org/10.1182/blood.V112.11.309.309

Published: 2008

Journal Articles

The Anti-Apoptotic Gene BCL2A1 Is Transcriptionally Regulated by PU.1

Mathias Jenal, MSc, Venkateshwar A. Reddy, PhD, Judith Laedrach, Deborah Shan, Andreas Tobler, MD, Bruce E. Torbett, PhD, Martin F. Fey, MD, Mario P. Tschan, PhD

Blood (2008) 112 (11): 3579.

https://doi.org/10.1182/blood.V112.11.3579.3579

Published: 2008

Journal Articles

Mir-29c and Mir-424 Are Novel Myeloid Differentiation-Associated MicroRNAs in Acute Promyelocytic Leukemia.

Jasmin Batliner, MSc, Mathias Jenal, MSc, Martin F. Fey, MD, Mario P. Tschan, PhD

Blood (2008) 112 (11): 3346.

https://doi.org/10.1182/blood.V112.11.3346.3346

Published: 2008

Journal Articles

Green Tea Catechin Epigallocatechin-3-Gallate (EGCG) Induces Cell Death in Acute Myeloid Leukemic Cells Via DAPK2 and Potentiates ATRA-Induced Neutrophil Differentiation

Adrian Britschgi, MSc, Hans-Uwe Simon, MD, PhD, Andreas Tobler, MD, Martin F. Fey, MD, Mario P. Tschan, PhD

Blood (2008) 112 (11): 2628.

https://doi.org/10.1182/blood.V112.11.2628.2628

Published: 2008

Journal Articles

NDRG1 Expression Is Inhibited in AML and Its Knockdown Attenuates Neutrophil Differentiation.

Mario P. Tschan, PhD, Deborah Shan, Judith Laedrach, Marianne Eyholzer, Elisabeth Oppliger Leibundgut, PhD, Gabriela Baerlocher, MD, Andreas Tobler, MD, Deborah Stroka, PhD, Martin F. Fey, MD

Blood (2008) 112 (11): 927.

https://doi.org/10.1182/blood.V112.11.927.927

Published: 2008

NARROW

Non-Glycolytic Role of the Myeloid Hexokinase 3 (HK3) in Therapy Responses of Myeloid Malignancies

ULK1 Blockade Preferentially Targets Germinal Centre B-Cell - Diffuse Large B-Cell Lymphoma Subtype By Attenuating Autophagy, c-MYC and Inflammation

The Transcription Factor PU.1 Controls Alternative Splicing of Cflip By Binding to SRSF2/10 Splice Factors in AML Therapy Responses

Characterization of Bypassing Kinases Inferred By Phosphoproteomics in a Midostaurin Resistant Myeloid Cell Line Model

Elucidating the Non-Catalytic Function of Fatty Acid Synthase and Its Autophagy-Dependent Degradation in Acute Myelocytic Leukemia Differentiation Therapy

Hexokinase Proteins Impart Distinct Functions in Myeloid Development and Cell Death

A Novel PU.1 - Caspase 8/cFLIP Axis in Neutrophil and Macrophage Differentiation of AML Cells

Dissecting the Autophagy Tumor Suppressor Pathway Network in Acute Promyelocytic Leukemia Therapy

Non-Canonical Autophagy during APL Therapy

PU.1 is linking the glycolytic enzyme HK3 in neutrophil differentiation and survival of APL cells

Inhibition of Key Autophagy Genes in Primary AML Patients and Their Functional Role in Neutrophil Differentiation of APL Cells

Linking the Glycolytic Enzyme HK3 to Neutrophil Differentiation of APL Cells Via PU.1

Involvement of Death-Associated Protein Kinases In DNA Damage Responses of B-ALL Cells.

The Autophagy Gene ULK1 Plays a Role In AML Differentiation and Is Negatively Regulated by the Oncogenic MicroRNA 106a

Activation of Myeloid Differentiation-Associated Autophagy In Combination with ATRA-Therapy Enhances Neutrophil Differentiation of AML Cells.

Blocking the Autophagy Gene 5 (ATG5) Impairs ATRA-Induced Myeloid Differentiation, and ATG5 Is Downregulated in AML

The Anti-Apoptotic Gene BCL2A1 Is Transcriptionally Regulated by PU.1

Mir-29c and Mir-424 Are Novel Myeloid Differentiation-Associated MicroRNAs in Acute Promyelocytic Leukemia.

Green Tea Catechin Epigallocatechin-3-Gallate (EGCG) Induces Cell Death in Acute Myeloid Leukemic Cells Via DAPK2 and Potentiates ATRA-Induced Neutrophil Differentiation

NDRG1 Expression Is Inhibited in AML and Its Knockdown Attenuates Neutrophil Differentiation.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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