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Journal Articles

Accumulation of Endogenous DNA Damage Sustain Malignant Progression and Increase Therapy Resistance in Multiple Myeloma

Maria Gkotzamanidou, MD PhD, Evangelos Terpos, MD PhD, Nikhil C. Munshi, MD, Vassilis L. Souliotis, PhD, Meletios A. Dimopoulos, MD

Blood (2019) 134 (Supplement_1): 1788.

https://doi.org/10.1182/blood-2019-123502

Published: 2019

Journal Articles

Ongoing Spontaneous DNA Damage Creates Synthetic Lethality Targeted By Novel RAD51 Inhibitors in Multiple Myeloma

Subodh Kumar, PhD, Maria Gkotzamanidou, MD PhD, Srikanth Talluri, PhD, Melinda Day, PhD, Mychell Neptune, Lakshmi B. Potluri, Chandraditya Chakraborty, PhD, Kevin Mills, PhD, Masood A. Shammas, PhD, Nikhil C. Munshi, MD

Blood (2019) 134 (Supplement_1): 4378.

https://doi.org/10.1182/blood-2019-129121

Published: 2019

Journal Articles

HDAC8 Maintain Cytoskeleton Integrity Via Homologous Recombination and Represent a Novel Therapeutic Target in Multiple Myeloma

Zuzana Chyra, PhD, Maria Gkotzamanidou, MD PhD, Masood A. Shammas, PhD, Vassilis L. Souliotis, PhD, Yan Xu, MD, Mehmet K. Samur, PhD, Aaron B. Beeler, PhD, Roman Hajek, MD, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD

Blood (2019) 134 (Supplement_1): 4385.

https://doi.org/10.1182/blood-2019-130700

Published: 2019

Journal Articles

Panobinostat Potentiates Melphalan-Induced Apoptosis of Myeloma Cells and Minimizes Untoward Side Effects in Multiple Myeloma

Maria Gkotzamanidou, MD PhD, Vassilis L. Souliotis, PhD, Meletios A. Dimopoulos, MD, Evangelos Terpos, MD PhD

Blood (2019) 134 (Supplement_1): 2528.

https://doi.org/10.1182/blood-2019-123338

Published: 2019

Journal Articles

Dysregulation of SHFM1, a Novel Target for Prevention of Genomic Instability in Myeloma, Is Associated with Epigenetic Changes at Specific CpG Sites

Masood Shammas, PhD, Subodh Kumar, PhD, Jagannath Pal, PhD, Puru Nanjappa, MS, Mehmat Samur, PhD, Maria Gkotzamanidou, MD PhD, Jialan Shi, MD PhD, Nikhil C. Munshi, MD

Blood (2014) 124 (21): 862.

https://doi.org/10.1182/blood.V124.21.862.862

Published: 2014

Journal Articles

Bone Marrow Microenvironment Regulates Alternative Splicing Events in Myeloma Cells through Downregulation of RNA Binding Protein Fox2

Blood (2014) 124 (21): 4714.

https://doi.org/10.1182/blood.V124.21.4714.4714

Published: 2014

Journal Articles

HDAC8 Mediates Homologous Recombination and Cytoskeleton Integrity in Myeloma with Potential Impact on Cell Growth and Survival

Maria Gkotzamanidou, MD PhD, Masood Shammas, PhD, Jesus Martin Sanchez, MD, Lai Ding, Stephane Minvielle, Florence Magrangeas, Herve Avet-Loiseau, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2014) 124 (21): 416.

https://doi.org/10.1182/blood.V124.21.416.416

Published: 2014

Journal Articles

Telomerase-Mediated Repair of Induced DNA Breaks Leads to Increased Genomic Instability in Multiple Myeloma Cells: Possible Mechanism and Translational Significance

Jagannath Pal, PhD, Masood Shammas, PhD, Subodh Kumar, PhD, Maria Gkotzamanidou, MD PhD, Puru Nanjappa, MS, Leutz Buon, Nikhil C. Munshi, MD

Blood (2014) 124 (21): 5170.

https://doi.org/10.1182/blood.V124.21.5170.5170

Published: 2014

Journal Articles

Ongoing Spontaneous DNA Damage and the Role of Aberrant Epigenome in Multiple Myeloma

Maria Gkotzamanidou, MD PhD, Masood Shammas, PhD, Vassilis L. Souliotis, Weihua Song, MD, Jagannath Pal, MBBS, PhD, Puru Nanjappa, MS, Naim Rashid, PhD, Kenneth C. Anderson, MD, Meletios A. Dimopoulos, MD, James Bradner, MD, Nikhil C. Munshi, MD

Blood (2014) 124 (21): 3398.

https://doi.org/10.1182/blood.V124.21.3398.3398

Published: 2014

Journal Articles

LSD1 Impairs the Epithelial-Mesenchymal Transition (EMT) and Osteoclastogenesis Potency in Multiple Myeloma and Synergistically Induces Cytotoxicity with HDAC Inhibitors

Maria Gkotzamanidou, MD PhD, Mariateresa Fulciniti, PhD, Jesús Martín Sanchez, Mehmet Kemal Samur, PhD, Giovanni Parmigiani, PhD, Kenneth C. Anderson, Nikhil C. Munshi, MD

Blood (2014) 124 (21): 3410.

https://doi.org/10.1182/blood.V124.21.3410.3410

Published: 2014

Journal Articles

Elevated APE1 Mediates Dysregulation of Homologous Recombination in Myeloma: Mechanisms and Translational Significance

Subodh Kumar, PhD, Maria Gkotzamanidou, MD PhD, Jagannath Pal, PhD, Renquan Lu, MD PhD, Puru Nanjappa, MS, Jialan Shi, MD PhD, Masood Shammas, PhD, Nikhil C. Munshi, MD

Blood (2014) 124 (21): 2074.

https://doi.org/10.1182/blood.V124.21.2074.2074

Published: 2014

Journal Articles

Spontaneous DNA Damage and Aberrant Epigenome In Multiple Myeloma Constitute The Path To Disease Genomic Instability

Maria Gkotzamanidou, MD, PhD, Masood A. Shammas, Vassilis L. Souliotis, Jagannath Pal, MD, Jun Qi, Ph.D., Andrew Brown, James E Bradner, MD, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD

Blood (2013) 122 (21): 4884.

https://doi.org/10.1182/blood.V122.21.4884.4884

Published: 2013

Journal Articles

Role Of Base Excision Repair Associated AP Nuclease Activity In The Induction Of Homologous Recombination Repair Pathway and Survival Of MM Cells Following DNA Damage

Subodh Kumar, PhD, Jagannath Pal, PhD, Jialan Shi, PhD, Puru Nanjappa, MS, Maria Gkotzamanidou, MD, Masood Shammas, PhD, Nikhil Munshi, MD

Blood (2013) 122 (21): 1248.

https://doi.org/10.1182/blood.V122.21.1248.1248

Published: 2013

Journal Articles

Inhibition Of H3K27-Methylome As a Novel Therapeutic Strategy In Multiple Myeloma

Maria Gkotzamanidou, MD, PhD, Masood A Shammas, PhD, Jun Qi, PhD, Mehmet Kemal Samur, PhD, Teru Hideshima, MD, PhD, Meletios A. Dimopoulos, MD, Kenneth C. Anderson, MD, James E Bradner, MD, Nikhil Munshi, MD

Blood (2013) 122 (21): 3162.

https://doi.org/10.1182/blood.V122.21.3162.3162

Published: 2013

Journal Articles

Telomerase Contributes To Repair Of DNA Breaks In Myeloma Cells By Incorporating “TTAGGG” Sequences Within Genome: Biological and Translational Significance

Jagannath Pal, PhD, Jie Ding, PhD, Subodh Kumar, PhD, Zachary Hunter, Teresa Calimeri, MD, Jianhong Lin, Maria Gkotzamanidou, MD, Giovanni Parmigiani, PhD, Steven Treon, Masood Shammas, PhD, Nikhil Munshi, MD

Blood (2013) 122 (21): 1249.

https://doi.org/10.1182/blood.V122.21.1249.1249

Published: 2013

Journal Articles

Bone Marrow Microenvironment Affects The Pathogenesis Of Multiple Myeloma Through Downregulation Of Alternative Splicing Factor Fox2 In Myeloma Cells

Weihua Song, MD, Chaolin Zhang, PhD, Yiguo Hu, PhD, Maria Gkotzamanidou, MD, Parantu Shah, PhD, Weisong Shan, MD PhD, Guang Yang, PhD, Samir B. Amin, MBBS, Yu-Tzu Tai, PhD, Yi Li, PhD, Adam Sperling, MD, PhD, Naim Rashid, PhD, Florence Magrangeas, PhD, Stephane Minvielle, PhD, Hervé Avet-Loiseau, MD, PhD, Kenneth C. Anderson, MD, Cheng Li, PhD, Nikhil C. Munshi, MD

Blood (2013) 122 (21): 3085.

https://doi.org/10.1182/blood.V122.21.3085.3085

Published: 2013

NARROW

Accumulation of Endogenous DNA Damage Sustain Malignant Progression and Increase Therapy Resistance in Multiple Myeloma

Ongoing Spontaneous DNA Damage Creates Synthetic Lethality Targeted By Novel RAD51 Inhibitors in Multiple Myeloma

HDAC8 Maintain Cytoskeleton Integrity Via Homologous Recombination and Represent a Novel Therapeutic Target in Multiple Myeloma

Panobinostat Potentiates Melphalan-Induced Apoptosis of Myeloma Cells and Minimizes Untoward Side Effects in Multiple Myeloma

Dysregulation of SHFM1, a Novel Target for Prevention of Genomic Instability in Myeloma, Is Associated with Epigenetic Changes at Specific CpG Sites

Bone Marrow Microenvironment Regulates Alternative Splicing Events in Myeloma Cells through Downregulation of RNA Binding Protein Fox2

HDAC8 Mediates Homologous Recombination and Cytoskeleton Integrity in Myeloma with Potential Impact on Cell Growth and Survival

Telomerase-Mediated Repair of Induced DNA Breaks Leads to Increased Genomic Instability in Multiple Myeloma Cells: Possible Mechanism and Translational Significance

Ongoing Spontaneous DNA Damage and the Role of Aberrant Epigenome in Multiple Myeloma

LSD1 Impairs the Epithelial-Mesenchymal Transition (EMT) and Osteoclastogenesis Potency in Multiple Myeloma and Synergistically Induces Cytotoxicity with HDAC Inhibitors

Elevated APE1 Mediates Dysregulation of Homologous Recombination in Myeloma: Mechanisms and Translational Significance

Spontaneous DNA Damage and Aberrant Epigenome In Multiple Myeloma Constitute The Path To Disease Genomic Instability

Role Of Base Excision Repair Associated AP Nuclease Activity In The Induction Of Homologous Recombination Repair Pathway and Survival Of MM Cells Following DNA Damage

Inhibition Of H3K27-Methylome As a Novel Therapeutic Strategy In Multiple Myeloma

Telomerase Contributes To Repair Of DNA Breaks In Myeloma Cells By Incorporating “TTAGGG” Sequences Within Genome: Biological and Translational Significance

Bone Marrow Microenvironment Affects The Pathogenesis Of Multiple Myeloma Through Downregulation Of Alternative Splicing Factor Fox2 In Myeloma Cells

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American Society of Hematology

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ASH Publications

American Society of Hematology

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