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Journal Articles

Single Agent and Combinatorial Efficacy of First-in-Class Small Molecule ONC201 in Acute Leukemia and Multiple Myeloma

Varun V Prabhu, PhD, Amriti Lulla, Christina L Kline, PhD, Peter J Van den Heuvel, PhD, Mala K. Talekar, MD, Jessica M Wagner, Rohinton S Tarapore, PhD, David T Dicker, Mathew J Garnett, PhD, Ultan McDermott, MD PhD, Cyril H Benes, PhD, Jeffrey J. Pu, MD PhD, David F. Claxton, MD, Wolfgang Oster, MD PhD, Joshua E Allen, PhD, Wafik S. El-Deiry, MD PhD

Blood (2016) 128 (22): 2759.

https://doi.org/10.1182/blood.V128.22.2759.2759

Published: 2016

Journal Articles

Potent Anti-Leukemic Effects of Small Molecule ONC212, a Member of the Imipridone Class of Anti-Cancer Compounds

Varun V Prabhu, PhD, Rohinton S Tarapore, PhD, Mathew J Garnett, PhD, Ultan McDermott, MD PhD, Cyril H Benes, PhD, Jessica M Wagner, Wafik S. El-Deiry, MD PhD, Martin Stogniew, PhD, Wolfgang Oster, MD PhD, Joshua E Allen, PhD

Blood (2016) 128 (22): 5133.

https://doi.org/10.1182/blood.V128.22.5133.5133

Published: 2016

Journal Articles

Caspase-Dependent Anti-Tumor Effects of ONC201/TIC10 on Acute Myeloid Leukemia (AML) and Multiple Myeloma (MM)

Amriti R. Lulla, Christina Leah B Kline, PhD, Liz J. Hernandez-Borrero, Varun Vijay Prabhu, Jessica M Wagner, David T. Dicker, Nathan G. Dolloff, PhD, Brian M Barth, PhD, Jeffrey J Pu, MD PhD, David F. Claxton, MD, Joshua E. Allen, PhD, Wafik S. El-Deiry, MD PhD FACP

Blood (2014) 124 (21): 5224.

https://doi.org/10.1182/blood.V124.21.5224.5224

Published: 2014

Journal Articles

Screen of Small Molecule ONC201/TIC10 Identifies Single Agent Activity and Combinatorial Efficacy with Bortezomib, Rituximab or Dexamethasone in Killing of Acute Lymphoblastic Leukemia Cells

Jessica M Wagner, Varun Vijay Prabhu, Leah L. Kline, PhD, Amriti R. Lulla, Liz J. Hernandez-Borrero, Jeffrey J. Pu, MD PhD, David T. Dicker, Brian M Barth, PhD, David F. Claxton, MD, Joshua E. Allen, PhD, Wafik S. El-Deiry, MD PhD FACP

Blood (2014) 124 (21): 5233.

https://doi.org/10.1182/blood.V124.21.5233.5233

Published: 2014

Journal Articles

Small Molecule ONC201/TIC10 Induces Caspase-Dependent Apoptosis in Acute Lymphoblastic Leukemia Cells Via Modulation of Bcl-2 and IAP Family Proteins

Varun Vijay Prabhu, Amriti R. Lulla, Jessica M Wagner, Liz J. Hernandez-Borrero, Mala K. Talekar, MD, Christina L. Kline, PhD, David T. Dicker, Brian M Barth, PhD, Jeffrey J. Pu, MD PhD, David F. Claxton, MD, Joshua E. Allen, PhD, Wafik S. El-Deiry, MD PhD FACP

Blood (2014) 124 (21): 5237.

https://doi.org/10.1182/blood.V124.21.5237.5237

Published: 2014

Journal Articles

Functionally Altered GPI-Anchor Negative Treg Following Alemtuzumab-Based T-Cell Depletion Are Associated with Acute Gvhd.

Eva M Wagner, Lukas A Schaefer, Tobias Bopp, Matthias Theobald, MD, PhD, Wolfgang Herr, MD, Ralf G Meyer

Blood (2012) 120 (21): 3059.

https://doi.org/10.1182/blood.V120.21.3059.3059

Published: 2012

Journal Articles

Impact of Prophylactic CD8-Depleted Donor-Lymphocyte Infusions After Allogeneic Hematopoietic Stem Cell Transplantation and Alemtuzumab Mediated T-Cell Depletion,

Eva M Wagner, MD, Daniela Wehler, MD, Karin Kolbe, MD, Matthias Theobald, MD, PhD, Wolfgang Herr, MD, Ralf G Meyer, MD

Blood (2011) 118 (21): 4109.

https://doi.org/10.1182/blood.V118.21.4109.4109

Published: 2011

Journal Articles

Long-Term Persistence of Functionally Altered GPI-Anchor Negative T-Cell Subsets After Alemtuzumab-Based T-Cell Depleted Hematopoietic Stem Cell Transplantation.

Eva M Wagner, Aline N Lay, Timo Schmitt, Julia Hemmerling, Diana Wolff, Christoph Huber, Wolfgang Herr, Ralf G Meyer

Blood (2009) 114 (22): 2438.

https://doi.org/10.1182/blood.V114.22.2438.2438

Published: 2009

Journal Articles

The CD38-Positive and CD38-Negative Subsets of CD34(high)-Positive Primary Acute Myeloid Leukemia Blasts Differ Considerably in the Expression of Immune Recognition Molecules

Eva Distler, Anna Jürchott, Abdo Konur, Astrid Schneider, Eva M. Wagner, Christoph Huber, Ralf G. Meyer, Wolfgang Herr

Blood (2008) 112 (11): 2936.

https://doi.org/10.1182/blood.V112.11.2936.2936

Published: 2008

Journal Articles

Reconstitution of CD52-Negative CD4 T Cells after Alemtuzumab-Based T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

Eva M Wagner, MD, Aline N Lay, Sina Wenzel, Timo Schmitt, Julia Hemmerling, Abdo Konur, PhD, Klaus Bender, PhD, Christoph Huber, MD, Wolfgang Herr, MD, Ralf G Meyer, MD

Blood (2008) 112 (11): 1182.

https://doi.org/10.1182/blood.V112.11.1182.1182

Published: 2008

Journal Articles

CD8-Depleted Donor Lymphocyte Infusions Convert Mixed into Complete Donor T-Cell Chimerism after T-Cell Depleted Allogeneic Stem Cell Transplantation.

Ralf G Meyer, MD, Eva M Wagner, MD, Timo Schmitt, Klaus Bender, PhD, Udo F Hartwig, PhD, Christoph Huber, MD, Karin Kolbe, MD, Wolfgang Herr, MD

Blood (2008) 112 (11): 2160.

https://doi.org/10.1182/blood.V112.11.2160.2160

Published: 2008

Journal Articles

The endogenous danger signal, crystalline uric acid, signals for enhanced antibody immunity

Marshall D. Behrens, Wolfgang M. Wagner, Christopher J. Krco, Courtney L. Erskine, Kimberly R. Kalli, James Krempski, Ekram A. Gad, Mary L. Disis, Keith L. Knutson

Blood (2008) 111 (3): 1472–1479.

https://doi.org/10.1182/blood-2007-10-117184

Published: 2008

Journal Articles

Vaccination with WT1 and PR3 Derived Peptides in Patients with AML/MDS and MUC1 Peptides in Patients with Multiple Myeloma - Preliminary Results.

Eva M. Wagner, Juergen Kuball, MD, Mohamed Wattad, MD, Christoph Huber, MD, Wolfgang Heit, MD, Matthias Theobald, MD

Blood (2006) 108 (11): 4582.

https://doi.org/10.1182/blood.V108.11.4582.4582

Published: 2006

Journal Articles

Tobacco, cocoa, coffee, and ragweed: cross-reacting allergens that activate factor-XII-dependent pathways

CG Becker, N Van Hamont, M Wagner

Blood (1981) 58 (5): 861–867.

https://doi.org/10.1182/blood.V58.5.861.861

Published: 1981

NARROW

Single Agent and Combinatorial Efficacy of First-in-Class Small Molecule ONC201 in Acute Leukemia and Multiple Myeloma

Potent Anti-Leukemic Effects of Small Molecule ONC212, a Member of the Imipridone Class of Anti-Cancer Compounds

Caspase-Dependent Anti-Tumor Effects of ONC201/TIC10 on Acute Myeloid Leukemia (AML) and Multiple Myeloma (MM)

Screen of Small Molecule ONC201/TIC10 Identifies Single Agent Activity and Combinatorial Efficacy with Bortezomib, Rituximab or Dexamethasone in Killing of Acute Lymphoblastic Leukemia Cells

Small Molecule ONC201/TIC10 Induces Caspase-Dependent Apoptosis in Acute Lymphoblastic Leukemia Cells Via Modulation of Bcl-2 and IAP Family Proteins

Functionally Altered GPI-Anchor Negative Treg Following Alemtuzumab-Based T-Cell Depletion Are Associated with Acute Gvhd.

Impact of Prophylactic CD8-Depleted Donor-Lymphocyte Infusions After Allogeneic Hematopoietic Stem Cell Transplantation and Alemtuzumab Mediated T-Cell Depletion,

Long-Term Persistence of Functionally Altered GPI-Anchor Negative T-Cell Subsets After Alemtuzumab-Based T-Cell Depleted Hematopoietic Stem Cell Transplantation.

The CD38-Positive and CD38-Negative Subsets of CD34(high)-Positive Primary Acute Myeloid Leukemia Blasts Differ Considerably in the Expression of Immune Recognition Molecules

Reconstitution of CD52-Negative CD4 T Cells after Alemtuzumab-Based T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

CD8-Depleted Donor Lymphocyte Infusions Convert Mixed into Complete Donor T-Cell Chimerism after T-Cell Depleted Allogeneic Stem Cell Transplantation.

The endogenous danger signal, crystalline uric acid, signals for enhanced antibody immunity

Vaccination with WT1 and PR3 Derived Peptides in Patients with AML/MDS and MUC1 Peptides in Patients with Multiple Myeloma - Preliminary Results.

Tobacco, cocoa, coffee, and ragweed: cross-reacting allergens that activate factor-XII-dependent pathways

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American Society of Hematology

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American Society of Hematology

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