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Lukas T Jeker
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Journal Articles

Base Edited HSPCs Are Shielded from Targeted CD33 Therapy but Preserve CD33 Expression

Astrid Beerlage, Simon Garaudé, Rosalba Lepore, Thomas Burgold, Anna Camus, Mathilde Testut, Stefanie Urlinger, Lukas T Jeker
Journal: Blood
Blood (2023) 142 (Supplement 1): 3422.
https://doi.org/10.1182/blood-2023-177706
Published: 2023
Journal Articles

Hematopoietic Stem Cells Expressing Engineered CD45 Enable a Near Universal Targeted Therapy for Hematologic Diseases

Romina Marone, Simon Garaudé, Rosalba Lepore, Anna Devaux, Astrid Beerlage, Federico Simonetta, Anna Camus, Izabela Durzynska, Ian Kirby, Patrick Van Berkel, Christian Kunz, Stefanie Urlinger, Lukas T Jeker
Journal: Blood
Blood (2023) 142 (Supplement 1): 3418.
https://doi.org/10.1182/blood-2023-173706
Published: 2023
Journal Articles

Function-Preserving Single Amino Acid Substitutions Shield Hematopoietic Stem and Progenitor Cells from CD117 Targeted Immunotherapy In Vivo

Romina Marone, Rosalba Lepore, Julia Rositzka, Viviane Dettmer-Monaco, Alessandro dell' Aglio, Giuseppina Capoferri, Julie Brault, Emiel Ten Buren, Thomas Burgold, Anna Camus, Christopher Divsalar, Laura Garcia Prat, Anna Haydn, Felix Hermann, Marcel Heugel, Andreja Knezevic, Frank Michael Lehmann, Valentin Do Sacramento, Alessandro Sinopoli, Lisa C Wellinger, Amélie Wiederkehr, Saniye Yumlu, Toni Cathomen, Thomas Winkler, Tatjana I Cornu, Stefanie Urlinger, Lukas T Jeker
Journal: Blood
Blood (2022) 140 (Supplement 1): 4493–4494.
https://doi.org/10.1182/blood-2022-165274
Published: 2022
Journal Articles

Engineered Single Amino Acid Substitutions Protect Hematopoietic Stem and Progenitor Cells from CD123 Targeted Immunotherapy

Emmanuelle Landmann, Anna Devaux, Rosalba Lepore, Romina Marone, Corinne Engdahl, Marko Hasiuk, Giuseppina Capoferri, Amélie Wiederkehr, Lisa C Wellinger, Alessandro Sinopoli, Valentin Do Sacramento, Anna Haydn, Laura Garcia Prat, Christopher Divsalar, Anna Camus, Julie Brault, Liwen Xu, Torsten Schwede, Matthew H. Porteus, Stefanie Urlinger, Lukas T Jeker
Journal: Blood
Blood (2022) 140 (Supplement 1): 5724–5725.
https://doi.org/10.1182/blood-2022-163815
Published: 2022
Journal Articles

Maintenance of a normal thymic microenvironment and T-cell homeostasis require Smad4-mediated signaling in thymic epithelial cells

Lukas T. Jeker, Thomas Barthlott, Marcel P. Keller, Saulius Zuklys, Mathias Hauri-Hohl, Chu-Xia Deng, Georg A. Holländer
Journal: Blood
Blood (2008) 112 (9): 3688–3695.
https://doi.org/10.1182/blood-2008-04-150532
Published: 2008
Includes: Supplemental data
Journal Articles

TGF-β signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution

Mathias M. Hauri-Hohl, Saulius Zuklys, Marcel P. Keller, Lukas T. Jeker, Thomas Barthlott, Anne M. Moon, Jürgen Roes, Georg A. Holländer
Journal: Blood
Blood (2008) 112 (3): 626–634.
https://doi.org/10.1182/blood-2007-10-115618
Published: 2008
Includes: Supplemental data
Journal Articles

Keratinocyte growth factor (KGF) enhances postnatal T-cell development via enhancements in proliferation and function of thymic epithelial cells

Simona W. Rossi, Lukas T. Jeker, Tomoo Ueno, Sachiyo Kuse, Marcel P. Keller, Saulius Zuklys, Andrei V. Gudkov, Yousuke Takahama, Werner Krenger, Bruce R. Blazar, Georg A. Holländer
Journal: Blood
Blood (2007) 109 (9): 3803–3811.
https://doi.org/10.1182/blood-2006-10-049767
Published: 2007