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Journal Articles

Automated Manufacture of CAR19 Donor Lymphocytes Incorporated into an Escalated Dose DLI Protocol: Preliminary Results from the CARD Study

Claire Roddie, PhD MD, Lauren Nickolay, PhD, Ulrike Mock, PhD, Praveen Aujla, Gordon W Cheung, Lucas Chan, Alex Day, Graham Wheeler, Bilyana Popova, Kim Champion, Yashma Pathak, Nasir Mahmoud, Helen Lowe, Gulrukh Ahsan, Nourredine Himoudi, Farzin Farzaneh, PhD, David C. Linch, FRCP, Adrian J Thrasher, MD PhD FMedSci, Martin Pule, PhD, Waseem Qasim, MD PhD, Karl Peggs, MBBChir, MRCP, FRCPath
Journal: Blood
Blood (2017) 130 (Supplement 1): 1993.
https://doi.org/10.1182/blood.V130.Suppl_1.1993.1993
Published: 2017
Journal Articles

A Novel Second Generation CD19 CAR for Therapy of High Risk/Relapsed Paediatric CD19 + Acute Lymphoblastic Leukaemia and Other Haematological Malignancies: Preliminary Results from the Carpall Study

Sara Ghorashian, MD PhD FRCPath, Anne Marijn Kramer, MD, Sarah Jayne Albon, BSc, MSc, Catherine Irving, BSc, Lucas Chan, PhD, Fernanda Castro, PhD, Bilyana Popova, Kim Champion, PhD, Gary Wright, Hong Zhan, PhD, Waseem Qasim, MBBS PhD, Robert Wynn, Rachael Hough, MD BMBS, FRCP, FRCPath, Farzin Farzaneh, Martin A Pule, MD PhD, Persis J Amrolia, Professor
Journal: Blood
Blood (2016) 128 (22): 4026.
https://doi.org/10.1182/blood.V128.22.4026.4026
Published: 2016
Journal Articles

CD80-IL2 Expressing Myeloma Cells for Immune Gene Therapy of Multiple Myeloma

Giulia Giunti, David Malone, Lucas Chan, Darling David, Shahram Y Kordasti, MD, PhD, Linda Barber, Oppenheim David, Farzin Farzaneh, DPhil, Stephen Schey
Journal: Blood
Blood (2011) 118 (21): 4718.
https://doi.org/10.1182/blood.V118.21.4718.4718
Published: 2011
Journal Articles

RFUSIN2 - a Clinical Grade Lentiviral Vector Co-Expressing CD80/IL-2 Manufactured Under GMP for a Phase I Clinical Trial Study of Immune Gene Therapy for Poor Prognosis Acute Myeloid Leukaemia

Lucas Chan, Wendy Ingram, Nicola Hardwick, David Darling, Joti Bhalla, Aytug Kizilors, Shahram Y Kordasti, Ghulam J Mufti, Farzin Farzaneh
Journal: Blood
Blood (2008) 112 (11): 4630.
https://doi.org/10.1182/blood.V112.11.4630.4630
Published: 2008
Journal Articles

In-Vitro Culture of Human CD80/IL2 Lentivirus Transduced Acute Myeloid Leukemia Cells (AML) Promote NK Cell Activation and Cytolytic Activity

Wendy Ingram, Lucas Chan, Hayrettin Guven, Shahram Kordasti, Linda Barber, Nicola Hardwick, David Darling, Ghulam J Mufti, Farzin Farzaneh
Journal: Blood
Blood (2008) 112 (11): 2969.
https://doi.org/10.1182/blood.V112.11.2969.2969
Published: 2008
Journal Articles

IL-2/B7.1 Fusagene Transduction of AML Blasts by a Self-Inactivating Lentiviral Vector Stimulates T Cell Responses in Vitro: A Strategy To Generate Whole Cell Vaccines for AML.

Lucas Chan, PhD, Nicola Hardwick, MPhil, Dave Darling, PhD, Joanna Galea-Lauri, PhD, Joop Gäken, PhD, Stephen Devereux, MD PhD, Mike Kemeny, PhD FRCPath, Ghulam Mufti, MD PhD DSc FRCP, Farzin Farzaneh, DPhil FRCPath
Journal: Blood
Blood (2004) 104 (11): 5275.
https://doi.org/10.1182/blood.V104.11.5275.5275
Published: 2004