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Lilian Varricchio, PhD
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Journal Articles

Rationale for and Results of a Phase I Study of the TGF-β 1/3 Inhibitor AVID200 in Subjects with Myelofibrosis: MPN-RC 118 Trial

John Mascarenhas, MD, Heidi E. Kosiorek, MS, Lilian Varricchio, PhD, Rupali Bhave, MD, Andrew T. Kuykendall, MD, Rami Komrokji, MD, Aaron T. Gerds, MDMS, Jeanne M. Palmer, MD, Amelia R. Gabler, Lonette Sandy, Anna Rita Migliaccio, PhD, Mohamed E Salama, MD, Rona Singer Weinberg, PhD, Maureen O'Connor-McCourt, PhD, Gilles Tremblay, PhD, Paul I. Nadler, MD, Amylou C. Dueck, PhD, Ruben A. Mesa, MD FACP, Ronald Hoffman, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 6–8.
https://doi.org/10.1182/blood-2020-140830
Published: 2020
Journal Articles

AVID200, a Potent Trap for TGF-β Ligands Inhibits TGF-β1 Signaling in Human Myelofibrosis

Lilian Varricchio, PhD, John Mascarenhas, MD, Anna Rita Migliaccio, PhD, Maureen O'Connor-McCourt, PhD, Gilles Tremblay, Jean-François Denis, Camelia Iancu-Rubin, PhD, Ronald Hoffman, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1791.
https://doi.org/10.1182/blood-2018-99-116474
Published: 2018
Journal Articles

The Carboxy-Terminal Domain of Calreticulin (CALR) Exports the Glucocorticoid Receptor (GR) from the Nucleus to the Cytoplasm of Human Erythroid Cells Resetting Their Stress Response

Anna Rita Migliaccio, PhD, Mario Falchi, PhD, Lilian Varricchio, PhD, Fabrizio Martelli, PhD, Francesca Masiello, MS, Manuela Marra, PhD, Orietta Picconi, Agostino Tafuri, MD, Gabriella Girelli, MD, Carolyn F. Whitsett, MD
Journal: Blood
Blood (2016) 128 (22): 545.
https://doi.org/10.1182/blood.V128.22.545.545
Published: 2016
Journal Articles

Ribosomal Deficiency Due to Activation of the Thrombopoietin Axis May be Involved in the Reduced Levels of GATA1 Expressed By Megakaryocytes (MKs) from the Gata1 low Model of Myelofibrosis

Anna Rita F Migliaccio, PhD, Maria Zingariello, MD, Laura Sancillo, MS, Fabrizio Martelli, PhD, Fiorella Ciaffoni, PhD, Francesca Masiello, MS, Ilaria Ceglia, PhD, Lilian Varricchio, PhD, Rosa Alba Rana, MD, Changsheng Zhao, PhD, John Crispino, PhD
Journal: Blood
Blood (2016) 128 (22): 4275.
https://doi.org/10.1182/blood.V128.22.4275.4275
Published: 2016
Journal Articles

Phosphoproteomic Landscaping Unveils Constitutive cKIT Activation in Human Erythroblasts from Polycythemia Vera (PV) Patients

Lilian Varricchio, PhD, Giulia Federici, PhD, Francesca Masiello, MS, Fabrizio Martelli, PhD, Mario Falchi, PhD, Orietta Picconi, Gabriella Girelli, MD, Agostino Tafuri, MD, Emanuel Petricoin III, PhD, Ann Zeuner, PhD, Anna Rita Migliaccio, PhD
Journal: Blood
Blood (2016) 128 (22): 399.
https://doi.org/10.1182/blood.V128.22.399.399
Published: 2016
Journal Articles

Glucocorticoid Regulation of Erythropoiesis in Humans: A Study of Patients with Cushing's Disease

Eliza B Geer, MD, Lilian Varricchio, PhD, Fabrizio Martelli, PhD, Wu He, PhD, Lizette Couto, Yelena Lazar, Vanessa Cohen, Anna Rita Migliaccio, PhD
Journal: Blood
Blood (2015) 126 (23): 2135.
https://doi.org/10.1182/blood.V126.23.2135.2135
Published: 2015
Journal Articles

The JAK2 V617F Mutation Disrupts the Regulatory Activity Exerted By Calreticulin on the Glucocorticoid Receptor in Erythroid Cells

Mario Falchi, PhD, Lilian Varricchio, PhD, Fabrizio Martelli, PhD, Francesca Masiello, Orietta Piccioni, Agostino Tafuri, MD, Gabriella Girelli, Camelia Iancu-Rubin, PhD, Ronald Hoffman, MD, Anna Rita Migliaccio, PhD
Journal: Blood
Blood (2015) 126 (23): 5216.
https://doi.org/10.1182/blood.V126.23.5216.5216
Published: 2015
Journal Articles

Different Stress Responses Mediate the Massive Erythroblast Expansion Occurring in Cultures of Human Progenitor Cells Derived From Cord Blood and Adult Blood in the Presence of Glucocorticoid Receptor Agonists.

Giulia Federici, MS, Valentina Tirelli, MS, Francesca Masiello, MS, Lilian Varricchio, PhD, Gabriella Girelli, MD, Ann Zeuner, PhD, Emanuel F. Petricoin, PhD, Anna Rita F Migliaccio, PhD
Journal: Blood
Blood (2012) 120 (21): 2339.
https://doi.org/10.1182/blood.V120.21.2339.2339
Published: 2012
Journal Articles

Identification of a New Functional HDAC Complex Composed by HDAC5, GATA1 and EKLF in Human Erythroid Cells

Lilian Varricchio, PhD, Carmela Dell'Aversana, PhD, Angela Nebbioso, MD, Giovanni Migliaccio, PhD, Lucia Altucci, MD, James J. Bieker, PhD, Anna Rita F Migliaccio, PhD
Journal: Blood
Blood (2012) 120 (21): 979.
https://doi.org/10.1182/blood.V120.21.979.979
Published: 2012