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Journal Articles

Modulating Metabolic Reprogramming By Phosphoglycerate Dehydrogenase (PHGDH) Inhibitors in Omipalisib-Refractory AML

Chi-Yang Tseng, Yu-Hsuan Fu, Ching-Ying Kuo, Hsin-An Hou, Da-Liang Ou, Liang-In Lin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1432.
https://doi.org/10.1182/blood-2023-185713
Published: 2023
Journal Articles

Transcriptomic-Based in silico Drug Screening Reveals Dual PI3K/mTOR Inhibitors Overcome Cabozantinib-Resistance of FLT3 -ITD AML Cells

Chi-Yang Tseng, Yu-Hsuan Fu, Ang-Chu Huang, Da-Liang Ou, Ching-Ying Kuo, Liang-In Lin
Journal: Blood
Blood (2022) 140 (Supplement 1): 4947–4948.
https://doi.org/10.1182/blood-2022-163124
Published: 2022
Journal Articles

Strategies for Alleviating Tyrosine Kinase Resistance in Acute Myeloid Leukemia By Modulating p53 Signaling Pathway with Small Molecules

Chi-Yang Tseng, Fang-Yu Lo, Yu-Hsuan Fu, Da-Liang Ou, Hsin-An Hou, Liang-In Lin
Journal: Blood
Blood (2022) 140 (Supplement 1): 3086–3087.
https://doi.org/10.1182/blood-2022-163072
Published: 2022
Journal Articles

Metabolic Profiling Reveals Cellular Reprogramming of Acute Myeloid Leukemia By Omipalisib through Serine Synthesis Pathway

Liang-In Lin, Tseng Chiyang, Yu-Hsuan Fu, Hsin-An Hou, Wen-Chien Chou, Hwei-Fang Tien
Journal: Blood
Blood (2021) 138 (Supplement 1): 3296.
https://doi.org/10.1182/blood-2021-149200
Published: 2021
Journal Articles

Minimal Residual Disease Monitoring By Next-Generation Sequencing in Patients with Acute Myeloid Leukemia: MRD Positivity after First Consolidation Chemotherapy Can Better Predict Clinical Outcomes Than That after Induction Chemotherapy

Cheng-Hong Tsai, MD MSc, Jih-Luh Tang, MD, PhD, Feng-Ming Tien, MD, M.Sc, Yuan-Yeh Kuo, PhD, Chien-Chin Lin, MD, Mei-Hsuan Tseng, M.Sc., Yen-Ling Peng, M.Sc., Ming-Chih Liu, Chia-Wen Liu, Ming Yao, Liang-In Lin, PhD, Wen-Chien Chou, MD, PhD, Chien-Yu Chen, PhD, Hsin-An Hou, Hwei-Fang Tien, MD, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2698.
https://doi.org/10.1182/blood-2019-126870
Published: 2019
Journal Articles

The Clinical Association and Prognostic Impact of IL1RAP Expression in Patients with De Novo Acute Myeloid Leukemia

Chao-Hung Wei, MD, Cheng-Hong Tsai, MD, M.Sc., Jih-Luh Tang, MD, PhD, Yuan-Yeh Kuo, PhD, Feng-Ming Tien, MD, M.Sc, Chien-Chin Lin, MD, Mei-Hsuan Tseng, M.Sc., Yen-Ling Peng, Ming-Chih Liu, Chia-Wen Liu, Ming Yao, MD, Liang-In Lin, PhD, Wen-Chien Chou, MD, PhD, Chien-Yu Chen, PhD, Hsin-An Hou, Hwei-Fang Tien, MD, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2705.
https://doi.org/10.1182/blood-2019-124657
Published: 2019
Journal Articles

Metabolic Alterations May Contribute to Cabozantinib Resistance in Acute Myeloid Leukemia Cells with FLT3 -ITD

Fang-Yu Lo, Kit Man Ng, MS, Wen-Chun Chen, MS, Chung-Yi Hu, PhD, Hsin-An Hou, MD PhD, Cheng-Hong Tsai, MD, M.Sc., Da-Liang Ou, PhD, Hwei-Fang Tien, MD, PhD, Liang-In Lin, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2785.
https://doi.org/10.1182/blood-2018-99-118322
Published: 2018
Journal Articles

Pyrvinium Pamoate Overcomes Cabozantinib-Resistance of FLT3 -ITD AML Cells through Modulating the Mitochondria Functions and Signaling Pathways

Yu-Hsuan Fu, BS, Wen-Hui Lu, MS, Pei-Qi Lan, MS, Chung-Yi Hu, PhD, Chien-Yuan Chen, MD, PhD, Da-Liang Ou, PhD, Hwei-Fang Tien, MD, PhD, Liang-In Lin, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4683.
https://doi.org/10.1182/blood-2018-99-118476
Published: 2018
Journal Articles

Botanical Alkyl Hydroquinone Derivative HQ17(3) Induces Calcium-Associated Mitochondrial Damage and Mitophagy to Exert Ctotoxicity to Philadelphila Chromosome(+) ALL Cells

Yin-Chen Chou, MS, Chia-Wei Chen, MS, Yuan-Yeh Kuo, PhD, Liang-In Lin, PhD, Chung-Yi Hu, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5800.
https://doi.org/10.1182/blood-2018-99-120307
Published: 2018
Journal Articles

Prognostic Impacts and Dynamic Changes of Cohesin Complex Gene Mutations in De Novo Acute Myeloid Leukemia

Cheng-Hong Tsai, MD, M.Sc., Hsin-An Hou, MD, PhD, Jih-Luh Tang, MD,PhD, Yuan-Yeh Kuo, PhD, Yu-Chiao Chiu, PhD, Chien-Chin Lin, MD, Liang-In Lin, PhD, Ming Yao, MD, Chi-Cheng Li, MD, Shang-Yi Huang, MD, PhD, Bor-Sheng Ko, MD, PhD, Szu Chun Hsu, MD, Chien-Ting Lin, MD, Shang-Ju Wu, MD, PhD, Chien-Yuan Chen, MD, PhD, Woei Tsai, MD, PhD, Wen-Chien Chou, MD, PhD, Hwei-Fang Tien, MD, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2582.
https://doi.org/10.1182/blood.V130.Suppl_1.2582.2582
Published: 2017
Journal Articles

DNMT3A mutations in acute myeloid leukemia: stability during disease evolution and clinical implications

Hsin-An Hou, Yuan-Yeh Kuo, Chieh-Yu Liu, Wen-Chien Chou, Ming Cheng Lee, Chien-Yuan Chen, Liang-In Lin, Mei-Hsuan Tseng, Chi-Fei Huang, Ying-Chieh Chiang, Fen-Yu Lee, Ming-Chih Liu, Chia-Wen Liu, Jih-Luh Tang, Ming Yao, Shang-Yi Huang, Bor-Sheng Ko, Szu-Chun Hsu, Shang-Ju Wu, Woei Tsay, Yao-Chang Chen, Hwei-Fang Tien
Journal: Blood
Blood (2012) 119 (2): 559–568.
https://doi.org/10.1182/blood-2011-07-369934
Published: 2012
Includes: Supplemental data
Journal Articles

DNMT3A Mutations in Acute Myeloid Leukemia-Stability During Disease Evolution and the Clinical Implication

Hsin-An Hou, MD, Yuan-Yeh Kuo, Chieh-Yu Liu, Wen-Chien Chou, MD, PhD, Ming Cheng Lee, Chien-Yuan Chen, Liang-In Lin, PhD, Mei-Hsuan Tseng, Chi-Fei Huang, Ying-Chieh Chiang, Fen-Yu Lee, Ming-Chih Liu, Chia-Wen Liu, Jih-Luh Tang, MD, PhD, Ming Yao, MD, Shang-Yi Huang, MD, PhD, Bor-Sheng Ko, Szu-Chun Hsu, Shang-Ju Wu, Woei Tsay, Yao-Chang Chen, Hwei-Fang Tien, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 409.
https://doi.org/10.1182/blood.V118.21.409.409
Published: 2011
Journal Articles

WT1 mutation in 470 adult patients with acute myeloid leukemia: stability during disease evolution and implication of its incorporation into a survival scoring system

Hsin-An Hou, Tai-Chung Huang, Liang-In Lin, Chieh-Yu Liu, Chien-Yuan Chen, Wen-Chien Chou, Jih-Luh Tang, Mei-Hsuan Tseng, Chi-Fei Huang, Ying-Chieh Chiang, Fen-Yu Lee, Ming-Chih Liu, Ming Yao, Shang-Yi Huang, Bor-Sheng Ko, Szu-Chun Hsu, Shang-Ju Wu, Woei Tsay, Yao-Chang Chen, Hwei-Fang Tien
Journal: Blood
Blood (2010) 115 (25): 5222–5231.
https://doi.org/10.1182/blood-2009-12-259390
Published: 2010
Includes: Supplemental data
Journal Articles

AML1/RUNX1 mutations in 470 adult patients with de novo acute myeloid leukemia: prognostic implication and interaction with other gene alterations

Jih-Luh Tang, Hsin-An Hou, Chien-Yuan Chen, Chieh-Yu Liu, Wen-Chien Chou, Mei-Hsuan Tseng, Chi-Fei Huang, Fen-Yu Lee, Ming-Chih Liu, Ming Yao, Shang-Yi Huang, Bor-Sheng Ko, Szu-Chun Hsu, Shang-Ju Wu, Woei Tsay, Yao-Chang Chen, Liang-In Lin, Hwei-Fang Tien
Journal: Blood
Blood (2009) 114 (26): 5352–5361.
https://doi.org/10.1182/blood-2009-05-223784
Published: 2009
Includes: Supplemental data
Journal Articles

AML1/RUNX1 Mutations in 470 Adult Patients with De Novo Acute Myeloid Leukemia: Prognostic Implication and Interaction with Other Gene Alterations.

Hsin An Hou, Jih-Luh Tang, Liang-In Lin, PhD, Chien-Yuan Chen, Wen-Chien Chou, Mei-Hsuan Tseng, Chi-Fei Huang, Fen-Yu Lee, Ming-Chih Liu, Ming Yao, Shang-Yi Huang, MD, Bo-Sheng Ko, Szu-Chun Hsu, Shang-Ju Wu, Woei Tsai, Yao-Chang Chen, Hwei-Fang Tien
Journal: Blood
Blood (2009) 114 (22): 1564.
https://doi.org/10.1182/blood.V114.22.1564.1564
Published: 2009
Journal Articles

CEBPA Methylation as a Prognostic Biomarker in Adult Patients with De Novo AML.

Hsin-Yu Chen, Tsung-Chin Lin, Wen-Chien Chou, Hsin-An Hou, Hwei-Fang Tien, Liang-In Lin, PhD
Journal: Blood
Blood (2009) 114 (22): 1569.
https://doi.org/10.1182/blood.V114.22.1569.1569
Published: 2009
Journal Articles

Role of Gene Mutations in Adult Acute Myeloid Leukemia Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation.

Sheng-Chieh Chou, Jih-Luh Tang, MD, PhD, Liang-In Lin, PhD, Hsin-An Hou, Chien-Yuan Chen, Szu-Chun Hsu, Bo-Sheng Ko, Shang-Yi Huang, MD, Wen-Chien Chou, Ming Yao, Woei Tsay, Yao-Chang Chen, Hwei-Fang Tien
Journal: Blood
Blood (2009) 114 (22): 3373.
https://doi.org/10.1182/blood.V114.22.3373.3373
Published: 2009
Journal Articles

Methylation Status of miRNA Let-7a-3 in Acute Myeloid Leukemia

Tsung-Chin Lin, Yong-Sian Chen, Hsin-An Hou, Wen-Chien Chou, Jih-Luh Tang, MD, PhD, Hwei-Fang Tien, Liang-In Lin, PhD
Journal: Blood
Blood (2008) 112 (11): 4482.
https://doi.org/10.1182/blood.V112.11.4482.4482
Published: 2008
Journal Articles

Hierarchical Cluster Analysis of Immunophenotype in AML Patients with NPM1 Gene Mutation Reveals Two Distinct Groups with Different Prognosis.

Chien-Yuan Chen, Liang-In Lin, PhD, Wen-Chien Chou, Woei Tsay, Jih-Luh Tang, Sheng-Yi Huang, Hwei-Fang Tien
Journal: Blood
Blood (2008) 112 (11): 1495.
https://doi.org/10.1182/blood.V112.11.1495.1495
Published: 2008
Journal Articles

Clinical and Biological Characterization of Adult Patients with Acute Myeloid Leukemia Bearing T(7;11)(p15;p15)—Analysis of 536 Patients

Wen-Chien Chou, Chien-Yuan Chen, Hsin-An Hou, Liang-In Lin, Jih-Luh Tang, Ming Yao, Woei Tsay, Bor-Shen Ko, Shan-Yi Huang, Hwei-Fang Tien
Journal: Blood
Blood (2008) 112 (11): 2535.
https://doi.org/10.1182/blood.V112.11.2535.2535
Published: 2008