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Journal Articles

PARP1 inhibition sensitizes AML to CD123 CAR-NK cells via immunophenotypic remodeling

Lea Kramer, Saskia Rudat, Shalini Ramachandran, Anna Stanger, Luca Hensen, Rimas Orentas, Congcong Zhang, Dominika Lukas, Fenja Gierschek, Evelyn Ullrich, Claudia Lengerke

Blood (2025) 146 (Supplement 1): 2357.

https://doi.org/10.1182/blood-2025-2357

Published: 2025

Journal Articles

The laminin receptor integrin α7β1 marks a highly migratory cell population and correlates with poor prognosis in Acute Myeloid Leukemia.

Saskia Rudat, Elsa Görsch, Marlon Arnone, Hildegard Keppeler, Nandini Asokan, Jan Christian Schroeder, Taylor Mills, Lea Kramer, Jan Pauluschke-Fröhlich, Maksim Klimiankou, Jan Weller, Gerd Klein, Claudia Lengerke

Blood (2025) 146 (Supplement 1): 3491.

https://doi.org/10.1182/blood-2025-3491

Published: 2025

Journal Articles

Defining a high-risk population for CAR-T-cell therapy: The impact of clonal hematopoiesis and pre-existing neutropenia on severe outcomes in patients treated for malignant and non-malignant conditions

Alisha Weiss-Haug, Reka Haraszti, Jan Christian Schroeder, Kristina Reuß, Britta Merz, Saskia Rudat, Hildegard Keppeler, Lea Kramer, Elena Mirovic, Christoph Faul, Ann-Christin Pecher, Joerg Henes, Katrin Lutz, Luca Hensen, Wolfgang Bethge, Friederike Schwartz, Claudia Lengerke

Blood (2025) 146 (Supplement 1): 5942.

https://doi.org/10.1182/blood-2025-5942

Published: 2025