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Hildegard Keppeler
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Journal Articles

Characterization of a Human Bone Marrow-Derived CRISPR/Cas9 Cell Model for Chronic Myeloid Leukemia

Pia Christin Radszuweit, Barbara Mankel, Fulya Korkmaz, Hildegard Keppeler, Claudia Lengerke, Dominik Schneidawind, Corina Schneidawind
Journal: Blood
Blood (2024) 144 (Supplement 1): 1353.
https://doi.org/10.1182/blood-2024-209947
Published: 2024
Journal Articles

Induction of t(9;22) (q34;q11) in Bone Marrow-Derived HSPCs Via CRISPR/Cas9 to Reveal the Differences of the Leukemogenic Properties of p210 BCR/ABL1 and p185 BCR/ABL1

Pia Radszuweit, Fulya Korkmaz, Barbara Mankel, Rahel Fitzel, Estelle Erkner, Hildegard Keppeler, Claudia Lengerke, Dominik Schneidawind, Corina Schneidawind
Journal: Blood
Blood (2022) 140 (Supplement 1): 5879.
https://doi.org/10.1182/blood-2022-169414
Published: 2022
Journal Articles

Different MLL Breakpoints Influence Leukemia Characteristics of MLL -Rearranged Cells in a Human CRISPR/Cas9-Based Model

Rahel Fitzel, Sarah Brüstl, Fulya Korkmaz, Barbara Mankel, Estelle Erkner, Hildegard Keppeler, Claudia Lengerke, Dominik Schneidawind, Corina Schneidawind
Journal: Blood
Blood (2022) 140 (Supplement 1): 5857.
https://doi.org/10.1182/blood-2022-169461
Published: 2022
Journal Articles

The Rorɣ/SREBP2 Pathway Is a Master Regulator of Cholesterol Metabolism and Serves As Potential Therapeutic Target in T(4;11) Leukemia

Estelle Erkner, Thomas Hentrich, Rahel Fitzel, Hildegard Keppeler, Fulya Korkmaz, Johan Jeong, Julia Schulze-Hentrich, Claudia Lengerke, Dominik Schneidawind, Corina Schneidawind
Journal: Blood
Blood (2022) 140 (Supplement 1): 2999–3000.
https://doi.org/10.1182/blood-2022-169267
Published: 2022
Journal Articles

Inhibition of DOT1L and PRMT5 Promotes Anti-Tumor Activity in a Human MLL Leukemia Model Induced By CRISPR/Cas9

Kathy-Ann Secker, MSc, Hildegard Keppeler, Silke Duerr-Stoerzer, Hannes Schmid, MSc, Dominik Schneidawind, MD, Thomas Hentrich, PhD, Julia Schulze-Hentrich, PhD, Barbara Mankel, Falko Fend, MD, Lothar Kanz, Corina Schneidawind, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5147.
https://doi.org/10.1182/blood-2018-99-115975
Published: 2018
Journal Articles

Invariant Natural Killer T Cells from Donor Lymphocyte Infusions (DLI-iNKTs) Contribute to Anti-Tumor Immunity after Allogeneic Hematopoietic Cell Transplantation

Simona Jahnke, Hannes Schmid, MSc, Kathy-Ann Secker, MSc, Silke Duerr-Stoerzer, Hildegard Keppeler, Rebecca Baur, Michael Schumm, Dr. MD vet., Rupert Handgretinger, MD PhD, Wolfgang Bethge, MD, Lothar Kanz, Corina Schneidawind, MD, Dominik Schneidawind, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3340.
https://doi.org/10.1182/blood-2018-99-111745
Published: 2018
Journal Articles

Myc Drives MLL Leukemogenesis in a Human CRISPR/Cas9 Leukemia Model and Indirect Inhibition with JQ1 Diminishes Leukemia Activity

Kathy-Ann Secker, MSc, Hildegard Keppeler, Silke Duerr-Stoerzer, Hannes Schmid, MSc, Dominik Schneidawind, MD, Thomas Hentrich, PhD, Julia Schulze-Hentrich, PhD, Lothar Kanz, Corina Schneidawind, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2213.
https://doi.org/10.1182/blood-2018-99-114419
Published: 2018
Journal Articles

Engraftment of Human Mesenchymal Stem Cells upon Transplantation into Newborn Rag2−/−gc−/− Mice.

Patrick Ziegler, PhD, Steffen Boettcher, Hildegard Keppeler, Bettina Kirchner, Markus G. Manz, MD
Journal: Blood
Blood (2006) 108 (11): 1652.
https://doi.org/10.1182/blood.V108.11.1652.1652
Published: 2006