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L. Bik To, MD
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Journal Articles

Metabolic Profiling of Adult Acute Myeloid Leukemia (AML)

Mahmoud A Bassal, Bsc, BCompSc, Paul Leo, PhD, Saumya E Samaraweera, PhD, Kyaw Ze Ya Maung, BSc, Milena Babic, Parvathy Venugopal, BSc, Jesse Cheah, BSc, Christopher N Hahn, PhD, Hamish S Scott, BSc, PhD FFSc (RCPA), Evgeny Glazov, PhD, Sarah C Bray, PhD, Diana Iarossi, Ing Soo Tiong, MBChB, Mhairi Clout, MSc, Emma Duncan, PhD, L. Bik To, MD, Paula Marlton, MBBS, FRACP, FRCPA, Ian D Lewis, MBBS, PhD FRACP, FRCPA, Devinder S Gill, MBChB FRCPath MRCP, Thomas J Gonda, PhD, Anna L Brown, PhD, Richard D'Andrea, PhD
Journal: Blood
Blood (2016) 128 (22): 1684.
https://doi.org/10.1182/blood.V128.22.1684.1684
Published: 2016
Journal Articles

Divergent Dynamics of Epigenetic and Genetic Heterogeneity in Relapsed Acute Myeloid Leukemia

Francine E. Garrett-Bakelman, MD PhD, Sheng Li, PhD, Stephen S. Chung, MD, Todd Hricik, Rapaport Franck, Jay Patel, Richard Dillon, MA, MRCP, FRCPath, Priyanka Vijay, Anna L Brown, PhD, Alexander E. Perl, MD, B. Joy Cannon, Mathijs A. Sanders, PhD, Peter J M Valk, PhD, Lars Bullinger, MD, Selina Luger, MD, Michael W. Becker, MD, Ian D. Lewis, MBBS PhDFRACP FRCPA, L. Bik To, MD, Richard J D'Andrea, PhD, David Grimwade, MD PhD, Ruud Delwel, PhD, Bob Lowenberg, MD PhD, Hartmut Dohner, MD, Konstanze Dohner, MD, Duane C Hassane, PhD, Monica L. Guzman, PhD, Gail J Roboz, MD, Martin Carroll, MD, Christopher Y. Park, MD, PhD, Donna S. Neuberg, Sc.D., Ross L. Levine, MD, Christopher Mason, PhD, Ari Melnick, MD
Journal: Blood
Blood (2015) 126 (23): 306.
https://doi.org/10.1182/blood.V126.23.306.306
Published: 2015
Journal Articles

Methylation of the Proximal Promoter of GADD45A Is Common in Acute Myeloid Leukemia and Is Associated with Poor Survival.

Richard J D'Andrea, PhD, Michelle Perugini, PhD, Sonya M Diakiw, PhD, Chung H Kok, PhD, Diana Salerno, Nik Cummings, BSc, Anna L Brown, PhD, Silke Danner, Peter G Bardy, MBBS, FRACP, FRCPA, Andrew H Wei, MBBS, PhD, L. Bik To, MD, Ian D Lewis, MBBS, PhD
Journal: Blood
Blood (2012) 120 (21): 2396.
https://doi.org/10.1182/blood.V120.21.2396.2396
Published: 2012
Journal Articles

A Regulatory Promoter Polymorphism and Hypermethylation of Intron 1 Are Associated with Reduced Expression of KLF5 and Inferior Survival in AML

Anna L Brown, PhD, Sonya M Diakiw, PhD, Michelle Perugini, PhD, Nik Cummings, BSc, Andrew H Wei, MBBS, PhD, L. Bik To, MD, Ian D Lewis, MBBS, PhD, Richard J D'Andrea, PhD
Journal: Blood
Blood (2012) 120 (21): 3508.
https://doi.org/10.1182/blood.V120.21.3508.3508
Published: 2012
Journal Articles

Expression of Erythroid Transcription Factors Are Decreased in a RPS19 Knockdown Cell Line Model of Diamond Blackfan Anaemia

Sarah C E Bray, PhD, Amilia Wee, BSc (hons), Michelle Perugini, PhD, L. Bik To, MD, Richard J D'Andrea, PhD
Journal: Blood
Blood (2012) 120 (21): 3473.
https://doi.org/10.1182/blood.V120.21.3473.3473
Published: 2012
Journal Articles

Methylation of a Single CpG in the GADD45A Proximal Promoter Is Associated with Poor Survival in Acute Myeloid Leukemia,

Richard J D'Andrea, PhD, Michelle Perugini, PhD, Chung H Kok, PhD, Diana Salerno, Silke Danner, Peter G Bardy, MBBS, FRACP, FRCPA, Andrew H Wei, MBBS, PhD, L. Bik To, MD, Ian D Lewis, MBBS, PhD
Journal: Blood
Blood (2011) 118 (21): 3540.
https://doi.org/10.1182/blood.V118.21.3540.3540
Published: 2011
Journal Articles

GATA2 is a New Predisposition Gene for Familial Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)

Hamish S Scott, PhD, Christopher N Hahn, PhD, Catherine L Carmichael, PhD, Ella J Wilkins, BSc(Hon), Chan-Eng Chong, MSc, Peter J Brautigan, BSc(Hon), Xiao-Chun Li, MSc, Milena Stankovic, BSc(Hon), Ming Lin, BSc(Hon), Amandine Carmagnac, BSc, Carolyn M Butcher, MMedSc(Hon), Kathryn L Friend, PhD, Paul G Ekert, MBBS, PhD, Chung H Kok, BSc(Hon), Anna L Brown, PhD, Ian D Lewis, MBBS, PhD, L. Bik To, MD, Andrew E Timms, PhD, Jan Storek, MD, PhD, Sarah Moore, BSc(Hon), Meryl Altree, BNg, Robert Escher, MD, Peter G Bardy, MBBS, Graeme K Suthers, MBBS, PhD, Richard J D'Andrea, PhD, Marshall S Horwitz, MD, PhD
Journal: Blood
Blood (2010) 116 (21): LBA-3.
https://doi.org/10.1182/blood.V116.21.LBA-3.LBA-3
Published: 2010
Journal Articles

Expression Profiling of a Hemopoietic Cell Survival Transcriptome Identifies a Functional Prognostic Gene Signature in Normal Karyotype AML.

Mark Guthridge, Daniel Thomas, MD, Emma F Barry, Kok H Chung, Barbara J McClure, L. Bik To, MD, Greg Goodall, Terry P Speed, Motomi Osato, David Haylock, Susie Nilsson, MD, Richard D'Andrea, PhD, Angel Lopez, Jason A Powell, PhD
Journal: Blood
Blood (2009) 114 (22): 1618.
https://doi.org/10.1182/blood.V114.22.1618.1618
Published: 2009
Journal Articles

Blocking of Cytokine Survival Signals along with Intense Bcr-Abl Kinase Inhibition May Eradicate CML Progenitor Cells.

Devendra K Hiwase, MD, Deborah L White, PhD, Jason A Powell, PhD, Verity A Saunders, Stephanie Zrim, Amity Frede, Mark Guthridge, Richard D'Andrea, PhD, L. Bik To, MD, Junia V. Melo, MD, PhD, Sharad Kumar, PhD, Timothy Hughes, MD
Journal: Blood
Blood (2009) 114 (22): 3250.
https://doi.org/10.1182/blood.V114.22.3250.3250
Published: 2009
Journal Articles

In Contrast to Imatinib, OCT-1 Mediated Influx Has Minimal Impact on Cellular Uptake of Dasatinib in CML Patients at Diagnosis.

Devendra K. Hiwase, MD, Deborah L. White, Verity A. Saunders, Phuong Dang, Amity Venables, Laura Eadie, Steph Zrim, L. Bik To, MD, Junia V. Melo, MD, Timothy P. Hughes, MD
Journal: Blood
Blood (2007) 110 (11): 1937.
https://doi.org/10.1182/blood.V110.11.1937.1937
Published: 2007