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Journal Articles

Prochemerin cleavage by factor XIa links coagulation and inflammation

Xiaomei Ge, Yasuto Yamaguchi, Lei Zhao, Loredana Bury, Paolo Gresele, Caroline Berube, Lawrence L. Leung, John Morser
Journal: Blood
Blood (2018) 131 (3): 353–364.
https://doi.org/10.1182/blood-2017-07-792580
Published: 2018
Includes: Supplemental data
Journal Articles

Prochemerin Cleavage By Factor XIa Links Adipogenesis, Inflammation and Coagulation

Xiaomei Ge, PhD, Yasuto Yamaguchi, Lei Zhao, MS, Loredana Bury, Paolo Gresele, Lawrence L. Leung, John Morser, PhD
Journal: Blood
Blood (2016) 128 (22): 2561.
https://doi.org/10.1182/blood.V128.22.2561.2561
Published: 2016
Journal Articles

Deficiency of Either Carboxypeptidase B2 or Carboxypeptidase N Exacerbated Disease Activity in a Mouse Model of Hemolytic Uremic Syndrome

Lawrence L. Leung, MD, Zhifei Shao, MD PhD, Toshihiko Nishimura, PhD, Qin Zhou, PhD, Laura Gigliello, Peter Castro, John Higgins, John Morser, PhD
Journal: Blood
Blood (2016) 128 (22): 3758.
https://doi.org/10.1182/blood.V128.22.3758.3758
Published: 2016
Journal Articles

Carboxypeptidase B2 Is Protective in a Mouse Model of Shiga Toxin-Induced Hemolytic Uremic Syndrome

Toshihiko Nishimura, PhD, John Morser, PhD, Zhifei Shao, MD PhD, Lawrence L. Leung, MD
Journal: Blood
Blood (2014) 124 (21): 2804.
https://doi.org/10.1182/blood.V124.21.2804.2804
Published: 2014
Journal Articles

GPR84 sustains aberrant β-catenin signaling in leukemic stem cells for maintenance of MLL leukemogenesis

Philipp A. Dietrich, Chen Yang, Halina H. L. Leung, Jennifer R. Lynch, Estrella Gonzales, Bing Liu, Michelle Haber, Murray D. Norris, Jianlong Wang, Jenny Yingzi Wang
Journal: Blood
Blood (2014) 124 (22): 3284–3294.
https://doi.org/10.1182/blood-2013-10-532523
Published: 2014
Includes: Supplemental data
Journal Articles

CPB2 Deficiency Protects Against Polymicrobial Sepsis

Zhifei Shao, MD, PhD, Toshihiko Nishimura, PhD, Lawrence L. Leung, MD, John Morser, PhD
Journal: Blood
Blood (2012) 120 (21): 1110.
https://doi.org/10.1182/blood.V120.21.1110.1110
Published: 2012
Journal Articles

Chemerin Bioactivity Is Regulated by Factor XIa: A Novel Interface Linking Between Coagulation, Hemostasis and Immunity

Yasuto Yamaguchi, PhD, John Morser, PhD, Lawrence L. Leung, MD
Journal: Blood
Blood (2011) 118 (21): 2258.
https://doi.org/10.1182/blood.V118.21.2258.2258
Published: 2011
Journal Articles

Prochemerin Is a New Substrate for Thrombin.

Xiaoyan Du, PhD, Timothy Myles, PhD, John Morser, PhD, Lawrence L. Leung, MD
Journal: Blood
Blood (2009) 114 (22): 3591.
https://doi.org/10.1182/blood.V114.22.3591.3591
Published: 2009
Journal Articles

The impact of Fc engineering on an anti-CD19 antibody: increased Fcγ receptor affinity enhances B-cell clearing in nonhuman primates

Jonathan Zalevsky, Irene W. L. Leung, Sher Karki, Seung Y. Chu, Eugene A. Zhukovsky, John R. Desjarlais, David F. Carmichael, Chris E. Lawrence
Journal: Blood
Blood (2009) 113 (16): 3735–3743.
https://doi.org/10.1182/blood-2008-10-182048
Published: 2009
Journal Articles

Differentially Cleaved Forms of Osteopontin by Thrombin and Carboxypeptidase B (TAFIa) Regulates Neutrophil Viability and Synoviocyte Binding in Rheumatoid Arthritis

Shadi Sharif, MS, Xiaoyan Du, PhD, Timothy Myles, PhD, Jason Jungsik Song, MD, Elizabeth A Price, MD, MPH, David Lee, MD, PhD, Stuart Goodman, MD, John Morser, PhD, William Robinson, MD, PhD, Lawrence L. Leung, MD
Journal: Blood
Blood (2008) 112 (11): 3562.
https://doi.org/10.1182/blood.V112.11.3562.3562
Published: 2008
Journal Articles

Platelet Interaction with Bone Marrow Derived CD34 + Stem Cells: Potential Role of Chemoattractant Chemerin

Xiao-Yan Du, PhD, Lawrence L. Leung, MD
Journal: Blood
Blood (2008) 112 (11): 3930.
https://doi.org/10.1182/blood.V112.11.3930.3930
Published: 2008
Journal Articles

Thrombin-Cleaved Osteopontin Is Regulated by Thrombin-Activatable Carboxypeptidase B in Rheumatoid Arthritis.

Timothy Myles, PhD, Shadi A. Sharif, BS, Xiao-Yan Du, PhD, Jason J. Song, MD, Price Elizabeth, MD, William H. Robinson, MD, Lawrence L. Leung, MD
Journal: Blood
Blood (2007) 110 (11): 1744.
https://doi.org/10.1182/blood.V110.11.1744.1744
Published: 2007
Journal Articles

Regulation of Chemerin Bioactivity by Plasma Carboxypeptidase N, Carboxypeptidase B (TAFIa) and Platelets.

Xiao-Yan Du, PhD, Brian A. Zabel, PhD, Samantha J. Allen, PhD, Tracy M. Handel, PhD, Peter P. Lee, PhD/MD, Eugene C. Butcher, MD, Lawrence L. Leung, MD
Journal: Blood
Blood (2007) 110 (11): 408.
https://doi.org/10.1182/blood.V110.11.408.408
Published: 2007
Journal Articles

Mechanism of Interaction between the Heavy Chain of Factor VIII and Thrombin.

Keiji Nogami, M.D./Ph. D., Qian Zhou, Hironao Wakabayashi, Ph.D., Timothy Myles, Ph.D., Lawrence L. Leung, M. D., Philip J. Fay, Ph. D.
Journal: Blood
Blood (2004) 104 (11): 1711.
https://doi.org/10.1182/blood.V104.11.1711.1711
Published: 2004
Journal Articles

Essential Thrombin Residues for Inhibition by Plasminogen Activator Inhibitor-1 in the Absence and Presence of Heparin and Vitronectin.

Yolanda M. Fortenberry, Ph.D., Jill C. Rau, Lauren C. Cranford, Timothy Myles, Ph.D., Lawerence L. Leung, M.D., Frank C. Church, Ph.D.
Journal: Blood
Blood (2004) 104 (11): 3986.
https://doi.org/10.1182/blood.V104.11.3986.3986
Published: 2004
Journal Articles

Heparin binds to human monocytes and modulates their procoagulant activities and secretory phenotypes. Effects of histidine-rich glycoprotein

L Leung, K Saigo, D Grant
Journal: Blood
Blood (1989) 73 (1): 177–184.
https://doi.org/10.1182/blood.V73.1.177.177
Published: 1989