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Journal Articles

Molecular Mechanisms Associated with Autophagy Inhibition to Overcome Resistance to FLT3 Inhibitors

Manuela Albuquerque De Melo, Diego A. Pereira-Martins, Brunno Gilberto Santos Macedo, Livia Bassani Lins de Miranda, Priscila Santos Scheucher, Isabel Weinhäuser, Gerwin Huls, Jan Jacob Schuringa, João Agostinho Machado-Neto, Fabiola Traina

Blood (2024) 144 (Supplement 1): 2752.

https://doi.org/10.1182/blood-2024-203390

Published: 2024

Journal Articles

Potency and Efficacy of Pharmacological PIP4K2 Inhibitors in Acute Lymphoblastic Leukemia

Keli Lima, Maria Fernanda Lopes Carvalho, Diego A. Pereira-Martins, Wellington F Silva, Mariane Cristina do Nascimento, Lívia Bassani Lins de Miranda, Rita de Cássia Cavaglieri Medeiros, Luciana Nardinelli, Aline de Medeiros Leal, Elvira Deolinda Rodrigues Pereira Velloso, Israel Bendit, Jan Jacob Schuringa, João Agostinho Machado-Neto, Eduardo Magalhães Rego

Blood (2023) 142 (Supplement 1): 5786.

https://doi.org/10.1182/blood-2023-189786

Published: 2023

Journal Articles

Identification of Vulnerabilities for Pharmacological Inhibition of PIP4K2s in Acute Myeloid Leukemia

Keli Lima, Maria Fernanda Lopes Carvalho, Diego A Pereira-Martins, Lívia Bassani Lins de Miranda, Mariane Cristina do Nascimento, Frederico Lisboa Nogueira, Rita de Cássia Cavaglieri Medeiros, Jan Jacob Schuringa, João Agostinho Machado-Neto, Eduardo Magalhães Rego

Blood (2023) 142 (Supplement 1): 5774.

https://doi.org/10.1182/blood-2023-189998

Published: 2023

Journal Articles

Targeting PIP4K2 Lipid Kinases through Thz-P1-2 Reveals Vulnerabilities Related to Mitochondrial Homeostasis and Autophagy in Acute Leukemia

Keli Lima, Diego A Pereira-Martins, Lívia Bassani Lins de Miranda, Juan L Coelho-Silva, Giovana da Silva Leandro, Isabel Weinhäuser, Rita de Cassia Cavaglieri, Wellington F Silva, Aline Medeiros Leal, Ana Paula Alencar de Lima Lange, Elvira Deolinda Rodrigues Pereira Velloso, Emmanuel Griessinger, Jacobien R Hilberink, Gerwin A. Huls, Jan Jacob Schuringa, João Agostinho Machado-Neto, Eduardo M Rego

Blood (2022) 140 (Supplement 1): 5965–5966.

https://doi.org/10.1182/blood-2022-165172

Published: 2022