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Journal Articles

Single-Cell Transcriptomic Profiling of De Novo and Relapsed Acute Myeloid Leukemia Identifies a Leukemic Stemness Program Shared across Diverse Phenotypes

Samantha Worme, BSc, Selin Jessa, BSc, William Poon, BSc, Maja Jankovic, MSc, Gabriela Galicia Vazquez, PhD, Alexandre Bazinet, MD, Katharine Fooks, BSc, Isabella Iasenza, BSc, Patricia Arreba-Tutusaus, PhD, Kolja Eppert, PhD, Ioannis Ragoussis, PhD, Yu Chang Wang, PhD, Nathalie A Johnson, MD PhD, Sarit E Assouline, MD MSc, Claudia L Kleinman, PhD, François E Mercier, MD

Blood (2020) 136 (Supplement 1): 1.

https://doi.org/10.1182/blood-2020-143221

Published: 2020

Journal Articles

CD200 Is a Marker of LSC Activity in Acute Myeloid Leukemia

Jenny M. Ho, MD, Stephanie M. Dobson, Jessica McLeod, Liqing Jin, MD PhD, Stanley W.K. Ng, MSc, Amanda Mitchell, PhD, Liran I. Shlush, MD PhD, Sasan Zandi, MD PhD, Kolja Eppert, PhD, Mark D. Minden, MD PhD, John E. Dick, PhD, Jean C.Y. Wang, MD PhD

Blood (2016) 128 (22): 1705.

https://doi.org/10.1182/blood.V128.22.1705.1705

Published: 2016

Journal Articles

Identification of Existing Bioactive Compounds That Target Acute Myeloid Leukemia Stem Cells

Isabelle Laverdiere, B.Pharm, PhD, Andrea L. Neumann, BSc, Meaghan Boileau, BSc, Heather Duncan, MSc, Sara Chisling, Amanda Mithchell, PhD, Stanley W.K. Ng, MSc, Jean C.Y. Wang, MDPhD, Mark D. Minden, MD PhD, John E. Dick, PhD, Kolja Eppert, PhD

Blood (2015) 126 (23): 3681.

https://doi.org/10.1182/blood.V126.23.3681.3681

Published: 2015

Journal Articles

G Protein-Coupled Receptor 56 As a Potential Regulator of Normal and Leukemic Stem Cells

Heather Duncan, MSc, Karin G. Hermans, PhD, Sara Chisling, Isabelle Laverdiere, B.Pharm, PhD, Mark D. Minden, MD PhD, John E. Dick, PhD, Kolja Eppert, PhD

Blood (2015) 126 (23): 4267.

https://doi.org/10.1182/blood.V126.23.4267.4267

Published: 2015

Journal Articles

Gene Expression and Mutation Analysis (GEMA) –Guided Precision Medicine Targeting PARP1 to Induce Synthetic Lethality in DNA-PK –Deficient Quiescent and BRCA-Deficient Proliferating Leukemia Stem and Progenitor Cells

Margaret Nieborowska-Skorska, MD PhD, Katherine Sullivan, Paulina Podszywalow-Bartnicka, Grazyna Hoser, PhD, Elisabeth Bolton-Gillespie, Kimberly Cramer-Morales, Artur Slupianek, PhD, Chun Zhou, PhD, Sabine Cerny-Reiterer, DVM, Tomasz Stoklosa, MD PhD, Stephen M. Sykes, PhD, Peter Valent, MD, Curt I. Civin, MD, Markus Muschen, MD PhD, Mark D. Minden, MD PhD, Kolja Eppert, PhD, Tomasz Skorski, MD PhD

Blood (2014) 124 (21): 480.

https://doi.org/10.1182/blood.V124.21.480.480

Published: 2014

Journal Articles

Mir-126 Governs Human Leukemia Stem Cell Quiescence and Chemotherapy Resistance

Eric R. Lechman, PhD, Bernhard Gentner, MD, Peter van Galen, Stanley Wai-Kwong Ng, Kolja Eppert, PhD, Rene Marke, Liran Slush, MD, James A. Kennedy, MD PhD, Amanda Mitchell, PhD, Weihsu Claire Chen, PhD, Veronique Voisin, PhD, Gary Bader, PhD, Mark D. Minden, MD, PhD, Jun Lu, PhD, Jean C.Y. Wang, MD PhD, Luigi Naldini, John E. Dick, PhD

Blood (2013) 122 (21): 1647.

https://doi.org/10.1182/blood.V122.21.1647.1647

Published: 2013

Journal Articles

Discovery of Novel Recurrent Mutations in Childhood Early T-Cell Precursor Acute Lymphoblastic Leukemia by Whole Genome Sequencing - a Report From the St Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project

Jinghui Zhang, PhD, Li Ding, PhD, Linda Holmfeldt, PhD, Gang Wu, PhD, Susan L. Heatley, Ph.D., Debbie Payne-Turner, John Easton, PhD, Xiang Chen, PhD, Jianmin Wang, PhD, Michael Rusch, BA, Charles Lu, PhD, Shann-Ching Chen, PhD, Racquel Collins-Underwood, PhD, Jing Ma, PhD, Kathryn G. Roberts, PhD, Stanley Pounds, PhD, Lei Wei, PhD, Anatoly Ulyanov, PhD, Jared Becksfort, Pankaj Gupta, Robert Huether, PhD, Richard Kriwacki, PhD, Daniel McGoldrick, David Zhao, Daniel Alford, Stephen Espy, Kiran Chand Bobba, Guangchun Song, Deqing Pei, MS, Cheng Cheng, PhD, Stefan Roberts, Michael Barbato, Dario Campana, MD, PhD, Elaine Coustan-Smith, MS, William E. Evans, PharmD, Sheila A Shurtleff, PhD, Maria Kleppe, Jan Cools, PhD, Kristin Shimano, Michelle L. Hermiston, MD, PhD, Sergei Doulatov, PhD, Kolja Eppert, PhD, Elisa Laurenti, PhD, Faiyaz Notta, PhD, John E Dick, PhD, Giuseppe Basso, MD PhD, Stephen P. Hunger, MD, Mignon L Loh, MD, Meenakshi Devidas, PhD, Brent L. Wood, MD, PhD, Stuart S. Winter, MD, Kimberly Dunsmore, MD, Robert S. Fulton, MS, Lucinda A. Fulton, MS, Xin Hong, PhD, Christopher C. Harris, BS, David J. Dooling, PhD, Kerri Ochoa, Kimberly J Johnson, John C Obenauer, Ching-Hon Pui, MD, Susana C. Raimondi, PhD, Clayton W Naeve, PhD, Timothy J Ley, MD, Elaine R Mardis, PhD, Richard K Wilson, PhD, James R Downing, MD, Charles G Mullighan, MBBS, MD, FRACP, FRCPA, MSc

Blood (2011) 118 (21): 68.

https://doi.org/10.1182/blood.V118.21.68.68

Published: 2011

Journal Articles

Identification and Characterization of Human Leukemia Stem Cell Functional Regulators

Kolja Eppert, PhD, Karin G Hermans, PhD, John E. Dick, PhD

Blood (2011) 118 (21): 2955.

https://doi.org/10.1182/blood.V118.21.2955.2955

Published: 2011

Journal Articles

Lysosomal Disruption Selectively Targets Leukemia Cells and Leukemia Stem Cells Through A Mechanism Related to Increased Reactive Oxygen Species Production

Blood (2011) 118 (21): 61.

https://doi.org/10.1182/blood.V118.21.61.61

Published: 2011

Journal Articles

Enriched MicroRNA-126 Bioactivity Marks the Primitive Compartment In AML and Regulates LSC Numbers

Eric Lechman, PhD, Bernhard Gentner, MD, Hidefumi Hiramatsu, MD, Kristin J Hope, PhD, Katsuto Takenaka, MD, Kolja Eppert, PhD, Mark D. Minden, MD, PhD, Luigi Naldini, MD, PhD, John E. Dick, PhD

Blood (2010) 116 (21): 94.

https://doi.org/10.1182/blood.V116.21.94.94

Published: 2010

Journal Articles

High Levels of MicroRNA-126 Bioactivity Specify the LSC Compartment in AML

Eric R Lechman, MS, PhD, Hidefumi Hiramatsu, MD, PhD, Bernhard Gentner, MD, Kristin Hope, PhD, Katsuto Takenaka, MD, Kolja Eppert, PhD, Mark D. Minden, MD, PhD, Luigi Naldini, John E. Dick, PhD

Blood (2008) 112 (11): 510.

https://doi.org/10.1182/blood.V112.11.510.510

Published: 2008

NARROW

Single-Cell Transcriptomic Profiling of De Novo and Relapsed Acute Myeloid Leukemia Identifies a Leukemic Stemness Program Shared across Diverse Phenotypes

CD200 Is a Marker of LSC Activity in Acute Myeloid Leukemia

Identification of Existing Bioactive Compounds That Target Acute Myeloid Leukemia Stem Cells

G Protein-Coupled Receptor 56 As a Potential Regulator of Normal and Leukemic Stem Cells

Gene Expression and Mutation Analysis (GEMA) –Guided Precision Medicine Targeting PARP1 to Induce Synthetic Lethality in DNA-PK –Deficient Quiescent and BRCA-Deficient Proliferating Leukemia Stem and Progenitor Cells

Mir-126 Governs Human Leukemia Stem Cell Quiescence and Chemotherapy Resistance

Discovery of Novel Recurrent Mutations in Childhood Early T-Cell Precursor Acute Lymphoblastic Leukemia by Whole Genome Sequencing - a Report From the St Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project

Identification and Characterization of Human Leukemia Stem Cell Functional Regulators

Lysosomal Disruption Selectively Targets Leukemia Cells and Leukemia Stem Cells Through A Mechanism Related to Increased Reactive Oxygen Species Production

Enriched MicroRNA-126 Bioactivity Marks the Primitive Compartment In AML and Regulates LSC Numbers

High Levels of MicroRNA-126 Bioactivity Specify the LSC Compartment in AML

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American Society of Hematology

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American Society of Hematology

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