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Karène Mahtouk
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Journal Articles

A Comprehensive Study of the VHL -R200W Chuvash Polycythemia Mutation Reveals a Gradual Dysregulation of the Hypoxia Pathway in Oncogenesis

Betty Gardie, PhD, Sophie Couvé, PhD, Charline Ladroue, PhD, Elodie Laine, PhD, Karène Mahtouk, PhD, Justine Guégan, M.Sc., Sophie Gad, PhD, Hélène Le Jeune, B.Sc., Bernard Lecomte, MD, Jean-Christophe Pagès, MD, PhD, Patrick Benusiglio, MD PhD, Brigitte Bressac-de Paillerets, Pharm.D., PhD, Jean Feunteun, PhD, Philippe Dessen, PhD, Sylvie Hermouet, MD, PhD, Luba Tchertanov, PhD, David R. Mole, PhD, William G. Kaelin, MD, Peter J Ratcliffe, PhD, Stephane Richard, MD, PhD
Journal: Blood
Blood (2014) 124 (21): 4020.
https://doi.org/10.1182/blood.V124.21.4020.4020
Published: 2014
Journal Articles

Transcriptional Silencing of the Wnt-Antagonist Dickkopf-1 (DKK1) by Promoter Methylation Unleashes Aberrant Wnt Signaling In Advanced Multiple Myeloma

Kinga A Kocemba, MSc, Richard W Groen, PhD, Harmen van Andel, BSc, Karene Mahtouk, PhD, Marie Jose Kersten, MD, PhD, Marcel Spaargaren, PhD, Steven T Pals, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 1919.
https://doi.org/10.1182/blood.V116.21.1919.1919
Published: 2010
Journal Articles

Induction of angiogenesis by normal and malignant plasma cells

Dirk Hose, Jérôme Moreaux, Tobias Meissner, Anja Seckinger, Hartmut Goldschmidt, Axel Benner, Karène Mahtouk, Jens Hillengass, Thierry Rème, John De Vos, Michael Hundemer, Maud Condomines, Uta Bertsch, Jean-François Rossi, Anna Jauch, Bernard Klein, Thomas Möhler
Journal: Blood
Blood (2009) 114 (1): 128–143.
https://doi.org/10.1182/blood-2008-10-184226
Published: 2009
Includes: Supplemental data
Journal Articles

The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor

Anne Catherine Sprynski, Dirk Hose, Laurent Caillot, Thierry Réme, John D. Shaughnessy, Jr, Bart Barlogie, Anja Seckinger, Jérôme Moreaux, Michael Hundemer, Michel Jourdan, Tobias Meißner, Anna Jauch, Karène Mahtouk, Alboukadel Kassambara, Uta Bertsch, Jean François Rossi, Hartmut Goldschmidt, Bernard Klein
Journal: Blood
Blood (2009) 113 (19): 4614–4626.
https://doi.org/10.1182/blood-2008-07-170464
Published: 2009
Journal Articles

Binding of TACI and APRIL to Syndecan-1 Confer on Them a Major Role in Multiple Myeloma.

Jerome Moreaux, PhD, Anne-Catherine Sprynski, Karene Mahtouk, PhD, Philippe Moine, Nicolas Robert, Jean-François Rossi, MD, PhD, Bernard Klein, PhD
Journal: Blood
Blood (2007) 110 (11): 3522.
https://doi.org/10.1182/blood.V110.11.3522.3522
Published: 2007
Journal Articles

Angiogenic Signature of Multiple Myeloma Determined by Gene Expression Profiling.

Dirk Hose, Jerome Moreaux, Tobias Meissner, Jean-Francois Rossi, Axel Benner, Karene Mahtouk, Anja Seckinger, Christiane Heiss, Michael Hundemer, Thierry Reme, Jens Hillengass, Katja Herde, Uta Bertsch, John DeVos, Sabine Wenisch, Veronique Pantesco, Anna Jauch, Eric Jourdan, Hartmut Goldschmidt, Bernard Klein, Thomas Moehler
Journal: Blood
Blood (2007) 110 (11): 2484.
https://doi.org/10.1182/blood.V110.11.2484.2484
Published: 2007
Journal Articles

Heparanase influences expression and shedding of syndecan-1, and its expression by the bone marrow environment is a bad prognostic factor in multiple myeloma

Karène Mahtouk, Dirk Hose, Pierre Raynaud, Michael Hundemer, Michel Jourdan, Eric Jourdan, Veronique Pantesco, Marion Baudard, John De Vos, Marion Larroque, Thomas Moehler, Jean-Francois Rossi, Thierry Rème, Hartmut Goldschmidt, Bernard Klein
Journal: Blood
Blood (2007) 109 (11): 4914–4923.
https://doi.org/10.1182/blood-2006-08-043232
Published: 2007
Journal Articles

Heparanase Influences Expression and Shedding of Syndecan-1, and Its Expression by the Bone Marrow Environment Is a Bad Prognostic Factor in Multiple Myeloma.

Karene Mahtouk, Dirk Hose, Thierry Reme, Michael Hundemer, Michel Jourdan, Eric Jourdan, Veronique Pantesco, Marion Baudard, John De Vos, Marion Larroque, Thomas Moehler, Jean-Francois Rossi, Hartmut Goldschmidt, Bernard Klein
Journal: Blood
Blood (2006) 108 (11): 3502.
https://doi.org/10.1182/blood.V108.11.3502.3502
Published: 2006
Journal Articles

TACI and BCMA, Unlike BAFF-R, Are Expressed by Human Myeloma Cell Lines and TACI + Cell Lines Have a Gene Signature Indicative of Mature Bone Marrow Plasma Cells and Bone Marrow Environment Dependence.

Jerome Moreaux, Friedrich W. Cremer, Thierry Reme, Karene Mahtouk, Veronique Pantesco, John de Vos, Marion Moos, Nicolas Robert, Hartmut Goldschmidt, Jean-François Rossi, Dirk Hose, Bernard Klein
Journal: Blood
Blood (2005) 106 (11): 3400.
https://doi.org/10.1182/blood.V106.11.3400.3400
Published: 2005
Journal Articles

The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature

Jérôme Moreaux, Friedrich W. Cremer, Thierry Reme, Marc Raab, Karene Mahtouk, Philine Kaukel, Veronique Pantesco, John De Vos, Eric Jourdan, Anna Jauch, Eric Legouffe, Marion Moos, Genevieve Fiol, Hartmut Goldschmidt, Jean François Rossi, Dirk Hose, Bernard Klein
Journal: Blood
Blood (2005) 106 (3): 1021–1030.
https://doi.org/10.1182/blood-2004-11-4512
Published: 2005
Includes: Supplemental data