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Juliana M Benito, PhD
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Journal Articles

Bone Marrow Microenvironment Induces Stem Cell-Like Phenotype In Acute Myeloid Leukemia

Free
Venkata L Battula, Ph.D., Juliana M Benito, PhD, Anitha Somanchi, Seshagiri Duvvuri, Lauren Hodgson, Ye Chen, PhD, Wencai Ma, Ph.D., Richard E. Davis, M.D., Ian K. McNiece, PhD, Elizabeth J Shpall, MD, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2457.
https://doi.org/10.1182/blood.V122.21.2457.2457
Published: 2013
Journal Articles

Proteomic, Gene Expression, and Micro-RNA Analysis Of Bone Marrow Mesenchymal Stromal Cells In Acute Myeloid Leukemia Identifies Pro-Inflammatory, Pro-Survival Signatures In Vitro and In Vivo

Free
Michael Andreeff, MD, PhD, Rui-yu Wang, MD, PhD, Richard E. Davis, M.D., Rodrigo Jacamo, PhD, Peter P. Ruvolo, PhD, Teresa McQueen, BS, Xielin Huang, PhD, Venkata L Battula, Ph.D., Ye Chen, PhD, Shonali Majumdar, Juliana M Benito, PhD, Zhihong Zeng, MD, Christopher B. Benton, MD, Bing Z Carter, PhD, Hong Mu, MD, PhD, Wencai Ma, Ph.D., Vivian R Ruvolo, MA, Lauren Hodgson, Sergej Konoplev, MD, PhD, Rongqing Pan, MS, Anitha Somanchi, Dirk Strunck, Qiguo Zhang, Steven M. Kornblau, MD, Hagop M Kantarjian, MD, Guido Marcucci, MD, Ramiro Garzon, MD, Johannes Zuber, Scott W. Lowe, PhD, Carlo M. Croce, MD, Marina Konopleva, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3685.
https://doi.org/10.1182/blood.V122.21.3685.3685
Published: 2013
Journal Articles

Acute Lymphoblastic Leukemia Is a Bcl-2 Dependent Disease: Proteomic Profiling and Pre-Clinical Efficacy Of a Selective Bcl-2 Antagonist ABT-199

Free
Marina Konopleva, MD, PhD, Juliana M Benito, PhD, Karine G. Harutyunyan, PhD, Isabel Marzo, LaKiesha Debose, Oscar Gonzalo, Ping Zhou, Rodrigo Jacamo, PhD, Eugene Park, Markus Muschen, MD, PhD, James C. Mulloy, PhD, Linda J Bendall, BSc, PhD, Patrick A Zweidler-McKay, MD, PhD, Kevin R. Coombes, PhD, Yihua Qiu, MD, Nianxiang Zhang, PhD, Joel Leverson, PhD, Deborah A. Thomas, MD, Susan O'Brien, MD, Hagop M. Kantarjian, MD, Steven M. Kornblau, MD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3919.
https://doi.org/10.1182/blood.V122.21.3919.3919
Published: 2013
Journal Articles

A Phase 1 Study Of TH-302, An Investigational Hypoxia-Targeted Drug, In Patients With Advanced Leukemias

Free
Marina Konopleva, MD, PhD, Damian R Handisides, Mary Ann Richie, RN, Juliana M Benito, PhD, Gautam Borthakur, MD, Elias J. Jabbour, MD, Stefan H. Faderl, MD, Jorge E. Cortes, MD, Stewart Kroll, Michael Andreeff, MD, PhD, Hagop M Kantarjian, MD, Deborah A. Thomas, MD
Journal: Blood
Blood (2013) 122 (21): 3920.
https://doi.org/10.1182/blood.V122.21.3920.3920
Published: 2013
Journal Articles

BCL-2-Selective BH3 Mimetic ABT-199 Is a Potent Agent For Acute Myeloid Leukemia

Free
Rongqing Pan, MS, LaKeisha Debose, MS, Juliana M Benito, PhD, Leonard S Golfman, PhD, Patrick A Zweidler-McKay, MD, PhD, Lina Han, PhD, Karine G. Harutyunyan, PhD, Hong Mu, MD, PhD, Vivian R Ruvolo, MA, Eugene Park, Markus Muschen, MD, PhD, Joel Leverson, PhD, Gautam Borthakur, MD, Hagop M Kantarjian, MD, Peter P. Ruvolo, PhD, Michael Andreeff, MD, PhD, Marina Konopleva, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1456.
https://doi.org/10.1182/blood.V122.21.1456.1456
Published: 2013
Journal Articles

Leukemia Microenvironment and Pathologic Hypoxia: Sensitivity to Hypoxia-Activated Cytotoxin TH-302

Free
Juliana M Benito, PhD, Volgin Y Andrei, Ye Chen, PhD, Lu Hongbo, Yuexi Shi, Teresa McQueen, Patrick A Zweidler-McKay, MD, PhD, Damian R Handisides, Charles Hart, Michael Andreeff, MD, PhD, Marina Konopleva, M.D., Ph.D.
Journal: Blood
Blood (2012) 120 (21): 1523.
https://doi.org/10.1182/blood.V120.21.1523.1523
Published: 2012
Journal Articles

Targeting Hypoxia and AKR1C3 with PR104 in Patients with Acute Leukemia

Free
Juliana M Benito, PhD, Hongbo Lu, William R Wilson, PhD, Teresa J Melink, NP, MSN, Jennie Bretz, Sergej Konoplev, MD, PhD, Elihu H. Estey, MD, Hagop M. Kantarjian, MD, John C Gutheil, MD, Michael Andreeff, MD, PhD, Marina Konopleva, M.D., Ph.D.
Journal: Blood
Blood (2012) 120 (21): 3615.
https://doi.org/10.1182/blood.V120.21.3615.3615
Published: 2012
Journal Articles

Phase I/II Study of PR104, a Bioreductive Prodrug, in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML) Using Patient-Specific Adaptive Dose Selection

Free
Marina Konopleva, M.D., Ph.D., Gautam Borthakur, Peter F Thall, PhD, Andrew Coveler, MD, Farhad Ravandi, MD, Elias Jabbour, Hoang Q Nguyen, PhD, Juliana M Benito, PhD, Yongchuan Gu, PhD, William R Wilson, PhD, Teresa J Melink, NP, MSN, Hagop M. Kantarjian, John C Gutheil, MD, Elihu H Estey, MD
Journal: Blood
Blood (2011) 118 (21): 1523.
https://doi.org/10.1182/blood.V118.21.1523.1523
Published: 2011