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Juan Carlos Zúñiga-Pflücker
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Journal Articles

Navigating Lineage Options: A Data-Driven Quest to Uncover T Cell Fate Decision Trajectories

Vinothkumar Rajan, Christina R Lee, Juan Carlos Zuniga-pflucker
Journal: Blood
Blood (2024) 144 (Supplement 1): 3921.
https://doi.org/10.1182/blood-2024-208184
Published: 2024
Journal Articles

Modeling altered T-cell development with induced pluripotent stem cells from patients with RAG1 -dependent immune deficiencies

Patrick M. Brauer, Itai M. Pessach, Erik Clarke, Jared H. Rowe, Lisa Ott de Bruin, Yu Nee Lee, Carmen Dominguez-Brauer, Anne M. Comeau, Geneve Awong, Kerstin Felgentreff, Yuhang H. Zhang, Andrea Bredemeyer, Waleed Al-Herz, Likun Du, Francesca Ververs, Marion Kennedy, Silvia Giliani, Gordon Keller, Barry P. Sleckman, David G. Schatz, Frederic D. Bushman, Luigi D. Notarangelo, Juan Carlos Zúñiga-Pflücker
Journal: Blood
Blood (2016) 128 (6): 783–793.
https://doi.org/10.1182/blood-2015-10-676304
Published: 2016
Includes: Supplemental data
Journal Articles

Notch signals are required for in vitro but not in vivo maintenance of human hematopoietic stem cells and delay the appearance of multipotent progenitors

Patricia Benveniste, Pablo Serra, Dzana Dervovic, Elaine Herer, Gisele Knowles, Mahmood Mohtashami, Juan Carlos Zúñiga-Pflücker
Journal: Blood
Blood (2014) 123 (8): 1167–1177.
https://doi.org/10.1182/blood-2013-07-505099
Published: 2014
Includes: Supplemental data
Journal Articles

Human proT-cells generated in vitro facilitate hematopoietic stem cell-derived T-lymphopoiesis in vivo and restore thymic architecture

Génève Awong, Jastaranpreet Singh, Mahmood Mohtashami, Maria Malm, Ross N. La Motte-Mohs, Patricia M. Benveniste, Pablo Serra, Elaine Herer, Marcel R. van den Brink, Juan Carlos Zúñiga-Pflücker
Journal: Blood
Blood (2013) 122 (26): 4210–4219.
https://doi.org/10.1182/blood-2012-12-472803
Published: 2013
Includes: Supplemental data
Journal Articles

HES1 opposes a PTEN-dependent check on survival, differentiation, and proliferation of TCRβ-selected mouse thymocytes

Gladys W. Wong, Gisele C. Knowles, Tak W. Mak, Adolfo A. Ferrando, Juan Carlos Zúñiga-Pflücker
Journal: Blood
Blood (2012) 120 (7): 1439–1448.
https://doi.org/10.1182/blood-2011-12-395319
Published: 2012
Includes: Supplemental data
Journal Articles

gp96, an endoplasmic reticulum master chaperone for integrins and Toll-like receptors, selectively regulates early T and B lymphopoiesis

Matthew Staron, Yi Yang, Bei Liu, Janet Li, Yuankai Shen, Juan Carlos Zúñiga-Pflücker, Hector L. Aguila, Irving Goldschneider, Zihai Li
Journal: Blood
Blood (2010) 115 (12): 2380–2390.
https://doi.org/10.1182/blood-2009-07-233031
Published: 2010
Includes: Supplemental data
Journal Articles

Characterization in vitro and engraftment potential in vivo of human progenitor T cells generated from hematopoietic stem cells

Génève Awong, Elaine Herer, Charles D. Surh, John E. Dick, Ross N. La Motte-Mohs, Juan Carlos Zúñiga-Pflücker
Journal: Blood
Blood (2009) 114 (5): 972–982.
https://doi.org/10.1182/blood-2008-10-187013
Published: 2009
Includes: Supplemental data
Journal Articles

Differences in lymphocyte developmental potential between human embryonic stem cell and umbilical cord blood–derived hematopoietic progenitor cells

Colin H. Martin, Petter S. Woll, Zhenya Ni, Juan Carlos Zúñiga-Pflücker, Dan S. Kaufman
Journal: Blood
Blood (2008) 112 (7): 2730–2737.
https://doi.org/10.1182/blood-2008-01-133801
Published: 2008
Journal Articles

Targeted ‘Off-the-Shelf’ Tumor Immunotherapy Using Allogeneic T-Cell Precursors.

Johannes L. Zakrzewski, MD, David Suh, Odette M. Smith, Christopher King, Gabrielle L. Goldberg, PhD, Robert Jenq, MD, Amanda M. Holland, Jeremy Grubin, Sydney X. Lu, Javier Cabrera-Perez, Gabrielle Rizzuto, Derek B. Sant’Angelo, PhD, Marcel R.M. van den Brink, MD, PhD, John C. Markley, Isabelle Riviere, PhD, Michel Sadelain, MD, PhD, Juan Carlos Zuniga-Pflucker, PhD
Journal: Blood
Blood (2007) 110 (11): 579.
https://doi.org/10.1182/blood.V110.11.579.579
Published: 2007
Journal Articles

Adoptive Transfer of In Vitro Generated T Cell Precursors Enhances Donor T Cell Reconstitution and Graft-Versus-Tumor Activity in Allogeneic Hematopoietic Stem Cell Transplantation Recipients.

Johannes L. Zakrzewski, MD, Adam A. Kochman, Sidney X. Lu, Theis H. Terwey, MD, Theo D. Kim, MD, Vanessa M. Hubbard, Stephanie J. Muriglan, David Suh, Javier Cabrera-Perez, Radhika Radhakrishnan, Glenn Heller, PhD, Juan Carlos Zuniga-Pflucker, PhD, Onder Alpdogan, MD, Marcel R.M. van den Brink, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 63.
https://doi.org/10.1182/blood.V106.11.63.63
Published: 2005