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Journal Articles

RNA Sequencing of Hodgkin Lymphoma Reed-Sternberg Cells Uncovers a Plasma Cell Signature and Escape from NK Cell Recognition

Ethel Cesarman, MD PhD, Mikhail Roshal, MD PhD, Jonathan Reichel, PhD, Wagner Florian, PhD, Bhavneet Binder, Sakellarios Zairis, Jouliana Sadek, PhD, Joshua Brody, MD, Raul Rabadan, PhD, Sandeep Dave, MD

Blood (2019) 134 (Supplement_1): 549.

https://doi.org/10.1182/blood-2019-131163

Published: 2019

Journal Articles

Engine: Phase III Randomized Study of Enzastaurin/R-CHOP Versus Placebo/R-CHOP in Frontline High Risk Diffuse Large B Cell Lymphoma Patients with Novel Genomic Biomarker DGM1

Jun Zhu, MD PhD, Grzegorz Nowakowski, MD, Qingyuan Zhang, Joshua Brody, MD, Xiuhua Sun, MD, Joseph Maly, MD, Yuqin Song, MD PhD, Yongping Song, MD PhD, Jennifer Kimberly Lue, MD, Wen Luo, PhD, Lei Zhang, MD, Isabel Han, Manoj Jivani, Young Liu, Ling Li, MD, Joan Sun, MBA, Stephen D. Smith, MD

Blood (2019) 134 (Supplement_1): 5330.

https://doi.org/10.1182/blood-2019-124930

Published: 2019

Journal Articles

Constitutive Phosphorylation of CYLD Promotes ATLL Survival By Inhibiting RIPK1-Dependent Cell Death

Xin Xu, Matko Kalac, MDPhD, Michael Markson, Joshua Brody, MD, Govind Bhagat, Feng Liu, Qingshan Li, Adrian Ting, PhD

Blood (2018) 132 (Supplement 1): 1581.

https://doi.org/10.1182/blood-2018-99-117397

Published: 2018

Journal Articles

Safety and Efficacy of the Combination of Ibrutinib and Nivolumab in Patients with Relapsed Non-Hodgkin Lymphoma or Chronic Lymphocytic Leukemia

Blood (2017) 130 (Supplement 1): 833.

https://doi.org/10.1182/blood.V130.Suppl_1.833.833

Published: 2017

Journal Articles

In Situ Vaccination Improves Efficacy of PD-1 Blockade in Unresponsive Lymphoma Tumors through Induction of a Highly Efficient Cross-Presenting Dendritic Cell Subset Expressing TLR3

Linda Hammerich, Maxime Dhainaut, Tibor Keler, Thomas Davis, MD, Andres M Salazar, Brian D Brown, Joshua Brody, MD

Blood (2017) 130 (Supplement 1): 4106.

https://doi.org/10.1182/blood.V130.Suppl_1.4106.4106

Published: 2017

Journal Articles

Combining In Situ Vaccination with Immune Checkpoint Blockade Induces Long-Term Regression of Lymphoma Tumors

Linda Hammerich, PhD, Thomas A. Davis, MD, Tibor Keler, PhD, Andres M Salazar, Joshua Brody, MD

Blood (2016) 128 (22): 465.

https://doi.org/10.1182/blood.V128.22.465.465

Published: 2016

Journal Articles

Natural Toll-like Receptor Agonists for in Situ Vaccination Lymphoma Immunotherapy

Paul Peng, PhD, Joshua Brody, MD, Linda Hammerich, PhD

Blood (2015) 126 (23): 4002.

https://doi.org/10.1182/blood.V126.23.4002.4002

Published: 2015

Journal Articles

Phase I/II Clinical Trial of CpG-Activated Whole Cell Vaccine in Mantle Cell Lymphoma (MCL): Results in Safety and Efficacy from Planned Interim Analysis

Blood (2015) 126 (23): 1536.

https://doi.org/10.1182/blood.V126.23.1536.1536

Published: 2015

Journal Articles

Dose-Escalated, Intratumoral TLR9 Agonist and Low-Dose Radiation Induce Abscopal Effects in Follicular Lymphoma

Holbrook E Kohrt, MD PhD, Jaqueline Chu, MD, Joshua Brody, MD, Debra K Czerwinski, Cariad Chester, Mohith Sadaram, BS, Ranjana Advani, MD, Youn H. Kim, MD, Richard T. Hoppe, MD, Susan J. Knox, MD PhD, Irene Wapnir, MD, Robert J. Tibshirani, PhD, Ron Levy, MD

Blood (2014) 124 (21): 3092.

https://doi.org/10.1182/blood.V124.21.3092.3092

Published: 2014

Journal Articles

Turning a Tumor into a Vaccine Factory: In Situ Vaccination for Low-Grade Lymphoma

Thomas Marron, MD PhD, Nina Bhardwaj, MD PhD, Elizabeth Crowley, Tibor Keler, PhD, Thomas A. Davis, MD, Joshua Brody, MD

Blood (2014) 124 (21): 5473.

https://doi.org/10.1182/blood.V124.21.5473.5473

Published: 2014

Journal Articles

High-Resolution Genomic Methylation Analysis Using Next Generation Sequencing Identifies Loci Associated With Differential Prognosis In Mantle Cell Lymphoma Patients Treated With Bortezomib + DA-EPOCH-R

Violetta V. Leshchenko, PhD, Pei-Yu Kuo, MS, Deepak Perumal, PhD, Melissa J Fazzari, PhD, Francine E. Garrett-Bakelman, MD, PhD, Nakhle S Saba, MD, Delong Liu, PhD, Weijia Zhang, PhD, Joshua Brody, MD, Ari M. Melnick, MD, Kieron Dunleavy, MD, Wyndham H Wilson, MD, PhD, Adrian Wiestner, MD, PhD, Samir Parekh, MD

Blood (2013) 122 (21): 3760.

https://doi.org/10.1182/blood.V122.21.3760.3760

Published: 2013

Journal Articles

High-Throughput Sequencing Of T Cell Receptors Detects Signatures Of T Cell Repertoire That Predict MRD Status In Patients With Mantle Cell Lymphoma Undergoing Immunotransplantation

Malek Faham, MD, PhD, Joshua Brody, MD, Holbrook E Kohrt, MD, PhD, Debra K Czerwinski, Ronald Levy, MD

Blood (2013) 122 (21): 4251.

https://doi.org/10.1182/blood.V122.21.4251.4251

Published: 2013

Journal Articles

Potentiated B-Cell Antigen Receptor Signaling In Mantle Cell Lymphoma Is Associated With Overexpression Of Surface CD79B and IgM

June Helen Myklebust, PhD, Joshua Brody, MD, Ash A. Alizadeh, MD, PhD, Debra K Czerwinski, Arne Kolstad, MD, PhD, Michael R Green, Ph.D., Roch Houot, MD, PhD, Jan Delabie, MD, PhD, Holbrook E Kohrt, MD, PhD, Jonathan M. Irish, PhD, Ronald Levy, MD

Blood (2013) 122 (21): 1768.

https://doi.org/10.1182/blood.V122.21.1768.1768

Published: 2013

Journal Articles

Immunotransplant Expands Vaccine-Induced Memory T Cell Responses In Patients With Mantle Cell Lymphoma

Debra K Czerwinski, Joshua Brody, MD, Holbrook E Kohrt, MD, PhD, Malek Faham, MD, PhD, Etelka Gabriel, Robert Negrin, MD, Ronald Levy, MD

Blood (2013) 122 (21): 1816.

https://doi.org/10.1182/blood.V122.21.1816.1816

Published: 2013

Journal Articles

Local Treg Immunomodulation Cures Metastatic Lymphoma Including CNS Sites

Aurelien Marabelle, M.D., MSc, Holbrook E Kohrt, MD, Joshua Brody, MD, James Anthony Torchia, Gang Zhou, Richard Luong, BVSc, DACVP, Ranjani Rajapaksa, PhD, Victor Tse, M.D., PhD, Ronald Levy, MD

Blood (2011) 118 (21): LBA-2.

https://doi.org/10.1182/blood.V118.21.LBA-2.LBA-2

Published: 2011

Journal Articles

NF-κB Signaling In Response to CpG Stratifies Mantle Cell Lymphoma Patient Outcome

June Helen Myklebust, PhD, Jonathan Michael Irish, PhD, Joshua Brody, MD, Ash A. Alizadeh, MD/PhD, Debra Czerwinski, Roch Houot, MD, PhD, Holbrook E Kohrt, MD, Arne Kolstad, MD, PhD, Ronald Levy, MD

Blood (2010) 116 (21): 144.

https://doi.org/10.1182/blood.V116.21.144.144

Published: 2010

Journal Articles

In Situ Vaccination with TLR9 Agonist Combined with Local Radiation In Mycosis Fungoides: Analysis of Phase I/II Study

Youn H. Kim, MD, Dita Gratzinger, MD, PhD, Cameron Harrison, MD, Joshua Brody, MD, Debra Czerwinski, Leon Xing, Anjali Morales, MD, PhD, Weiyun Ai, MD, PhD, Farah Abdulla, MD, Daniel Navi, MD, Robert J. Tibshirani, PhD, Ranjana Advani, MD, Yasodha Natkunam, MD, PhD, Richard T. Hoppe, MD, Ron Levy, MD

Blood (2010) 116 (21): 286.

https://doi.org/10.1182/blood.V116.21.286.286

Published: 2010

Journal Articles

Adoptive Therapy for Lymphoma with CD4 Memory T Cells Depleted of CD137-Expressing Tregs.

Matthew J Goldstein, Roch Houot, MD, Holbrook E Kohrt, MD, Joshua Brody, MD, Ronald Levy, MD

Blood (2009) 114 (22): 1693.

https://doi.org/10.1182/blood.V114.22.1693.1693

Published: 2009

Journal Articles

A Subpopulation of Follicular Lymphoma Tumor Infiltrating T Cells Shows Suppressed Common Gamma Chain Cytokine Signaling.

June H Myklebust, PhD, Jonathan M Irish, PhD, Roch Houot, MD, Joshua Brody, MD, Debra K Czerwinski, Ash A Alizadeh, MD, PhD, Arne Kolstad, MD, PhD, Ronald Levy, MD

Blood (2009) 114 (22): 759.

https://doi.org/10.1182/blood.V114.22.759.759

Published: 2009

Journal Articles

Adoptive Cell Therapy for Lymphoma: Use of CpG-Loaded Tumor Cells to Generate Potent Anti-Tumor CD4 T Cell Immunity.

Matthew J Goldstein, Bindu Varghese, PhD, Ranjani Rajapaksa, PhD, Joshua Brody, MD, Shoshana Levy, PhD, Ronald Levy, MD

Blood (2009) 114 (22): 929.

https://doi.org/10.1182/blood.V114.22.929.929

Published: 2009

NARROW

RNA Sequencing of Hodgkin Lymphoma Reed-Sternberg Cells Uncovers a Plasma Cell Signature and Escape from NK Cell Recognition

Engine: Phase III Randomized Study of Enzastaurin/R-CHOP Versus Placebo/R-CHOP in Frontline High Risk Diffuse Large B Cell Lymphoma Patients with Novel Genomic Biomarker DGM1

Constitutive Phosphorylation of CYLD Promotes ATLL Survival By Inhibiting RIPK1-Dependent Cell Death

Safety and Efficacy of the Combination of Ibrutinib and Nivolumab in Patients with Relapsed Non-Hodgkin Lymphoma or Chronic Lymphocytic Leukemia

In Situ Vaccination Improves Efficacy of PD-1 Blockade in Unresponsive Lymphoma Tumors through Induction of a Highly Efficient Cross-Presenting Dendritic Cell Subset Expressing TLR3

Combining In Situ Vaccination with Immune Checkpoint Blockade Induces Long-Term Regression of Lymphoma Tumors

Natural Toll-like Receptor Agonists for in Situ Vaccination Lymphoma Immunotherapy

Phase I/II Clinical Trial of CpG-Activated Whole Cell Vaccine in Mantle Cell Lymphoma (MCL): Results in Safety and Efficacy from Planned Interim Analysis

Dose-Escalated, Intratumoral TLR9 Agonist and Low-Dose Radiation Induce Abscopal Effects in Follicular Lymphoma

Turning a Tumor into a Vaccine Factory: In Situ Vaccination for Low-Grade Lymphoma

High-Resolution Genomic Methylation Analysis Using Next Generation Sequencing Identifies Loci Associated With Differential Prognosis In Mantle Cell Lymphoma Patients Treated With Bortezomib + DA-EPOCH-R

High-Throughput Sequencing Of T Cell Receptors Detects Signatures Of T Cell Repertoire That Predict MRD Status In Patients With Mantle Cell Lymphoma Undergoing Immunotransplantation

Potentiated B-Cell Antigen Receptor Signaling In Mantle Cell Lymphoma Is Associated With Overexpression Of Surface CD79B and IgM

Immunotransplant Expands Vaccine-Induced Memory T Cell Responses In Patients With Mantle Cell Lymphoma

Local Treg Immunomodulation Cures Metastatic Lymphoma Including CNS Sites

NF-κB Signaling In Response to CpG Stratifies Mantle Cell Lymphoma Patient Outcome

In Situ Vaccination with TLR9 Agonist Combined with Local Radiation In Mycosis Fungoides: Analysis of Phase I/II Study

Adoptive Therapy for Lymphoma with CD4 Memory T Cells Depleted of CD137-Expressing Tregs.

A Subpopulation of Follicular Lymphoma Tumor Infiltrating T Cells Shows Suppressed Common Gamma Chain Cytokine Signaling.

Adoptive Cell Therapy for Lymphoma: Use of CpG-Loaded Tumor Cells to Generate Potent Anti-Tumor CD4 T Cell Immunity.

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American Society of Hematology

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American Society of Hematology

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