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Joseph E. Saavedra
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Journal Articles

JS-K, a GST-activated nitric oxide generator, induces DNA double-strand breaks, activates DNA damage response pathways, and induces apoptosis in vitro and in vivo in human multiple myeloma cells

Tanyel Kiziltepe, Teru Hideshima, Kenji Ishitsuka, Enrique M. Ocio, Noopur Raje, Laurence Catley, Chun-Qi Li, Laura J. Trudel, Hiroshi Yasui, Sonia Vallet, Jeffery L. Kutok, Dharminder Chauhan, Constantine S. Mitsiades, Joseph E. Saavedra, Gerald N. Wogan, Larry K. Keefer, Paul J. Shami, Kenneth C. Anderson
Journal: Blood
Blood (2007) 110 (2): 709–718.
https://doi.org/10.1182/blood-2006-10-052845
Published: 2007
Includes: Supplemental data
Journal Articles

JS-K, a GST-Activated Nitric Oxide Generator, Induces DNA-Double Strand Breaks and Inhibits Growth and Survival of Multiple Myeloma Cells In Vitro and In Vivo .

Tanyel Kiziltepe, PhD, Teru Hideshima, Noopur Raje, Kenji Ishitsuka, Enrique M. Ocio, Laurence Catley, Chun-Qi Li, Laura Trudel, Hiroshi Yasui, Norihiko Shirashi, Yu-Tzu Tai, Dharminder Chauhan, Constantine Mitsiades, Joseph E. Saavedra, Gerald N. Wogan, Larry K. Keefer, Paul J. Shami, Kenneth C. Anderson
Journal: Blood
Blood (2006) 108 (11): 3453.
https://doi.org/10.1182/blood.V108.11.3453.3453
Published: 2006
Journal Articles

Synergy Studies between the Nitric Oxide (NO) Donor JS-K and Other Anti-Leukemic Agents.

Paul J. Shami, MD, Jordan K. Eddington, Vidya Udupi, PhD, Ken M. Kosak, MS, Joseph E. Saavedra, PhD, Larry K. Keefer, PhD
Journal: Blood
Blood (2006) 108 (11): 4396.
https://doi.org/10.1182/blood.V108.11.4396.4396
Published: 2006
Journal Articles

JS-K, a GST-Activated Nitric Oxide Generator, Induces Apoptosis and Overcomes In Vitro Drug Resistance in Multiple Myeloma Cells.

Tanyel Kiziltepe, PhD, Kenji Ishitsuka, MD, PhD, Teru Hideshima, MD, PhD, Noopur Raje, MD, Norihiko Shiraishi, PhD, Hiroshi Yasui, MD, PhD, Laurence Catley, MD, Dharminder Chauhan, PhD, Joseph E. Saavedra, PhD, Larry K. Keefer, PhD, Paul J. Shami, MD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2005) 106 (11): 1593.
https://doi.org/10.1182/blood.V106.11.1593.1593
Published: 2005
Journal Articles

JS-K, a Novel Nitric Oxide (NO) Generator, Shows Potent Anti-Angiogenic Activity.

Paul J. Shami, MD, Gurmeet Kaur, MS, Jagadambal Thillainathan, MS, Lee Jia, PhD, Joseph E. Saavedra, PhD, Larry K. Keefer, PhD
Journal: Blood
Blood (2004) 104 (11): 3414.
https://doi.org/10.1182/blood.V104.11.3414.3414
Published: 2004
Journal Articles

JS-K, a Novel Nitric Oxide (NO) Generator, Induces Cytochrome c Release and Caspase Activation in HL-60 Myeloid Leukemia Cells.

Paul J. Shami, MD, Vidya Udupi, PhD, Margaret Yu, MD, Swati Malaviya, MS, Joseph E. Saavedra, PhD, Larry K. Keefer, PhD
Journal: Blood
Blood (2004) 104 (11): 3415.
https://doi.org/10.1182/blood.V104.11.3415.3415
Published: 2004