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Journal Articles

A Favorable BCL-2 Family Expression Profile May Explain the Increased Susceptibility of the t(11;14) Multiple Myeloma Subgroup to Single Agent Venetoclax

Jenny Wu, Jeremy Ross, Franklin V. Peale, Jr., John D Shaughnessy, Jr., PhD, Ryan K Van Laar, PhD, Gareth J Morgan, MD PhD, Jeffrey M Venstrom, Elizabeth A. Punnoose, PhD

Blood (2016) 128 (22): 5613.

https://doi.org/10.1182/blood.V128.22.5613.5613

Published: 2016

Journal Articles

Mutation Burden in Multiple Myeloma Is Captured By Gene Expression Profiles

John D Shaughnessy, Jr., PhD, Samir Parekh, MD, Hearn Jay Cho, MD PhD, Alessandro Lagana, PhD, Ajai Chari, MD, Ryan van Laar, PhD, Sundar Jagannath, MD, Bart Barlogie, MD PhD

Blood (2016) 128 (22): 4450.

https://doi.org/10.1182/blood.V128.22.4450.4450

Published: 2016

Journal Articles

Cereblon Expression Predicts Response, Progression Free and Overall Survival After Pomalidomide and Dexamethasone Therapy in Multiple Myeloma

Blood (2012) 120 (21): 194.

https://doi.org/10.1182/blood.V120.21.194.194

Published: 2012

Journal Articles

Gene Expression Profiling (GEP) in MGUS and AMM: Predictors of Progression.

Sarah Waheed, MD, Christoph Heuck, MD, Pingping Qu, PhD, Frits van Rhee, MD, PhD, Saad Z Usmani, MD FACP, Qing Zhang, PhD, Rachael Sexton, John Crowley, PhD, Joshua Epstein, DSc, Madhav V. Dhodapkar, MD, John D Shaughnessy, Jr., PhD, Bart Barlogie, MD, PhD

Blood (2012) 120 (21): 2933.

https://doi.org/10.1182/blood.V120.21.2933.2933

Published: 2012

Journal Articles

Molecularly Classified High Risk Myeloma Cells with Low ROS Levels and High Nestin Expression Have High Proliferation Index and GEP80 Score,

Sarah K. Johnson, PhD, Yiming Zhou, PhD, Bart Barlogie, MD, Ph.D, John D Shaughnessy, Jr., PhD

Blood (2011) 118 (21): 3953.

https://doi.org/10.1182/blood.V118.21.3953.3953

Published: 2011

Journal Articles

SWOG S0120 Observational Trial for MGUS and Asymptomatic Multiple Myeloma (AMM): Imaging Predictors of Progression for Patients Treated At UAMS,

Christoph Heuck, MD, Rachael Sexton, Madhav Dhodapkar, MD, MBBS, Qing Zhang, PhD, Saad Usmani, MD, FACP, Bijay Nair, MD, Frits van Rhee, MD, PhD, Antje Hoering, PhD, John Crowley, PhD, John D Shaughnessy, Jr., PhD, Robert Z. Orlowski, MD, PhD, Bart Barlogie, MD, PhD

Blood (2011) 118 (21): 3955.

https://doi.org/10.1182/blood.V118.21.3955.3955

Published: 2011

Journal Articles

Thrombin-Induced PARI Signaling Pathway Modulates ß-Catenin in the Transformation of Symptomatic Myeloma Cells Into the Quiescent Phenotype,

Erming Tian, PhD, Saad Usmani, MD, FACP, Yiming Zhou, PhD, Bart Barlogie, MD, Ph.D, John D Shaughnessy, Jr., PhD

Blood (2011) 118 (21): 3932.

https://doi.org/10.1182/blood.V118.21.3932.3932

Published: 2011

Journal Articles

Deregulated Cellular Iron Metabolism Factors Mediate Iron Overload in Myeloma Cells and Osteoclasts, and Promote Myeloma Growth and Bone Disease,

Rakesh Bam, Wen Ling, MS, Sharmin Khan, MS, Sathisha Upparahalli Venkateshaiah, PhD, Xin Li, PhD, Frits van Rhee, MD, PhD, Bijay Nair, MD, Saad Usmani, MD, FACP, Bart Barlogie, MD, PhD, John D Shaughnessy, Jr., PhD, Joshua Epstein, DSc, Elias J. Anaissie, MD, Shmuel Yaccoby, PhD

Blood (2011) 118 (21): 3941.

https://doi.org/10.1182/blood.V118.21.3941.3941

Published: 2011

Journal Articles

Inducible Heme Oxygenase 1 (HMOX1) Promotes Osteoblastogenesis, and Inhibits Osteoclastogenesis and Myeloma-Induced Bone Disease

Xin Li, PhD, Sarah K. Johnson, PhD, Wen Ling, MS, Sharmin Khan, MS, Linda Saint John, Bart Barlogie, MD, PhD, John D Shaughnessy, Jr., PhD, Shmuel Yaccoby, PhD

Blood (2011) 118 (21): 627.

https://doi.org/10.1182/blood.V118.21.627.627

Published: 2011

Journal Articles

Prediction of Cytogenetic Abnormalities in Multiple Myeloma Based on Gene Expression Profiles

Yiming Zhou, PhD, Qing Zhang, PhD, Christoph Heuck, MD, Owen Stephens, Erming Tian, PhD, Jeffrey Sawyer, PhD, Marie-Astrid Cartron-Mizeracki, MS, Bart Barlogie, MD, PhD, John D Shaughnessy, Jr., PhD

Blood (2011) 118 (21): 629.

https://doi.org/10.1182/blood.V118.21.629.629

Published: 2011

Journal Articles

Cell Surface CXCR4 and BTK Expression Are Associated in Myeloma Cells and Osteoclast Precursors and Mediate Myeloma Cell Homing and Clonogenicity, and Osteoclastogenesis

Rakesh Bam, Wen Ling, Sharmin Khan, Angela Pennisi, MD, Sathisha Upparahalli Venkateshaiah, PhD, Xin Li, PhD, Ryan Williams, Frits van Rhee, MD, PhD, Bijay Nair, MD, Saad Usmani, MD, FACP, Bart Barlogie, MD, PhD, John D Shaughnessy, Jr., PhD, Joshua Epstein, DSc, Shmuel Yaccoby, PhD

Blood (2011) 118 (21): 884.

https://doi.org/10.1182/blood.V118.21.884.884

Published: 2011

Journal Articles

NAMPT/PBEF Enzymatic Activity Is Indispensable for Myeloma Cell Growth and Osteoclast Activity

Sathisha Upparahalli Venkateshaiah, PhD, Sharmin Khan, MS, Wen Ling, MS, Rakesh Bam, Xin Li, PhD, Bart Barlogie, MD, PhD, John D Shaughnessy, Jr., PhD, Shmuel Yaccoby, PhD

Blood (2011) 118 (21): 886.

https://doi.org/10.1182/blood.V118.21.886.886

Published: 2011

Journal Articles

Secreted Frizzled-Related Protein-3 (sFRP3) Is Produced by Myeloma Cells and Augments Wnt3a-Induced Differentiation of Mesenchymal Stem Cells and OPG Production in Osteoblasts

Ya-Wei Qiang, MD, PhD, Yu Chen, Bo Hu, PhD, Wei Qiang, MD, Christoph Heuck, MD, Shmuel Yaccoby, PhD, Joshua Epstein, DSc, Bart Barlogie, MD, PhD, John D Shaughnessy, Jr., PhD

Blood (2011) 118 (21): 808.

https://doi.org/10.1182/blood.V118.21.808.808

Published: 2011

Journal Articles

Low Expression of Nuclear Glucocorticoid Receptor Gene NR3C1 in Newly Diagnosed Myeloma Correlates with Inferior Prognosis and Is Rescued by Thalidomide

Christoph Heuck, MD, Jackie Szymonifka, Qing Zhang, PhD, Saad Usmani, MD, FACP, Bijay Nair, MD, Sarah Waheed, MD, Yazan Alsayed, MD, Frits van Rhee, MD, PhD, Elias J. Anaissie, MD, Antje Hoering, PhD, John Crowley, PhD, John D Shaughnessy, Jr., PhD, Bart Barlogie, MD, PhD

Blood (2011) 118 (21): 988.

https://doi.org/10.1182/blood.V118.21.988.988

Published: 2011

Journal Articles

Jumping Translocations 1q12 Contribute to Copy Number (CN) Alterations in Multiple Myeloma (MM): Unexpected Focal Amplifications of Receptor Chromosomes (RC)

Jeffrey Sawyer, Erming Tian, PhD, John D. Shaughnessy, Jr., PhD, Janet Lukacs, Regina Lichti Binz, Edward Thomas, Gael Sammartino, Charles Swanson, Christoph Heuck, MD, Yazan Alsayed, MD, Elias J. Anaissie, MD, Bijay Nair, MD, Sarah Waheed, MD, Saad Usmani, MD, FACP, Frits van Rhee, MD, PhD, Bart Barlogie, MD, Ph.D

Blood (2011) 118 (21): 298.

https://doi.org/10.1182/blood.V118.21.298.298

Published: 2011

Journal Articles

Bortezomib Induces Activation of b-Catenin/TCF Signaling Pathway in Multiple Myeloma

Ya-Wei Qiang, MD. PhD, Bo Hu, PhD, Yu Chen, Wei Qiang, MD, Christoph Heuck, MD, Bart Barlogie, MD, PhD, John D Shaughnessy, Jr., PhD

Blood (2011) 118 (21): 1851.

https://doi.org/10.1182/blood.V118.21.1851.1851

Published: 2011

Journal Articles

Loss of CYR61 in Myeloma Microenvironment Is Associated with Poor Survival

Sarah K. Johnson, PhD, Peter Stewart, PhD, Shmuel Yaccoby, PhD, Fenghuang Zhan, MD, PhD, Bart Barlogie, MD, Ph.D, John D Shaughnessy, Jr., PhD

Blood (2011) 118 (21): 1813.

https://doi.org/10.1182/blood.V118.21.1813.1813

Published: 2011

Journal Articles

Gene Expression Profiling (GEP) Analysis of Plasma Cells (PC) Obtained From MRI-Defined Focal Lesions (FL) Under CT-Guided Fine-Needle Aspiration Provides Better Risk Stratification in Patients with Multiple Myeloma

Qing Zhang, PhD, Pingping Qu, PhD, Emily Hansen, MS, Christoph Heuck, MD, Saad Usmani, MD, FACP, Bijay Nair, MD, Sarah Waheed, MD, Yazan Alsayed, MD, Antje Hoering, PhD, John Crowley, PhD, John D Shaughnessy, Jr., PhD, Bart Barlogie, MD, PhD

Blood (2011) 118 (21): 2896.

https://doi.org/10.1182/blood.V118.21.2896.2896

Published: 2011

Journal Articles

Gene Expression Profiling Distinguishes Waldenstrom's Macroglobulinemia Patients Presenting with Familial Disease, Advanced IPSS Prognostic Score, and Previous Treatment with Rituximab.

Zachary Hunter, Evdoxia Hatjiharissi, MD, Jenny Sun, MD, Yang Cao, Hsiuyi Tseng, Megan Lewicki, Lian Xu, Guang Yang, PhD, Yangsheng Zhou, MD, PhD, Xia Liu, Ping Gong, Christina Hanzis, Thea Ioakimidis, MS, Christopher J Patterson, Patricia Sheehy, NP, Bart Barlogie, MD, PhD, John D Shaughnessy, Jr, PhD, Steven Treon, MD, PhD

Blood (2009) 114 (22): 3930.

https://doi.org/10.1182/blood.V114.22.3930.3930

Published: 2009

Journal Articles

Adoptively Transferred Expanded Natural Killer Cells Inhibit Myeloma Tumor Growth In Vivo .

Tarun K. Garg, PhD, Susann Szmania, BS, Paul Malbrough, BS, Charles Ekworomadu, MS, Katie Stone, BS, Amberly Moreno-Bost, BS, Emily Woods, BS, Jumei Shi, MD, PhD, Shmuel Yaccoby, PhD, John D Shaughnessy, Jr., PhD, Bart Barlogie, MD, PhD, Dario Campana, MD, PhD, Frits van Rhee, MD, PhD

Blood (2009) 114 (22): 953.

https://doi.org/10.1182/blood.V114.22.953.953

Published: 2009

NARROW

A Favorable BCL-2 Family Expression Profile May Explain the Increased Susceptibility of the t(11;14) Multiple Myeloma Subgroup to Single Agent Venetoclax

Mutation Burden in Multiple Myeloma Is Captured By Gene Expression Profiles

Cereblon Expression Predicts Response, Progression Free and Overall Survival After Pomalidomide and Dexamethasone Therapy in Multiple Myeloma

Gene Expression Profiling (GEP) in MGUS and AMM: Predictors of Progression.

Molecularly Classified High Risk Myeloma Cells with Low ROS Levels and High Nestin Expression Have High Proliferation Index and GEP80 Score,

SWOG S0120 Observational Trial for MGUS and Asymptomatic Multiple Myeloma (AMM): Imaging Predictors of Progression for Patients Treated At UAMS,

Thrombin-Induced PARI Signaling Pathway Modulates ß-Catenin in the Transformation of Symptomatic Myeloma Cells Into the Quiescent Phenotype,

Deregulated Cellular Iron Metabolism Factors Mediate Iron Overload in Myeloma Cells and Osteoclasts, and Promote Myeloma Growth and Bone Disease,

Inducible Heme Oxygenase 1 (HMOX1) Promotes Osteoblastogenesis, and Inhibits Osteoclastogenesis and Myeloma-Induced Bone Disease

Prediction of Cytogenetic Abnormalities in Multiple Myeloma Based on Gene Expression Profiles

Cell Surface CXCR4 and BTK Expression Are Associated in Myeloma Cells and Osteoclast Precursors and Mediate Myeloma Cell Homing and Clonogenicity, and Osteoclastogenesis

NAMPT/PBEF Enzymatic Activity Is Indispensable for Myeloma Cell Growth and Osteoclast Activity

Secreted Frizzled-Related Protein-3 (sFRP3) Is Produced by Myeloma Cells and Augments Wnt3a-Induced Differentiation of Mesenchymal Stem Cells and OPG Production in Osteoblasts

Low Expression of Nuclear Glucocorticoid Receptor Gene NR3C1 in Newly Diagnosed Myeloma Correlates with Inferior Prognosis and Is Rescued by Thalidomide

Jumping Translocations 1q12 Contribute to Copy Number (CN) Alterations in Multiple Myeloma (MM): Unexpected Focal Amplifications of Receptor Chromosomes (RC)

Bortezomib Induces Activation of b-Catenin/TCF Signaling Pathway in Multiple Myeloma

Loss of CYR61 in Myeloma Microenvironment Is Associated with Poor Survival

Gene Expression Profiling (GEP) Analysis of Plasma Cells (PC) Obtained From MRI-Defined Focal Lesions (FL) Under CT-Guided Fine-Needle Aspiration Provides Better Risk Stratification in Patients with Multiple Myeloma

Gene Expression Profiling Distinguishes Waldenstrom's Macroglobulinemia Patients Presenting with Familial Disease, Advanced IPSS Prognostic Score, and Previous Treatment with Rituximab.

Adoptively Transferred Expanded Natural Killer Cells Inhibit Myeloma Tumor Growth In Vivo .

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American Society of Hematology

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American Society of Hematology

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