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Journal Articles

The GLI-Code As a Potential Therapeutic Target in Myeloid Neoplasms

Sayer Alharbi, PhD, Alek d Nielsen, B.S., Metis Hasipek, PhD, Bartlomiej P Przychodzen, MSc, James G Phillips, PhD, Jaroslaw P Maciejewski, MD PhD FACP, Babal Jha, PhD

Blood (2016) 128 (22): 1655.

https://doi.org/10.1182/blood.V128.22.1655.1655

Published: 2016

Journal Articles

Molecular and Immunophenotypic Characteristics of Adult Acute Leukemias of Ambiguous Lineage

Bhumika Patel, MD, Caner Saygin, MD, Bartlomiej P Przychodzen, MSc, Cassandra M. Hirsch, BSc, Michael J. Clemente, M.S., Betty K. Hamilton, MD, Anjali S. Advani, MD, Aziz Nazha, MD, Sarah Lynn Ondrejka, DO, Matt Kalaycio, MD, Mikkael A. Sekeres, MD MS, Hetty E. Carraway, MD MBA, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 1659.

https://doi.org/10.1182/blood.V128.22.1659.1659

Published: 2016

Journal Articles

Subcutaneous Low Dose Alemtuzumab: Role As a Salvage Therapy in Immune -Mediated Marrow Failure Conditions

Swapna Thota, MD, Srinivasa Reddy Sanikommu, MD, Bhumika Patel, MD, Meena Sadaps, Cassandra M. Hirsch, BSc, Michael J. Clemente, M.S., Serena Marotta, MD, Antonio M Risitano, MD PhD, Mikkael A. Sekeres, MD MS, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 1505.

https://doi.org/10.1182/blood.V128.22.1505.1505

Published: 2016

Journal Articles

Clonal Hierarchy of Piga Mutant Cells Assessed By Next Generation Sequencing Is More Complex Than Previously Recognized in Paroxysmal Noctural Hemoglobinuria

Michael J. Clemente, M.S., Bartlomiej P Przychodzen, MSc, Cassandra M. Hirsch, BSc, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 1506.

https://doi.org/10.1182/blood.V128.22.1506.1506

Published: 2016

Journal Articles

A Single Arm, Phase II Study of Eltrombopag to Enhance Platelet Count Recovery in Older Patients with Acute Myeloid Leukemia Undergoing Remission Induction Therapy

Sudipto Mukherjee, MD, PhD, M.P.H., Paul Elson, PhD, Samjhana Bogati, BSN, Ashley Woltman, BSN, RN, John Desamito, Aaron T. Gerds, MD MS, Hetty E. Carraway, MD MBA, Anjali S. Advani, Yogen Saunthararajah, MD, Jaroslaw P Maciejewski, MD PhD FACP, Matt Kalaycio, MD, Mikkael A. Sekeres, MD MS

Blood (2016) 128 (22): 447.

https://doi.org/10.1182/blood.V128.22.447.447

Published: 2016

Journal Articles

Immunophenotypic Profile and Recurrent Somatic Mutations in 131 Chronic Lymphocytic Leukemia Patients: Low Expression of CD25 in NOTCH1-Mutated Cases

Miriam Castillo, Ana María Hurtado, Tzu Hua Chen-Liang, Julia Muñoz-Ballester, Bartlomiej P Przychodzen, MSc, María Dolores García-Malo, Felipe De Arriba, Francisco José Ortuño, Jaroslaw P. Maciejewski, MD, PhD, FACP, Vicente Vicente, Andres Jerez, MD

Blood (2016) 128 (22): 3201.

https://doi.org/10.1182/blood.V128.22.3201.3201

Published: 2016

Journal Articles

Comparison of the Molecular Spectrum of Lenalidomide-Treated Myelodysplastic Syndrome with and without Del(5q)

Blood (2016) 128 (22): 3172.

https://doi.org/10.1182/blood.V128.22.3172.3172

Published: 2016

Journal Articles

The Mechanism By Which Mutant Nucleophosmin (NPM1) Creates Leukemic Self-Renewal Is Readily Reversed

Xiaorong Gu, PhD, Reda Z. Mahfouz, MD, PhD, Quteba Ebrahem, Francis Enane, Tomas Radivoyevitch, PhD, Michael J. Clemente, M.S., Bartlomiej P Przychodzen, MSc, Zhenbo Hu, MD PhD, Ramesh Balusu, PhD, Claudiu V. Cotta, MD, David N. Wald, MDPhD, Yosef Landesman, PhD, Maria Paola Martelli, MD PhD, Brunangelo Falini, Jaroslaw P Maciejewski, MD PhD FACP, Yogenthiran Saunthararajah, MD

Blood (2016) 128 (22): 444.

https://doi.org/10.1182/blood.V128.22.444.444

Published: 2016

Journal Articles

Impact of Erythropoietic Stimulating Agents on Mutational Composition in Patients with Low-Risk Myelodysplastic Syndromes

Bhumika Patel, MD, Caner Saygin, MD, Bartlomiej P Przychodzen, MSc, Teodora Kuzmanovic, BSc, Cassandra M. Hirsch, BSc, Michael J. Clemente, M.S., Swapna Thota, MD, Aziz Nazha, MD, Sekeres A Mikkael, MD, Jaroslaw P Maciejewski, MD PhD FACP, Hetty E. Carraway, MD MBA

Blood (2016) 128 (22): 2002.

https://doi.org/10.1182/blood.V128.22.2002.2002

Published: 2016

Journal Articles

Molecular and Clinical Characterization of Patients with Myeloid Neoplasms Carrying the 12p Deletion

Vera Adema, PhD, Cassandra M. Hirsch, BSc, Bartlomiej P Przychodzen, MSc, Andrea Pellagatti, PhD, Jacqueline Boultwood, PhD, Aziz Nazha, MD, Hetty E. Carraway, MD MBA, Francesc Sole, PhD, Mikkael A. Sekeres, MD MS, Valeria Visconte, PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP

Blood (2016) 128 (22): 2007.

https://doi.org/10.1182/blood.V128.22.2007.2007

Published: 2016

Journal Articles

Combined Treatment with Lenalidomide (LEN) and Epoetin Alfa (EA) Is Superior to Lenalidomide Alone in Patients with Erythropoietin (Epo)-Refractory, Lower Risk (LR) Non-Deletion 5q [Del(5q)] Myelodysplastic Syndrome (MDS): Results of the E2905 Intergroup Study-an ECOG-ACRIN Cancer Research Group Study, Grant CA180820, and the National Cancer Institute of the National Institutes of Health

Alan F List, MD, Zhuoxin Sun, PhD, Amit Verma, MD, John M. Bennett, MD, Kathy L McGraw, PhD, Lisa Ann Nardelli, BS, Jaroslaw P Maciejewski, MD PhD FACP, Jessica K Altman, MD, Puneet Cheema, MD, David F. Claxton, MD, Rami S. Komrokji, MD, Selina Luger, MD, Ryan Mattison, MD, Tim Wassenaar, MD, Andrew Artz, MD, Charles A Schiffer, MD, Martin S. Tallman, MD

Blood (2016) 128 (22): 223.

https://doi.org/10.1182/blood.V128.22.223.223

Published: 2016

Journal Articles

NGS-Based Copy Number Analysis in 1,185 Patients with Myeloid Neoplasms

Blood (2016) 128 (22): 955.

https://doi.org/10.1182/blood.V128.22.955.955

Published: 2016

Journal Articles

Landscape of Subclonal Mutations in Myelodysplastic Syndromes (MDS) Allows for a Novel Hierarchy of Clonal Advantage By Combining Germline and Somatic Mutations

Blood (2016) 128 (22): 957.

https://doi.org/10.1182/blood.V128.22.957.957

Published: 2016

Journal Articles

Deletion of PTPN1 Promotes the Development of Myelofibrosis

Fatoumata Jobe, PhD, Bhumika Patel, MD, Hideki Makishima, MD PhD, Bartlomiej P Przychodzen, MSc, Robert E Hutchison, MD, Kendra K Bence, PhD, Jaroslaw P Maciejewski, MD PhD FACP, Golam Mohi, PhD

Blood (2016) 128 (22): 795.

https://doi.org/10.1182/blood.V128.22.795.795

Published: 2016

Journal Articles

Quantification of Erythroblast- and Myelocyte-Derived mRNAs in Plasma Exosomes As an Indicator of Bone Marrow Status in Patients with Various Types of Anemias and Myeloproliferative Disorders

Masato Mitsuhashi, MD PhD, Taku Murakami, PhD, Teodora Kuzmanovic, Cassandra M. Hirsch, BSc, Hideki Makishima, MD, PhD, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 5070.

https://doi.org/10.1182/blood.V128.22.5070.5070

Published: 2016

Journal Articles

Clonal Dynamics of Refractory Aplastic Anemia in Patients Treated with Eltrombopag

Bhumika Patel, MD, Bartlomiej P Przychodzen, MSc, Michael J. Clemente, M.S., Cassandra M. Hirsch, BSc, Caner Saygin, MD, Marissa Versalle, MD, Swapna Thota, MD, Aziz Nazha, MD, Roy Souaid, MD, Valeria Visconte, PhD, Taha Bat, MD, Suresh Kumar Balasubramanian, MD, Tomas Radivoyevitch, PhD, Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 3892.

https://doi.org/10.1182/blood.V128.22.3892.3892

Published: 2016

Journal Articles

Current Diagnosis Patterns for Acute Myeloid Leukemia (AML) in Clinical Practice Compared with World Health Organization (WHO) 2008 Recommendations: Outcomes from the CONNECT ® Myelodysplastic Syndromes (MDS) and AML Disease Registry

Blood (2016) 128 (22): 3548.

https://doi.org/10.1182/blood.V128.22.3548.3548

Published: 2016

Journal Articles

Germline Variants of RUNX-1 in Myeloid Malignancy

Alek d Nielsen, B.S., Sayer Alharbi, PhD, Cassandra M. Hirsch, BSc, Bartlomiej P Przychodzen, MSc, Mikkael A. Sekeres, MD MS, Yogen Saunthararajah, MD, Hetty E. Carraway, MD MBA, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 3926.

https://doi.org/10.1182/blood.V128.22.3926.3926

Published: 2016

Journal Articles

Development of ROC-325: A Novel Small Molecule Inhibitor of Autophagy with Promising Anti-Leukemic Activity

Steffan T. Nawrocki, PhD, Yingchun Han, MD, Valeria Visconte, PhD, James G Phillips, PhD, Bartlomiej P Przychodzen, MSc, Jaroslaw P Maciejewski, MD PhD FACP, Kevin R. Kelly, MD PhD, Jennifer S. Carew, PhD

Blood (2016) 128 (22): 525.

https://doi.org/10.1182/blood.V128.22.525.525

Published: 2016

Journal Articles

The Role of LUC7L2 in Splicing and MDS

Courtney Elizabeth Hershberger, BS, Naoko Hosono, MD, PhD, Jarnail Singh, PhD, Rosemary C Dietrich, M.S., Xiaorong Gu, PhD, Hideki Makishima, MD PhD FACP., Yogen Saunthararajah, MD, Jaroslaw P Maciejewski, MD PhD FACP, Richard A Padgett, PhD

Blood (2016) 128 (22): 5504.

https://doi.org/10.1182/blood.V128.22.5504.5504

Published: 2016

NARROW

The GLI-Code As a Potential Therapeutic Target in Myeloid Neoplasms

Molecular and Immunophenotypic Characteristics of Adult Acute Leukemias of Ambiguous Lineage

Subcutaneous Low Dose Alemtuzumab: Role As a Salvage Therapy in Immune -Mediated Marrow Failure Conditions

Clonal Hierarchy of Piga Mutant Cells Assessed By Next Generation Sequencing Is More Complex Than Previously Recognized in Paroxysmal Noctural Hemoglobinuria

A Single Arm, Phase II Study of Eltrombopag to Enhance Platelet Count Recovery in Older Patients with Acute Myeloid Leukemia Undergoing Remission Induction Therapy

Immunophenotypic Profile and Recurrent Somatic Mutations in 131 Chronic Lymphocytic Leukemia Patients: Low Expression of CD25 in NOTCH1-Mutated Cases

Comparison of the Molecular Spectrum of Lenalidomide-Treated Myelodysplastic Syndrome with and without Del(5q)

The Mechanism By Which Mutant Nucleophosmin (NPM1) Creates Leukemic Self-Renewal Is Readily Reversed

Impact of Erythropoietic Stimulating Agents on Mutational Composition in Patients with Low-Risk Myelodysplastic Syndromes

Molecular and Clinical Characterization of Patients with Myeloid Neoplasms Carrying the 12p Deletion

NGS-Based Copy Number Analysis in 1,185 Patients with Myeloid Neoplasms

Landscape of Subclonal Mutations in Myelodysplastic Syndromes (MDS) Allows for a Novel Hierarchy of Clonal Advantage By Combining Germline and Somatic Mutations

Deletion of PTPN1 Promotes the Development of Myelofibrosis

Quantification of Erythroblast- and Myelocyte-Derived mRNAs in Plasma Exosomes As an Indicator of Bone Marrow Status in Patients with Various Types of Anemias and Myeloproliferative Disorders

Clonal Dynamics of Refractory Aplastic Anemia in Patients Treated with Eltrombopag

Current Diagnosis Patterns for Acute Myeloid Leukemia (AML) in Clinical Practice Compared with World Health Organization (WHO) 2008 Recommendations: Outcomes from the CONNECT ® Myelodysplastic Syndromes (MDS) and AML Disease Registry

Germline Variants of RUNX-1 in Myeloid Malignancy

Development of ROC-325: A Novel Small Molecule Inhibitor of Autophagy with Promising Anti-Leukemic Activity

The Role of LUC7L2 in Splicing and MDS

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American Society of Hematology

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