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Francis Enane
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Journal Articles

The Mechanisms By Which Mutant-NPM1 Uncouples Differentiation from Proliferation Are Reversed By Several Drugs, Enabling Rational Multi-Component Non-Cytotoxic Differentiation Therapy

Xiaorong Gu, PhD, Quteba Ebrahem, MD, Reda Z. Mahfouz, MD PhD, Metis Hasipek, PhD, Francis Enane, PhD, Tomas Radivoyevitch, Nicolas Rapin, PhDMSc, Bartlomiej P. Przychodzen, MSc, Ramesh Balusu, PhD, Claudiu V Cotta, David Wald, MD PhD, Zhenbo Hu, MD PhD, Yosef Landesman, PhD, Maria Paola Martelli, MD PhD, Brunangelo Falini, MD, Hetty E. Carraway, MD MBA, Jaroslaw P. Maciejewski, PhD MD FACP, Babal K Jha, PhD, Yogenthiran Saunthararajah, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 878.
https://doi.org/10.1182/blood.V130.Suppl_1.878.878
Published: 2017
Journal Articles

The Mechanism By Which Mutant Nucleophosmin (NPM1) Creates Leukemic Self-Renewal Is Readily Reversed

Xiaorong Gu, PhD, Reda Z. Mahfouz, MD, PhD, Quteba Ebrahem, Francis Enane, Tomas Radivoyevitch, PhD, Michael J. Clemente, M.S., Bartlomiej P Przychodzen, MSc, Zhenbo Hu, MD PhD, Ramesh Balusu, PhD, Claudiu V. Cotta, MD, David N. Wald, MDPhD, Yosef Landesman, PhD, Maria Paola Martelli, MD PhD, Brunangelo Falini, Jaroslaw P Maciejewski, MD PhD FACP, Yogenthiran Saunthararajah, MD
Journal: Blood
Blood (2016) 128 (22): 444.
https://doi.org/10.1182/blood.V128.22.444.444
Published: 2016
Journal Articles

PHF6 - Somatic Mutations and Their Role in Pathophysiology of MDS and AML

Bartlomiej Przychodzen, MSc, Xiaorong Gu, PhD, Dewen You, PhD, Cassandra M. Hirsch, Michael J. Clemente, Aaron D. Viny, MD MS, Ross L. Levine, MD, Torsten Haferlach, Manja Maggendorfer, Mikkael A. Sekeres, MD MS, Hetty E. Carraway, MD MBA, Aziz Nazha, MD, Francis Enane, Jaroslaw P. Maciejewski, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1259.
https://doi.org/10.1182/blood.V126.23.1259.1259
Published: 2015
Journal Articles

A Specific Mechanism By Which NPM1 mutations Impede Myeloid Differentiation Also Explains The Link With DNMT3A Mutation

Xiaorong Gu, PhD, Reda Z Mahfouz, MD/PhD, Francis Enane, MS, Zhenbo Hu, MD, PhD, Michael J. Clemente, Bartlomiej P Przychodzen, PhD, Mikkael A. Sekeres, MD, MS, Anjali S. Advani, MD, Matt Kalaycio, MD, Jaroslaw P. Maciejewski, MD, PhD, Yogen Saunthararajah, M.D.
Journal: Blood
Blood (2013) 122 (21): 1254.
https://doi.org/10.1182/blood.V122.21.1254.1254
Published: 2013