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Journal Articles

A Phase 1 Trial of MEC (Mitoxantrone, Etoposide, Cytarabine) in Combination with Ixazomib (MLN9708) for Relapsed/ Refractory Acute Myeloid Leukemia (AML)

Blood (2016) 128 (22): 4065.

https://doi.org/10.1182/blood.V128.22.4065.4065

Published: 2016

Journal Articles

Phenotype/Genotype Associations in TET2-Driven Myeloid Neoplasms

Cassandra M. Hirsch, BSc, Aziz Nazha, MD, Kassy E Kneen, Bartlomiej P Przychodzen, MSc, Niroshan Nadarajah, M.Sc., Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Torsten Haferlach, MD, Tomas Radivoyevitch, PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP, Manja Meggendorfer, PhD

Blood (2016) 128 (22): 4313.

https://doi.org/10.1182/blood.V128.22.4313.4313

Published: 2016

Journal Articles

Distinct Clinical and Biological Implications of Various DNTMT3A Mutations in Myeloid Neoplasms

Suresh Kumar Balasubramanian, MD, Mai Ali, Taha Bat, MD, Bhumika Patel, MD, Bartlomiej P Przychodzen, MSc, Cassandra M. Hirsch, BSc, Aziz Nazha, MD, Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 2872.

https://doi.org/10.1182/blood.V128.22.2872.2872

Published: 2016

Journal Articles

Subset-Specific Recurrence of Mutations and Identification of Functional Modules Provides New Clues about the Pathogenesis of Large Granular Lymphocyte Leukemia

Alessandro Coppe, BSc, PhD, Emma I Andersson, MSc, Andrea Binatti, BSc, Vanessa R Gasparini, Sabrina Bortoluzzi, Michael J. Clemente, M.S., Marco Herling, MD PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP, Satu Mustjoki, MD PhD, Stefania Bortoluzzi, BSc, PhD

Blood (2016) 128 (22): 4117.

https://doi.org/10.1182/blood.V128.22.4117.4117

Published: 2016

Journal Articles

Is Serial Monitoring of Myeloid Mutations Clinically Relevant in Myelodysplastic Syndromes (MDS): A Report on Behalf of the MDS Clinical Research Consortium (CRC)

Sangmin Lee, MD, John Barnard, PhD, Amy E. DeZern, MD MHS, Jaroslaw P Maciejewski, MD PhD FACP, Najla Alali, MS, David P. Steensma, MD, Ellen K. Ritchie, MD, Pinkal Desai, MD, Guillermo Garcia-Manero, MD, Fatima Ali, B.S., Nicole Rizzo, BA, Duane C Hassane, PhD, Rami S. Komrokji, MD, Mikkael A. Sekeres, MD MS, Gail J. Roboz

Blood (2016) 128 (22): 297.

https://doi.org/10.1182/blood.V128.22.297.297

Published: 2016

Journal Articles

Next-Generation Sequencing Analysis of Clonal Hierarchy and Dynamics in T-Large Granular Lymphocyte Leukemia Suggests Emergence of STAT3 Clones within Pre-Existing Dominant T-Cell Repertoire Responses Otherwise Silenced in Normal Individuals

Peter W Chomczynski, Michael J. Clemente, M.S., Srinivasa Reddy Sanikommu, MD, Alek d Nielsen, B.S., Cassandra M. Hirsch, BSc, Hanna Rajala, MD, Mikkael A. Sekeres, MD MS, Hetty E. Carraway, MD MBA, Satu Mustjoki, MD PhD, Alan E. Lichtin, MD, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 2731.

https://doi.org/10.1182/blood.V128.22.2731.2731

Published: 2016

Journal Articles

PHF6 Somatic Mutations and Their Functional Role in the Pathophysiology of Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Bartlomiej P Przychodzen, MSc, Xiaorong Gu, PhD, Dewen You, PhD, Cassandra M. Hirsch, BSc, Michael J. Clemente, M.S., Mikkael A. Sekeres, MD MS, Aziz Nazha, MD, Hideki Makishima, MD PhD FACP., Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 2736.

https://doi.org/10.1182/blood.V128.22.2736.2736

Published: 2016

Journal Articles

Subcutaneous Low Dose Alemtuzumab: Role As a Salvage Therapy in Immune -Mediated Marrow Failure Conditions

Swapna Thota, MD, Srinivasa Reddy Sanikommu, MD, Bhumika Patel, MD, Meena Sadaps, Cassandra M. Hirsch, BSc, Michael J. Clemente, M.S., Serena Marotta, MD, Antonio M Risitano, MD PhD, Mikkael A. Sekeres, MD MS, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 1505.

https://doi.org/10.1182/blood.V128.22.1505.1505

Published: 2016

Journal Articles

Clonal Hierarchy of Piga Mutant Cells Assessed By Next Generation Sequencing Is More Complex Than Previously Recognized in Paroxysmal Noctural Hemoglobinuria

Michael J. Clemente, M.S., Bartlomiej P Przychodzen, MSc, Cassandra M. Hirsch, BSc, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 1506.

https://doi.org/10.1182/blood.V128.22.1506.1506

Published: 2016

Journal Articles

UTX mutations in Myeloid Neoplasms

Yasunobu Nagata, MD,PhD, Tomas Radivoyevitch, PhD, Hideki Makishima, MD PhD FACP., Cassandra M. Hirsch, BSc, Bartlomiej P Przychodzen, MSc, Teodora Kuzmanovic, BSc, Eiju Negoro, MD, PhD, Michael J. Clemente, M.S., Sudipto Mukherjee, MD, PhD, M.P.H., Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 3148.

https://doi.org/10.1182/blood.V128.22.3148.3148

Published: 2016

Journal Articles

U2AF1 Mutations in S34 and Q157 Create Distinct Molecular and Clinical Contexts

Vera Adema, PhD, Cassandra M. Hirsch, BSc, Bartlomiej P Przychodzen, MSc, Aziz Nazha, MD, Teodora Kuzmanovic, Eiju Negoro, MD, PhD, Dewen You, PhD, Hideki Makishima, MD PhD FACP., Michael J. Clemente, M.S., Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Valeria Visconte, PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP

Blood (2016) 128 (22): 3155.

https://doi.org/10.1182/blood.V128.22.3155.3155

Published: 2016

Journal Articles

Pathogenic Relevance of Germ Line TET2 Alterations

Cassandra M. Hirsch, BSc, Aziz Nazha, MD, Kassy E Kneen, Manja Meggendorfer, PhD, Bartlomiej P Przychodzen, MSc, Niroshan Nadarajah, M.Sc., Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Torsten Haferlach, MD, Thomas LaFramboise, PhD, Tomas Radivoyevitch, PhD, Jaroslaw P. Maciejewski, MD, PhD, FACP

Blood (2016) 128 (22): 3160.

https://doi.org/10.1182/blood.V128.22.3160.3160

Published: 2016

Journal Articles

Immunophenotypic Profile and Recurrent Somatic Mutations in 131 Chronic Lymphocytic Leukemia Patients: Low Expression of CD25 in NOTCH1-Mutated Cases

Miriam Castillo, Ana María Hurtado, Tzu Hua Chen-Liang, Julia Muñoz-Ballester, Bartlomiej P Przychodzen, MSc, María Dolores García-Malo, Felipe De Arriba, Francisco José Ortuño, Jaroslaw P. Maciejewski, MD, PhD, FACP, Vicente Vicente, Andres Jerez, MD

Blood (2016) 128 (22): 3201.

https://doi.org/10.1182/blood.V128.22.3201.3201

Published: 2016

Journal Articles

Comparison of the Molecular Spectrum of Lenalidomide-Treated Myelodysplastic Syndrome with and without Del(5q)

Blood (2016) 128 (22): 3172.

https://doi.org/10.1182/blood.V128.22.3172.3172

Published: 2016

Journal Articles

Clonal Dynamics of Refractory Aplastic Anemia in Patients Treated with Eltrombopag

Bhumika Patel, MD, Bartlomiej P Przychodzen, MSc, Michael J. Clemente, M.S., Cassandra M. Hirsch, BSc, Caner Saygin, MD, Marissa Versalle, MD, Swapna Thota, MD, Aziz Nazha, MD, Roy Souaid, MD, Valeria Visconte, PhD, Taha Bat, MD, Suresh Kumar Balasubramanian, MD, Tomas Radivoyevitch, PhD, Hetty E. Carraway, MD MBA, Mikkael A. Sekeres, MD MS, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 3892.

https://doi.org/10.1182/blood.V128.22.3892.3892

Published: 2016

Journal Articles

Current Diagnosis Patterns for Acute Myeloid Leukemia (AML) in Clinical Practice Compared with World Health Organization (WHO) 2008 Recommendations: Outcomes from the CONNECT ® Myelodysplastic Syndromes (MDS) and AML Disease Registry

Blood (2016) 128 (22): 3548.

https://doi.org/10.1182/blood.V128.22.3548.3548

Published: 2016

Journal Articles

Germline Variants of RUNX-1 in Myeloid Malignancy

Alek d Nielsen, B.S., Sayer Alharbi, PhD, Cassandra M. Hirsch, BSc, Bartlomiej P Przychodzen, MSc, Mikkael A. Sekeres, MD MS, Yogen Saunthararajah, MD, Hetty E. Carraway, MD MBA, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 3926.

https://doi.org/10.1182/blood.V128.22.3926.3926

Published: 2016

Journal Articles

the Impact of Clonal Dynamics on Prognosis and Outcome in Myelodysplastic Syndromes

Hideki Makishima, MD PhD FACP., Tetsuichi Yoshizato, MD PhD, Kenichi Yoshida, MD PhD, Mikkael A. Sekeres, MD MS, Tomas Radivoyevitch, PhD, Hiromichi Suzuki, MD PhD, Bartlomiej P Przychodzen, MSc, Yasunobu Nagata, MD, PhD, Manja Meggendorfer, PhD, Masashi Sanada, MD PhD, Yusuke Okuno, MD PhD, Cassandra M. Hirsch, BSc, Teodora Kuzmanovic, Yusuke Shiozawa, MD, Yusuke Sato, MD PhD, Aiko Sato-Otsubo, Thomas LaFramboise, PhD, Naoko Hosono, MD, PhD, Yuichi Shiraishi, PhD, Kenichi Chiba, BA, Claudia Haferlach, MD, Wolfgang Kern, MD, Hiroko Tanaka, BA, Ines Gómez-Seguí, MD PhD, Holleh Husseinzadeh, MD, Swapna Thota, MD, Kathryn M. Guinta, Brittney Dienes, Tsuyoshi Nakamaki, MD, Shuichi Miyawaki, MD PhD, Yogen Saunthararajah, MD, Shigeru Chiba, MD, PhD, Satoru Miyano, PhD, Lee-Yung Shih, MD, Torsten Haferlach, MD, Seishi Ogawa, MD PhD, Jaroslaw P Maciejewski, MD PhD FACP

Blood (2016) 128 (22): 4287.

https://doi.org/10.1182/blood.V128.22.4287.4287

Published: 2016

Journal Articles

Clonal Events of Aplastic Anemia Related to the Evolution to Myelodysplastic Syndrome

Eiju Negoro, MD, PhD, Michael Clemente, M.S., Naoko Hosono, MD,PhD, Aziz Nazha, MD, Wenyi Shen, MD, Yasunobu Nagata, MD, PhD, Cassandra M. Hirsch, BSc, Bartlomiej P Przychodzen, MSc, Reda Z. Mahfouz, MD, PhD, Teodora Kuzmanovic, BSc, Hideki Makishima, MD PhD FACP., Mikkael A. Sekeres, MD MS, Jaroslaw P. Maciejewski, MD, PhD, FACP

Blood (2016) 128 (22): 4290.

https://doi.org/10.1182/blood.V128.22.4290.4290

Published: 2016

Journal Articles

Analysis of Outcomes of Patients with Relapsed/Refractory Acute Myeloid Leukemia Treated in Randomized Clinical Trials

Raffi Tchekmedyian, BS, Paul Elson, PhD, Aaron T. Gerds, MD MS, Navneet Majhail, MD MS, Hetty E. Carraway, MD MBA, Anjali S. Advani, MD, Aziz Nazha, MD, Jaroslaw P Maciejewski, MD PhD FACP, Matt Kalaycio, MD FACP, Mikkael A. Sekeres, MD MS, Sudipto Mukherjee, MD, PhD, M.P.H.

Blood (2016) 128 (22): 4000.

https://doi.org/10.1182/blood.V128.22.4000.4000

Published: 2016

NARROW

A Phase 1 Trial of MEC (Mitoxantrone, Etoposide, Cytarabine) in Combination with Ixazomib (MLN9708) for Relapsed/ Refractory Acute Myeloid Leukemia (AML)

Phenotype/Genotype Associations in TET2-Driven Myeloid Neoplasms

Distinct Clinical and Biological Implications of Various DNTMT3A Mutations in Myeloid Neoplasms

Subset-Specific Recurrence of Mutations and Identification of Functional Modules Provides New Clues about the Pathogenesis of Large Granular Lymphocyte Leukemia

Is Serial Monitoring of Myeloid Mutations Clinically Relevant in Myelodysplastic Syndromes (MDS): A Report on Behalf of the MDS Clinical Research Consortium (CRC)

Next-Generation Sequencing Analysis of Clonal Hierarchy and Dynamics in T-Large Granular Lymphocyte Leukemia Suggests Emergence of STAT3 Clones within Pre-Existing Dominant T-Cell Repertoire Responses Otherwise Silenced in Normal Individuals

PHF6 Somatic Mutations and Their Functional Role in the Pathophysiology of Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Subcutaneous Low Dose Alemtuzumab: Role As a Salvage Therapy in Immune -Mediated Marrow Failure Conditions

Clonal Hierarchy of Piga Mutant Cells Assessed By Next Generation Sequencing Is More Complex Than Previously Recognized in Paroxysmal Noctural Hemoglobinuria

UTX mutations in Myeloid Neoplasms

U2AF1 Mutations in S34 and Q157 Create Distinct Molecular and Clinical Contexts

Pathogenic Relevance of Germ Line TET2 Alterations

Immunophenotypic Profile and Recurrent Somatic Mutations in 131 Chronic Lymphocytic Leukemia Patients: Low Expression of CD25 in NOTCH1-Mutated Cases

Comparison of the Molecular Spectrum of Lenalidomide-Treated Myelodysplastic Syndrome with and without Del(5q)

Clonal Dynamics of Refractory Aplastic Anemia in Patients Treated with Eltrombopag

Current Diagnosis Patterns for Acute Myeloid Leukemia (AML) in Clinical Practice Compared with World Health Organization (WHO) 2008 Recommendations: Outcomes from the CONNECT ® Myelodysplastic Syndromes (MDS) and AML Disease Registry

Germline Variants of RUNX-1 in Myeloid Malignancy

the Impact of Clonal Dynamics on Prognosis and Outcome in Myelodysplastic Syndromes

Clonal Events of Aplastic Anemia Related to the Evolution to Myelodysplastic Syndrome

Analysis of Outcomes of Patients with Relapsed/Refractory Acute Myeloid Leukemia Treated in Randomized Clinical Trials

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American Society of Hematology

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American Society of Hematology

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