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Janne Lehtiö
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Journal Articles

Resistance to FLT3 Inhibitors in FLT3-Mutated AML Is Associated with CD45RA + CD200 - leukemic Cells and Can be Overcome By Combination with SMAC Mimetics

Nona Struyf, Henrik Gezelius, Anders Lundmark, Chiara Barizza, Hidde Ploeger, Lucía Rico Pizarro, Mattias Vesterlund, Georgios Mermelekas, Albin Osterroos, Anna Bohlin, Sofia Bengtzén, Kerstin Hamberg Levedahl, Rozbeh Jafari, Lukas M Orre, Janne Lehtiö, Päivi Östling, Brinton Seashore-Ludlow, Jessica Nordlund, Soren Lehmann, Olli Kallioniemi, Tom Erkers
Journal: Blood
Blood (2024) 144 (Supplement 1): 1565.
https://doi.org/10.1182/blood-2024-200093
Published: 2024
Journal Articles

SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma

Mohammad Hamdy Abdelrazak Morsy, Ingrid Lilienthal, Martin Lord, Magali Merrien, Agata Magdalena Wasik, Marta Sureda-Gómez, Virginia Amador, Henrik J. Johansson, Janne Lehtiö, Beatriz Garcia-Torre, Jose Ignacio Martin-Subero, Nikolaos Tsesmetzis, Sijia Tao, Raymond F. Schinazi, Baek Kim, Agnes L. Sorteberg, Malin Wickström, Devon Sheppard, Georgios Z. Rassidakis, Ian A. Taylor, Birger Christensson, Elias Campo, Nikolas Herold, Birgitta Sander
Journal: Blood
Blood (2024) 143 (19): 1953–1964.
https://doi.org/10.1182/blood.2023022241
Published: 2024
Includes: Supplemental data
Journal Articles

Data-Driven Molecular Hallmarks of Acute Myeloid Leukemia: Biological, Prognostic and Therapeutic Implications

Tom Erkers, Francesco Marabita, Nona Struyf, Mattias Vesterlund, Tojo James, Cornelia Arnroth, Anna Bohlin, Sofia Bengtzén, Albin Österroos, Matthias Stahl, Rozbeh Jafari, Lukas Orre, Yudi Pawitan, Brinton Seashore-Ludlow, Janne Lehtiö, Sören Lehmann, Päivi Östling, Olli Kallioniemi
Journal: Blood
Blood (2022) 140 (Supplement 1): 6299.
https://doi.org/10.1182/blood-2022-163046
Published: 2022
Journal Articles

Proteogenomic Subtyping of Chronic Lymphocytic Leukemia Identifies a Novel Poor Outcome Subgroup with a Distinct Drug Response Profile

Sophie A. Herbst, MSc, Mattias Vesterlund, Rozbeh Jafari, PhD, Ioannis Siavelis, Matthias Stahl, Eva Schitter, Alexander J. Helmboldt, Murat Iskar, Nora Liebers, MD, Felix Czernilofsky, Tobias Roider, MD, Peter-Martin Bruch, Junyan Lu, Sarah Richter, Georgios Mermelekas, Husen Muhammad Umer, Mareike Knoll, Carolin Kolb, Angela Lenze, Xiaofang Cao, Cecilia Österholm-Corbascio, Sebastian Scheinost, Matthias Ganzinger, Larry Mansouri, PhD, Katharina Kriegsmann, MD, Mark Kriegsmann, MD, Carsten Mueller-Tidow, MD, Peter Dreger, MD, Simon Anders, PhD, Marc Zapatka, Marco Herling, MD, Richard Rosenquist, MD, Stephan Stilgenbauer, MD, Thorsten Zenz, Wolfgang Huber, PhD, Eugen Tausch, MD, Janne Lehtiö, Sascha Dietrich, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10–11.
https://doi.org/10.1182/blood-2020-137528
Published: 2020
Journal Articles

High-Throughput Functional Ex-Vivo Drug Testing and Multi-Omics Profiling in Patients with Acute Myeloid Leukemia

Tom Erkers, PhD, Brinton Seashore-Ludlow, Nona Struyf, Francesco Marabita, Tojo James, Disha Malani, Mattias Vesterlund, Matthias Stalhl, Yudi Pawitan, Sören Lehmann, MD PhD, Päivi Östling, Janne Lehtiö, Olli Kallioniemi
Journal: Blood
Blood (2019) 134 (Supplement_1): 4641.
https://doi.org/10.1182/blood-2019-124332
Published: 2019
Journal Articles

The Proteogenomic Landscape of High Hyperdiploid and ETV6/RUNX1-Positive Childhood Acute Lymphoblastic Leukemia

Minjun Yang, Mattias Vesterlund, Ioannis Siavelis, Eleanor Woodward, Naveen Ravi, Henrik Lilljebjörn, MSc, Thoas Fioretos, MD PhD, Janne Lehtiö, Kajsa Paulsson
Journal: Blood
Blood (2017) 130 (Supplement 1): 1433.
https://doi.org/10.1182/blood.V130.Suppl_1.1433.1433
Published: 2017