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Journal Articles

The miRNA-193 Family Is a Potent Tumor-Suppressor and a Biomarker for Poor Prognosis in Acute Myeloid Leukemia

Blood (2016) 128 (22): 1534.

https://doi.org/10.1182/blood.V128.22.1534.1534

Published: 2016

Journal Articles

Successes and Challenges of Pediatric AML: A Report on Survival, Salvage Therapy and Causes of Deaths in the AML-BFM Study Group from 1987 -2012

Mareike Rasche, MD, Martin Zimmermann, PhD, Lisa Kellerstrass, Ursula Creutzig, MD PhD, Jan-Henning Klusmann, MD, Dirk Reinhardt, MD PhD

Blood (2016) 128 (22): 450.

https://doi.org/10.1182/blood.V128.22.450.450

Published: 2016

Journal Articles

Members of the Mir-99/100~125 Tricistrons Cooperatively Induce a Pre-Leukemic Myeloproliferative Disorder

Stephan Emmrich, PhD, Sarva Keihani, Msc, Dirk Reinhardt, MD, Jan-Henning Klusmann, MD

Blood (2015) 126 (23): 3579.

https://doi.org/10.1182/blood.V126.23.3579.3579

Published: 2015

Journal Articles

Integrated Analysis of the Human Hematopoietic Non-Coding RNA Landscape Reveals Lnc-RNA Stem Cell Signature in AML

Adrian Schwarzer, MD PhD, Stephan Emmrich, PhD MSc, Franziska Schmidt, Damian Witte, Aliaksandra Maroz, Dirk Reinhardt, MD, Jan-Henning Klusmann, MD

Blood (2015) 126 (23): 45.

https://doi.org/10.1182/blood.V126.23.45.45

Published: 2015

Journal Articles

The Mir-193 Family Antagonizes Stem Cell Pathways and Is a Potent Tumor Suppressor in Childhood and Adult Acute Myeloid Leukemia

Blood (2015) 126 (23): 1244.

https://doi.org/10.1182/blood.V126.23.1244.1244

Published: 2015

Journal Articles

Crispr-Cas9 Induced MLL-Rearrangements Cause Clonal Outgrowth in CD34+ Hematopoietic Stem Cells

Jana Reimer, Sabine Knoess, Maurice Labuhn, Emmanuelle Marie Charpentier, PhD, Jan-Henning Klusmann, MD, Dirk Heckl, PhD

Blood (2015) 126 (23): 165.

https://doi.org/10.1182/blood.V126.23.165.165

Published: 2015

Journal Articles

Microrna-106b~25 Cluster Is Involved in Relapsed MLL -Rearranged Pediatric AML

Lonneke Verboon, Maarten Fornerod, PhD, Askar Obulkasim, Edwin Sonneveld, PhD, André Baruchel, MD, Jan Trka, MD PhD, Dirk Reinhardt, MD PhD, Rob Pieters, MD PhD, Jacqueline Cloos, PhD, Gertjan JL Kaspers, MD PhD, Jan-Henning Klusmann, MD, C. Michel Zwaan, MD PhD, Marry van den Heuvel-Eibrink, MD PhD

Blood (2014) 124 (21): 1038.

https://doi.org/10.1182/blood.V124.21.1038.1038

Published: 2014

Journal Articles

GATA1-Centered Genetic Network on Chromosome 21 Drives Down Syndrome Acute Megakaryoblastic Leukemia

Lena Stachorski, Dirk Heckl, PhD, Veera Raghavan Thangapandi, Aliaksandra Maroz, PhD, Dirk Reinhardt, MD PhD, Jan-Henning Klusmann, MD

Blood (2014) 124 (21): 4310.

https://doi.org/10.1182/blood.V124.21.4310.4310

Published: 2014

Journal Articles

the miR-99∼125 P olycistrons Promote Leukemogenesis in a Cell-Context Dependent Manner by Shifting the Balance Between TGFβ- and Wnt-Signaling

Stephan Emmrich, Mareike Rasche, Jennifer Schöning, Zhe Li, PhD, Axel Schambach, MD PhD, Dirk Reinhardt, MD, Jan-Henning Klusmann, MD

Blood (2012) 120 (21): 109.

https://doi.org/10.1182/blood.V120.21.109.109

Published: 2012

Journal Articles

Reduced Erg Dosage Perturbs Fetal and Adult Hematopoiesis

Mia Lee Koch, Xin Zhang, Melanie Hamblen, Frank Godinho, Dirk Reinhardt, MD, Jan-Henning Klusmann, MD, Stuart H. Orkin, MD, Zhe Li, PhD

Blood (2012) 120 (21): 1189.

https://doi.org/10.1182/blood.V120.21.1189.1189

Published: 2012

Journal Articles

GATA1s Induces Hyperproliferation of Eosinophil Precursors.

Aliaksandra Maroz, Katarina Reinhardt, PhD, Johann K. Hitzler, MD, Irene Roberts, Christian Hennig, MD, Gesine Hansen, MD, PhD, Dirk Reinhardt, MD, Jan-Henning Klusmann, MD

Blood (2012) 120 (21): 2318.

https://doi.org/10.1182/blood.V120.21.2318.2318

Published: 2012

Journal Articles

Acetylation of p53 Is Involved in Valproic Acid Induced Death of AML Cells

Basant Kumar Thakur, PhD, Tino Dittrich, Karl Welte, MD, Jan-Henning Klusmann, MD, Dirk Reinhardt, MD

Blood (2011) 118 (21): 2461.

https://doi.org/10.1182/blood.V118.21.2461.2461

Published: 2011

Journal Articles

GATA1s Exerts Fetal Stage-Specific Oncogenic Effects in Human Hematopoietic Stem and Progenitor Cells

Aliaksandra Maroz, Ben Van Handel, Hanna Mikkola, MD, PhD, Jennifer Schoenning, Dirk Reinhardt, MD, PhD, Jan-Henning Klusmann, MD

Blood (2011) 118 (21): 2355.

https://doi.org/10.1182/blood.V118.21.2355.2355

Published: 2011

Journal Articles

Next Generation Sequencing for Minimal Residual Disease Monitoring in AML Patients with FLT3-ITD,

Felicitas Thol, Frederik Damm, Katharina Wagner, Katarina Reinhardt, Jan-Henning Klusmann, MD, Nils von Neuhoff, Brigitte Schlegelberger, MD, Dirk Reinhardt, MD, PhD, Jürgen Krauter, Arnold Ganser, MD, Michael Heuser, M.D.

Blood (2011) 118 (21): 3548.

https://doi.org/10.1182/blood.V118.21.3548.3548

Published: 2011

Journal Articles

mTOR Pathway Links Suppressed Autophagy to HDAC Inhibitor-Induced Apoptosis in Myeloid Leukemia,

Metodi V. Stankov, PhD, Kirsten Heitmann, Zhe Li, PhD, Basant Kumar Thakur, PhD, Diana Panayotova-Dimitrova, PhD, Jennifer Schöning, Jean-Pierre Bourquin, MD, PhD, Tino Dittrich, Stephan Emmrich, Nora Schweitzer, MD, Martin Leverkus, MD, Dirk Reinhardt, MD, PhD, Stuart H. Orkin, MD, Georg M.N. Behrens, MD, Jan-Henning Klusmann, MD

Blood (2011) 118 (21): 3614.

https://doi.org/10.1182/blood.V118.21.3614.3614

Published: 2011

Journal Articles

Deciphering the Role of Mir-99∼125 clusters in the Hematopoietic System

Stephan Emmrich, Kerstin Henke, Zhe Li, PhD, Jennifer Schöning, Axel Schambach, MD PhD, Dirk Reinhardt, MD, PhD, Jan-Henning Klusmann, MD

Blood (2011) 118 (21): 213.

https://doi.org/10.1182/blood.V118.21.213.213

Published: 2011

Journal Articles

Gene Expression-Based Chemical Genomics Identifies Valproic Acid to Revert the Oncogenic Effect of GATA1s In Down Syndrome Megakaryoblastic Leukemia.

Kirsten Heitmann, Zhe Li, PhD, Jan-Henning Klusmann, MD, Basant Kumar Thakur, PhD, Jennifer Schöning, Jean-Pierre Bourquin, MD, PhD, Stuart H. Orkin, MD, Dirk Reinhardt, MD, PhD

Blood (2010) 116 (21): 3646.

https://doi.org/10.1182/blood.V116.21.3646.3646

Published: 2010

Journal Articles

Is Prevention of Myeloid Leukemia Possible?.

Katarina Reinhardt, Marjolein Blink, MD, Annette Sander, Christine von Neuhoff, Katarina Boehmer, Alexandra Kolenova, Jan Stary, Denisa Mendelova, Jan-Henning Klusmann, MD, Dominik Schneider, Valerie de Haas, MD, PhD, Claudia Rossig, MD, Marry M. van den Heuvel, MD, PhD, Ursula Creutzig, MD, C. Michel Zwaan, MD, PhD, Dirk Reinhardt, MD, PhD

Blood (2009) 114 (22): 481.

https://doi.org/10.1182/blood.V114.22.481.481

Published: 2009

Journal Articles

Developmental Stage-Specific Interplay Between GATA1 and IGF Signaling in Fetal Hematopoiesis and Leukemogenesis.

Jan-Henning Klusmann, MD, Frank Godinho, Kirsten Heitmann, Aliaksandra Maroz, Dirk Reinhardt, MD, PhD, Stuart H Orkin, MD, Zhe Li, PhD

Blood (2009) 114 (22): 386.

https://doi.org/10.1182/blood.V114.22.386.386

Published: 2009

Journal Articles

GATA1 Mutations in Transient Leukemia and Myeloid Leukemia in “Down” Syndrome.

Katarina Reinhardt, PhD, Katarina Boehmer, Jan-Henning Klusmann, MD, Manuela Germeshausen, PhD, Annette Sander, MD, Christine von Neuhoff, MD, Jan Stary, MD, PhD, Heribert Jürgens, MD, PhD, Arnulf Pekrun, MD, PhD, Axel Sauerbrey, MD, PhD, Charlotte M Niemeyer, MD, PhD, Gudrun Fleischhack, MD, PhD, Ursula Creutzig, MD, PhD, Dirk Reinhardt, MD, PhD

Blood (2008) 112 (11): 923.

https://doi.org/10.1182/blood.V112.11.923.923

Published: 2008

NARROW

The miRNA-193 Family Is a Potent Tumor-Suppressor and a Biomarker for Poor Prognosis in Acute Myeloid Leukemia

Successes and Challenges of Pediatric AML: A Report on Survival, Salvage Therapy and Causes of Deaths in the AML-BFM Study Group from 1987 -2012

Members of the Mir-99/100~125 Tricistrons Cooperatively Induce a Pre-Leukemic Myeloproliferative Disorder

Integrated Analysis of the Human Hematopoietic Non-Coding RNA Landscape Reveals Lnc-RNA Stem Cell Signature in AML

The Mir-193 Family Antagonizes Stem Cell Pathways and Is a Potent Tumor Suppressor in Childhood and Adult Acute Myeloid Leukemia

Crispr-Cas9 Induced MLL-Rearrangements Cause Clonal Outgrowth in CD34+ Hematopoietic Stem Cells

Microrna-106b~25 Cluster Is Involved in Relapsed MLL -Rearranged Pediatric AML

GATA1-Centered Genetic Network on Chromosome 21 Drives Down Syndrome Acute Megakaryoblastic Leukemia

the miR-99∼125 P olycistrons Promote Leukemogenesis in a Cell-Context Dependent Manner by Shifting the Balance Between TGFβ- and Wnt-Signaling

Reduced Erg Dosage Perturbs Fetal and Adult Hematopoiesis

GATA1s Induces Hyperproliferation of Eosinophil Precursors.

Acetylation of p53 Is Involved in Valproic Acid Induced Death of AML Cells

GATA1s Exerts Fetal Stage-Specific Oncogenic Effects in Human Hematopoietic Stem and Progenitor Cells

Next Generation Sequencing for Minimal Residual Disease Monitoring in AML Patients with FLT3-ITD,

mTOR Pathway Links Suppressed Autophagy to HDAC Inhibitor-Induced Apoptosis in Myeloid Leukemia,

Deciphering the Role of Mir-99∼125 clusters in the Hematopoietic System

Gene Expression-Based Chemical Genomics Identifies Valproic Acid to Revert the Oncogenic Effect of GATA1s In Down Syndrome Megakaryoblastic Leukemia.

Is Prevention of Myeloid Leukemia Possible?.

Developmental Stage-Specific Interplay Between GATA1 and IGF Signaling in Fetal Hematopoiesis and Leukemogenesis.

GATA1 Mutations in Transient Leukemia and Myeloid Leukemia in “Down” Syndrome.

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American Society of Hematology

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American Society of Hematology

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