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Maurice Labuhn
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Journal Articles

RUNX1 isoform disequilibrium promotes the development of trisomy 21–associated myeloid leukemia

Sofia Gialesaki, Daniela Bräuer-Hartmann, Hasan Issa, Raj Bhayadia, Oriol Alejo-Valle, Lonneke Verboon, Anna-Lena Schmell, Stephanie Laszig, Enikő Regényi, Konstantin Schuschel, Maurice Labuhn, Michelle Ng, Robert Winkler, Christian Ihling, Andrea Sinz, Markus Glaß, Stefan Hüttelmaier, Sören Matzk, Lena Schmid, Farina Josepha Strüwe, Sofie-Katrin Kadel, Dirk Reinhardt, Marie-Laure Yaspo, Dirk Heckl, Jan-Henning Klusmann
Journal: Blood
Blood (2023) 141 (10): 1105–1118.
https://doi.org/10.1182/blood.2022017619
Published: 2023
Includes: Supplemental data
Journal Articles

The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis

Oriol Alejo-Valle, Karoline Weigert, Raj Bhayadia, Michelle Ng, Hasan Issa, Christoph Beyer, Stephan Emmrich, Konstantin Schuschel, Christian Ihling, Andrea Sinz, Martin Zimmermann, Claudia Wickenhauser, Marius Flasinski, Eniko Regenyi, Maurice Labuhn, Dirk Reinhardt, Marie-Laure Yaspo, Dirk Heckl, Jan-Henning Klusmann
Journal: Blood
Blood (2022) 139 (5): 651–665.
https://doi.org/10.1182/blood.2021012231
Published: 2022
Includes: Supplemental data
Journal Articles

Modelling the Progression of a Preleukemic Stage to Overt Leukemia in Children with Down Syndrome

Maurice Labuhn, MSc, Kelly Perkins, PhD, Elli Papaemmanuil, PhD, Catherine Garnett, Soeren Matzk, Vyacheslav Amstislavskiy, Marlen Metzner, Alison Kennedy, Carina Scheer, Kenichi Yoshida, MD PhD, Adrian Schwarzer, MD PhD, John D. Crispino, PhD MBA, Jeffrey W. Taub, MD, Mitchell J. Weiss, MD PhD, Etsuro Ito, MDPhD, Seishi Ogawa, MD PhD, Dirk Reinhardt, Marie-Laure Yaspo, PhD, Peter J. Campbell, PhD, Dirk Heckl, PhD, Jan-Henning Klusmann, Paresh Vyas
Journal: Blood
Blood (2018) 132 (Supplement 1): 543.
https://doi.org/10.1182/blood-2018-99-116661
Published: 2018
Journal Articles

Crispr-Cas9 Induced MLL-Rearrangements Cause Clonal Outgrowth in CD34+ Hematopoietic Stem Cells

Jana Reimer, Sabine Knoess, Maurice Labuhn, Emmanuelle Marie Charpentier, PhD, Jan-Henning Klusmann, MD, Dirk Heckl, PhD
Journal: Blood
Blood (2015) 126 (23): 165.
https://doi.org/10.1182/blood.V126.23.165.165
Published: 2015