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Jan Roodt
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Journal Articles

N -acetylcysteine in preclinical mouse and baboon models of thrombotic thrombocytopenic purpura

Claudia Tersteeg, Jan Roodt, Walter J. Van Rensburg, Charlotte Dekimpe, Nele Vandeputte, Inge Pareyn, Aline Vandenbulcke, Barbara Plaimauer, Seb Lamprecht, Hans Deckmyn, José A. Lopez, Simon F. De Meyer, Karen Vanhoorelbeke
Journal: Blood
Blood (2017) 129 (8): 1030–1038.
https://doi.org/10.1182/blood-2016-09-738856
Published: 2017
Includes: Supplemental data
Journal Articles

Evaluation of efficacy and safety of the anti-VWF Nanobody ALX-0681 in a preclinical baboon model of acquired thrombotic thrombocytopenic purpura

Filip Callewaert, Jan Roodt, Hans Ulrichts, Thomas Stohr, Walter Janse van Rensburg, Seb Lamprecht, Stefaan Rossenu, Sofie Priem, Wouter Willems, Josefin-Beate Holz
Journal: Blood
Blood (2012) 120 (17): 3603–3610.
https://doi.org/10.1182/blood-2012-04-420943
Published: 2012
Includes: Supplemental data
Journal Articles

Inhibition of von Willebrand factor–platelet glycoprotein Ib interaction prevents and reverses symptoms of acute acquired thrombotic thrombocytopenic purpura in baboons

Brief Report
Hendrik B. Feys, Jan Roodt, Nele Vandeputte, Inge Pareyn, Harald Mottl, Sam Hou, Seb Lamprecht, Walter J. Van Rensburg, Hans Deckmyn, Karen Vanhoorelbeke
Journal: Blood
Blood (2012) 120 (17): 3611–3614.
https://doi.org/10.1182/blood-2012-04-421248
Published: 2012
Includes: Supplemental data
Journal Articles

Antithrombotic drug candidate ALX-0081 shows superior preclinical efficacy and safety compared with currently marketed antiplatelet drugs

Hans Ulrichts, Karen Silence, Anne Schoolmeester, Peter de Jaegere, Stefaan Rossenu, Jan Roodt, Sofie Priem, Marc Lauwereys, Peter Casteels, Femke Van Bockstaele, Katrien Verschueren, Patrick Stanssens, Judith Baumeister, Josefin-Beate Holz
Journal: Blood
Blood (2011) 118 (3): 757–765.
https://doi.org/10.1182/blood-2010-11-317859
Published: 2011
Includes: Supplemental data
Journal Articles

Thrombotic thrombocytopenic purpura directly linked with ADAMTS13 inhibition in the baboon ( Papio ursinus )

Hendrik B. Feys, Jan Roodt, Nele Vandeputte, Inge Pareyn, Seb Lamprecht, Walter J. van Rensburg, Patricia J. Anderson, Ulrich Budde, Vernon J. Louw, Philip N. Badenhorst, Hans Deckmyn, Karen Vanhoorelbeke
Journal: Blood
Blood (2010) 116 (12): 2005–2010.
https://doi.org/10.1182/blood-2010-04-280479
Published: 2010
Includes: Supplemental data
Journal Articles

ALX-0081 Nanobody ™ , an Engineered Bivalent Anti-Thrombotic Drug Candidate with Improved Efficacy and Safety as Compared to the Marketed Drugs.

Karen Silence, Heidi Jonckheere, Peter Casteels, Jan Roodt, Muriel Meiring, Seb Lamprecht, Martin IJsseldijk, Kristi de Smet, Bob van der Jeugt, Flip de Groot, Torsten Dreier
Journal: Blood
Blood (2006) 108 (11): 896.
https://doi.org/10.1182/blood.V108.11.896.896
Published: 2006
Journal Articles

The Determination of the Inhibitory Activity of Some Factor VIII Type II Inhibitor Antibodies Is Biased by the Type of Factor VIII Assay.

Marc G. Jacquemin, MD, Seb Lamprecht, MSc, Renaud Lavend’homme, MSc, Jan Roodt, MSc, Bernard Chatelain, MD, Veronique Deneys, MD, Jeroen Dewaele, MSc, Jean-Marie Stassen, PhD, Muriel Meiring, PhD, Jean Marie Saint-Remy, MD, Henry Pieters, PhD, Philip Badenhorst, MD
Journal: Blood
Blood (2005) 106 (11): 3200.
https://doi.org/10.1182/blood.V106.11.3200.3200
Published: 2005
Journal Articles

An Animal Model Suitable for Predicting In Vivo Behavior of Platelets in Humans: A Tool for New Product Development.

Morris A. Blajchman, Junzhi Li, Myron Kulczycky, Zofia Woskowska, Henry Pieters, Jan Roodt, Philip Badenhorst, Robert Crookes, Anthon Heyns, Raymond Goodrich
Journal: Blood
Blood (2004) 104 (11): 3628.
https://doi.org/10.1182/blood.V104.11.3628.3628
Published: 2004