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Jacob Aptekar
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Journal Articles

Secondary Hematologic Malignancies in Patients Following Chimeric Antigen Receptor T-Cell Therapy: Aggregated Clinical Trial Data from 1542 Patients

Edward R Scheffer Cliff, Penelope Lafeuille, Sheila Diamond, Jacob Aptekar, David A Russler-Germain, Kai Rejeski, Aaron S Kesselheim
Journal: Blood
Blood (2024) 144 (Supplement 1): 2077.
https://doi.org/10.1182/blood-2024-203979
Published: 2024
Journal Articles

Using Synthetic Data Produced By Artificial Intelligence (AI) to Generate Insights for Chimeric Antigen Receptor T-Cell (CAR T-Cell) Clinical Trials

Penelope Lafeuille, Afrah Shafquat, Chao Sang, Mandis Beigi, Francesco Maura, Jacob Aptekar
Journal: Blood
Blood (2024) 144 (Supplement 1): 7484.
https://doi.org/10.1182/blood-2024-203356
Published: 2024
Journal Articles

Phosphorus Disruption Is Associated with the Incidence and Severity of Neurotoxicity Symptoms in CD19-Targeted CAR-T Cell Therapy: A Pooled Clinical Trial Analysis

Penelope Lafeuille, Sheila Diamond, Alexandru Socolov, Jacob Aptekar, Theodore Nowicki
Journal: Blood
Blood (2023) 142 (Supplement 1): 3626.
https://doi.org/10.1182/blood-2023-182138
Published: 2023
Journal Articles

Immune Checkpoint Inhibitors and the Risk of Cardiovascular Adverse Events: A Pooled Clinical Trial Database Analysis

Kayleen Ports, Rahul Jain, Sheila Diamond, Jacob Aptekar, David C. Fajgenbaum
Journal: Blood
Blood (2023) 142 (Supplement 1): 6933.
https://doi.org/10.1182/blood-2023-181968
Published: 2023
Journal Articles

Machine Learning-Based Decision Tree for Identifying and Grading Severity of Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS) Based on Neurological Adverse Events in Patients Treated with CD19 CAR-T

Alexandru Socolov, Penelope Lafeuille, Sheila Diamond, Eric Yang, Francesco Maura, Jacob Aptekar, Esther Nie
Journal: Blood
Blood (2023) 142 (Supplement 1): 5018.
https://doi.org/10.1182/blood-2023-182147
Published: 2023
Journal Articles

Significant Cytokine Release Syndrome Risk Model with T-Cell Engaging Therapies

Penelope Lafeuille, William Blumentals, Claire Brulle Wohlhueter, Weixi Chen, Chao Sang, Sydney Manning, Silvy Saltzman, Jan Canvin, Susan Richard, Cris Kamperschroer, Giovanni Abbadessa, Aniketh Talwai, Caroline Der-Nigoghossian, Yahav Itzkovich, Vibhu Agarwal, Rahul Jain, Tanmay Jain, Jacob Aptekar, Stephan Grupp
Journal: Blood
Blood (2023) 142 (Supplement 1): 3629.
https://doi.org/10.1182/blood-2023-181985
Published: 2023
Journal Articles

Deriving Predictive Features of Severe CRS from Pre-Infusion Clinical Data in CAR T-Cell Therapies

Vibhu Agarwal, Jacob Aptekar, David C Fajgenbaum, Penelope Lafeuille
Journal: Blood
Blood (2022) 140 (Supplement 1): 7838–7839.
https://doi.org/10.1182/blood-2022-169287
Published: 2022
Journal Articles

Patterns of Hematologic Function and Cytokine Release Syndrome Severity in ALL Patients Receiving CAR-T and TCR-T Therapies Using Pooled Clinical Trial Data

Vibhu Agarwal, Alexandru Socolov, Robert Buderi, Emelly Rusli, Lilia Bouzit, Aniketh Talwai, Yahav Itzkovich, Aaron Galaznik, Jacob Aptekar
Journal: Blood
Blood (2021) 138 (Supplement 1): 4826.
https://doi.org/10.1182/blood-2021-149180
Published: 2021