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Ismael J. Samudio, PhD
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Journal Articles

Synergistic Activation of p53 Family of Proteins by the Combination of Nutlin 3a and SAHA in Acute Myelogenous Leukemia.

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Gautam Borthakur, MD, Seshagiri Duvvuri, Ismael J. Samudio, PhD, Kensuke Kojima, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1738.
https://doi.org/10.1182/blood.V114.22.1738.1738
Published: 2009
Journal Articles

Pharmacological Inhibition of Fatty Acid Oxidation as a Novel Therapeutic Concept for Acute Myeloid Leukemia.

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Michael Andreeff, MD, PhD, Michael Fiegl, PhD, Marina Konopleva, MD, PhD, Borys Korchin, Kumar Kaluarachchi, PhD, William G. Bornmann, PhD, Patrick H. Guthrie, BS, Romain Harmancey, PhD, Heinrich Taegtmeyer, MD, PhD, Ismael J. Samudio, PhD
Journal: Blood
Blood (2009) 114 (22): 3779.
https://doi.org/10.1182/blood.V114.22.3779.3779
Published: 2009
Journal Articles

Targeting Anaplerotic Pathways That Support Fatty Acid Metabolism as a Therapeutic Strategy for Hematological Malignancies: The Achilles’ Heel of the Warburg Effect.

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Ismael J. Samudio, PhD, Michael Fiegl, PhD, Marina Konopleva, MD, PhD, Kumar Kaluarachchi, PhD, John S. McMurray, PhD, BS, Borys Korchin, Karen Clise Dwyer, PhD, Romain Harmancey, PhD, Patrick Guthrie, BS, Heinrich Taegtmeyer, MD, PhD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 1631.
https://doi.org/10.1182/blood.V112.11.1631.1631
Published: 2008
Journal Articles

Targeting the Hypoxic Microenvironment by mTOR Inhibitors Sensitizes ALL Cells to Chemotherapy

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Olga Frolova, MD, PhD, Ismael J. Samudio, PhD, Zakar H. Mnjoyan, PhD, Hongbo Lu, Sergej Konoplev, MD, PhD, Deborah A. Thomas, MD, Hagop M. Kantarjian, MD, Elizabeth J. Shpall, MD, Michael Andreeff, MD, PhD, Marina Konopleva, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 18.
https://doi.org/10.1182/blood.V112.11.18.18
Published: 2008
Journal Articles

Apoptosis Inducing Factor Acts as a Survival Factor in Acute Myelogenous Leukemia through Mitochondrial Complex 1.

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Rui-yu Wang, MD, PhD, Ismael J. Samudio, PhD, Teresa McQueen, BS, Wendy D. Schober, MLT, Vivian R. Ruvolo, Steven Kornblau, MD, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 1812.
https://doi.org/10.1182/blood.V110.11.1812.1812
Published: 2007
Journal Articles

MDM2 Inhibitor Nutlin-3a Induces p53-Dependent Apoptosis Via Transcription-Dependent and -Independent Pathways and Overcomes Fludarabine-Resistance in CLL.

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Kensuke Kojima, MD, PhD, Marina Konopleva, MD, PhD, Ismael J. Samudio, PhD, Teresa McQueen, BS, Twee Tsao, Zhihong Zeng, MD, William K. Plunkett, PhD, Michael Andreeff, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 445.
https://doi.org/10.1182/blood.V106.11.445.445
Published: 2005