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Journal Articles

Megakaryocytes Regulate Hematopoietic Stem Cell Quiescence Via PF4 Secretion

Ingmar Bruns, MD, Daniel Lucas, PhD, Sandra Pinho, PhD, Jalal Ahmed, Michele P Lambert, MD, Christoph Scheiermann, PhD, Yuya Kunisaki, MD, PhD, Mortimer Poncz, MD, Paul S. Frenette, MD

Blood (2013) 122 (21): 3.

https://doi.org/10.1182/blood.V122.21.3.3

Published: 2013

Journal Articles

Bone Marrow Arteriolar Niches Maintain Hematopoietic Stem Cell Quiescence

Yuya Kunisaki, MD, PhD, Ingmar Bruns, MD, PhD, Christoph Scheiermann, PhD, Sandra Pinho, PhD, Dachuan Zhang, Paul S. Frenette, MD, FRCPC

Blood (2012) 120 (21): 638.

https://doi.org/10.1182/blood.V120.21.638.638

Published: 2012

Journal Articles

PDGFRα and CD51 Mark Human Nestin + Sphere-Forming Mesenchymal Stem Cells Capable of Robust Hematopoietic Stem Cell Expansion

Sandra Pinho, PhD, Julie Lacombe, PhD, Maher Hanoun, MD, PhD, Ingmar Bruns, MD, PhD, Yuya Kunisaki, MD, PhD, Toshihide Mizoguchi, PhD, Paul S. Frenette, MD, FRCPC

Blood (2012) 120 (21): 505.

https://doi.org/10.1182/blood.V120.21.505.505

Published: 2012

Journal Articles

Phase II Study of Azacitidine (Vidaza®, Aza) and Donor Lymphocyte Infusions (DLI) As First Salvage Therapy in Patients with Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS) Relapsing After Allogeneic Hematopoietic Stem Cell Transplantation (allo-SCT): Final Results From the AZARELA-Trial (NCT-00795548)

Thomas Schroeder, MD, Akos Czibere, MD, PhD, Nicolaus Kröger, Uwe Platzbecker, MD, Gesine Bug, Lutz Uharek, Prof., Dr., Thomas Luft, Christine Wolschke, Ingmar Bruns, MD, Fabian Zohren, MD, Roland Fenk, Rainer Haas, MD, Prof, Guido Kobbe, MD

Blood (2011) 118 (21): 656.

https://doi.org/10.1182/blood.V118.21.656.656

Published: 2011

Journal Articles

Analysis of Mesenchymal Stromal Cells (MSC) and Their Interactions with CD34 Stem and Progenitor Cells in Patients with Myelodysplastic Syndromes (MDS)

Stefanie Geyh, Ron Patrick Cadeddu, Julia Fröbel, Ingmar Bruns, MD, Fabian Zohren, Ali-Nuri Hünerlitürkoglu, Guido Kobbe, MD, Norbert Gattermann, MD, Ulrich Germing, MD, Rainer Haas, Thomas Schroeder, MD

Blood (2011) 118 (21): 2393.

https://doi.org/10.1182/blood.V118.21.2393.2393

Published: 2011

Journal Articles

Secondary Primary Malignancies in Patients with Multiple Myeloma Treated with High-Dose Chemotherapy and Autologous Blood Stem Cell Transplantation,

Roland Fenk, MD, Florian Neubauer, Ingmar Bruns, MD, Christian Saure, MD, Thomas Schroeder, MD, Ulrich Germing, MD, Norbert Gattermann, MD, Rainer Haas, MD, Prof, Guido Kobbe, MD

Blood (2011) 118 (21): 4087.

https://doi.org/10.1182/blood.V118.21.4087.4087

Published: 2011

Journal Articles

The Disease-Related Bone Marrow Microenvironment Alters Hematopoietic Stem and Progenitor Function in Multiple Myeloma Patients

Ingmar Bruns, MD, Ron-Patrick Cadeddu, Ines Brückmann, Sebastian Buest, Julia Fröbel, Thomas Schroeder, Stefanie Geyh, Ali-Nuri Hünerlitürkoglu, Guido Kobbe, MD, Roland Fenk, Andreas Trumpp, Akos Czibere, MD, PhD, Rainer Haas

Blood (2011) 118 (21): 2898.

https://doi.org/10.1182/blood.V118.21.2898.2898

Published: 2011

Journal Articles

Natalizumab Increases Circulating CD34+ Cells with An Impaired Functional Potential In Patients with Multiple Sclerosis without Affecting the Bone Marrow.

Christian Saure, MD, Fabian Zohren, MD, Thomas Schroeder, MD, Ingmar Bruns, MD, Ron Patrick Cadeddu, Ute Fischer, MD, Guido Kobbe, MD, Hans Peter Hartung, Bernd C Kieseier, Rainer Haas

Blood (2010) 116 (21): 2620.

https://doi.org/10.1182/blood.V116.21.2620.2620

Published: 2010

Journal Articles

TIMP–1 Plays a Functional Role in CD34. + Hematopoietic Stem and Progenitor Cells.

C. Matthias Wilk, Akos G. Czibere, MD, PhD, Ron-Patrick Cadeddu, Sebastian Buest, Frank A. Schildberg, Marcel A. Lauterbach, Volker Westphal, PhD, Stefan W. Hell, Prof., Rainer Haas, Prof., Ingmar Bruns, MD, PhD

Blood (2009) 114 (22): 1487.

https://doi.org/10.1182/blood.V114.22.1487.1487

Published: 2009

Journal Articles

Malignant Myeloma Cells Impair Phenotype and Function of stem and Progenitor Cells.

Ingmar Bruns, MD, PhD, Sebastian Büst, Akos G. Czibere, MD, Ron-Patrick Cadeddu, Ines Brückmann, Manoj Bhasin, Johannes C Fischer, Roland Fenk, Guido Kobbe, MD, Andreas Trumpp, Rainer Haas

Blood (2009) 114 (22): 1799.

https://doi.org/10.1182/blood.V114.22.1799.1799

Published: 2009

Journal Articles

A Quality of Life Study Utilizing the EORTC QLQ-30 and EORTC QLQ-HDC29 Questionnaires for the Interview of 215 Patients Who Received Autologous or Allogeneic Hematopoietic Stem Cell Transplantation.

Akos G. Czibere, MD, Verena Heymann, Ingmar Bruns, MD, PhD, Thomas Schroeder, Roland Fenk, Fabian Zohren, Mustafa Kondakci, Sebastian Balleisen, Rainer Haas, Guido Kobbe, MD

Blood (2009) 114 (22): 2470.

https://doi.org/10.1182/blood.V114.22.2470.2470

Published: 2009

Journal Articles

Reapplication of High-Dose Chemotherapy and Autologous Blood Stem Cell Transplantation as Salvage Treatment for Patients with Relapsed or Refractory Multiple Myeloma – a Single Center Experience.

Roland Fenk, MD, PhD, Vanessa Liese, Ingmar Bruns, MD, PhD, Mustafa Kondakci, MD, Sebastian Balleisen, MD, Christian Saure, Thomas Schröder, MD, Rainer Haas, MD, Prof, Guido Kobbe, MD, PhD

Blood (2009) 114 (22): 3418.

https://doi.org/10.1182/blood.V114.22.3418.3418

Published: 2009

Journal Articles

Transcriptional Changes Induced by Imatinib and Nilotinib in the Chronic Myelogenous Leukemia (CML) Cell Line K562.

Daniela Bruennert, Ingmar Bruns, MD, PhD, Norbert Gattermann, Ralf Kronenwett, Rainer Haas, Frank Neumann

Blood (2009) 114 (22): 4250.

https://doi.org/10.1182/blood.V114.22.4250.4250

Published: 2009

Journal Articles

Quantitative Real-Time PCR of Peripheral Blood t(14;18) Positive Cells Predicts Treatment Response and Long-Term Outcome in Patients with Follicular Lymphoma.

Fabian Zohren, Ingmar Bruns, MD, PhD, Juergen Barth, Sabrina Pechtel, Roland Fenk, Thomas Schroeder, Akos G. Czibere, MD, Georg Maschmeyer, Dorothea Kofahl-Krause, Gerhard Heil, Norbert Niederle, Christoph Losem, Manfred Welslau, Ulrich Germing, Ralf Kronenwett, Rainer Haas, Mathias J Rummel, MD, PhD, Guido Kobbe, MD

Blood (2009) 114 (22): 441.

https://doi.org/10.1182/blood.V114.22.441.441

Published: 2009

Journal Articles

Neuropeptides Orexin A and B Are Funktionally Aktive in CD34+ Hematopoietic Stem and Progenitor Cells.

Ron-Patrick Cadeddu, Akos G. Czibere, MD, Sebastian Büst, Johannes C Fischer, Ulrich Steidl, MD, PhD, Ralf Kronenwett, Guido Kobbe, MD, Rainer Haas, Ingmar Bruns, MD, PhD

Blood (2009) 114 (22): 4593.

https://doi.org/10.1182/blood.V114.22.4593.4593

Published: 2009

Journal Articles

Platelets Derived From Patients with Myelodysplastic Syndromes (MDS) Show Defective Platelet Aggregation and Integrin aIIbβ3 Receptor (GPIIb/IIIa) Signaling Caused by a Reduced Expression of Proteins Required for Inside-out Signaling.

Akos G. Czibere, MD, Julia Fröbel, Sonja Hartwig, Ron-Patrick Cadeddu, Matthias Wilk, Ingmar Bruns, MD, PhD, Sebastian Büst, Guido Kobbe, MD, Andrea Kündgen, Jürgen Eckel, Stefan Lehr, Rainer Haas

Blood (2009) 114 (22): 598.

https://doi.org/10.1182/blood.V114.22.598.598

Published: 2009

Journal Articles

Clinical Efficacy of Sorafenib in Patients with Acute Myeloid Leukemia (AML) and Activating FLT3-Mutations.

Thomas Schroeder, MD, Christian Saure, Ingmar Bruns, MD, PhD, Fabian Zohren, Akos G. Czibere, MD, Nelly Nancy Safaian, Roland Fenk, Rainer Haas, Guido Kobbe, MD

Blood (2009) 114 (22): 2057.

https://doi.org/10.1182/blood.V114.22.2057.2057

Published: 2009

Journal Articles

The Neuropeptides Orexin a and B Have An Impact on Functional Properties of Human CD34+ Stem and Progenitor Cells.

Ingmar Bruns, MD, PhD, Patrick Cadeddu, Sebastian Büst, Boris Goerg, Johannes C Fischer, Oliver Selbach, Ulrich Steidl, MD, PhD, Ralf Kronenwett, Rainer Haas, Guido Kobbe, Akos Czibere, MD, PhD

Blood (2008) 112 (11): 1393.

https://doi.org/10.1182/blood.V112.11.1393.1393

Published: 2008

Journal Articles

Ap-1 Family Members C-Jun, JunB and Fra-2 Mediate Apoptosis and Differentiation in AML through Activation of GADD45á and ADFP Following Non-Steroidal Anti-Inflammatory Drug Treatment.

Akos Czibere, MD, PhD, Raminder Singh, PhD, Ingmar Bruns, MD, PhD, Luiz Fernando Zerbini, PhD, Rainer Haas

Blood (2008) 112 (11): 1196.

https://doi.org/10.1182/blood.V112.11.1196.1196

Published: 2008

Journal Articles

Imatinib Induced Molecular Response in CD34+ Hematopoietic Stem and Progenitor Cells of Patients with Chronic Myeloid Leukemia Following the First Week of Therapy

Daniela Bruennert, Akos Czibere, MD, PhD, Ingmar Bruns, MD, PhD, Sabrina Pechtel, Norbert Gattermann, MD, Ralf Kronenwett, Rainer Haas, Neumann Frank

Blood (2008) 112 (11): 3231.

https://doi.org/10.1182/blood.V112.11.3231.3231

Published: 2008

NARROW

Megakaryocytes Regulate Hematopoietic Stem Cell Quiescence Via PF4 Secretion

Bone Marrow Arteriolar Niches Maintain Hematopoietic Stem Cell Quiescence

PDGFRα and CD51 Mark Human Nestin + Sphere-Forming Mesenchymal Stem Cells Capable of Robust Hematopoietic Stem Cell Expansion

Analysis of Mesenchymal Stromal Cells (MSC) and Their Interactions with CD34 Stem and Progenitor Cells in Patients with Myelodysplastic Syndromes (MDS)

Secondary Primary Malignancies in Patients with Multiple Myeloma Treated with High-Dose Chemotherapy and Autologous Blood Stem Cell Transplantation,

The Disease-Related Bone Marrow Microenvironment Alters Hematopoietic Stem and Progenitor Function in Multiple Myeloma Patients

Natalizumab Increases Circulating CD34+ Cells with An Impaired Functional Potential In Patients with Multiple Sclerosis without Affecting the Bone Marrow.

TIMP–1 Plays a Functional Role in CD34. + Hematopoietic Stem and Progenitor Cells.

Malignant Myeloma Cells Impair Phenotype and Function of stem and Progenitor Cells.

A Quality of Life Study Utilizing the EORTC QLQ-30 and EORTC QLQ-HDC29 Questionnaires for the Interview of 215 Patients Who Received Autologous or Allogeneic Hematopoietic Stem Cell Transplantation.

Reapplication of High-Dose Chemotherapy and Autologous Blood Stem Cell Transplantation as Salvage Treatment for Patients with Relapsed or Refractory Multiple Myeloma – a Single Center Experience.

Transcriptional Changes Induced by Imatinib and Nilotinib in the Chronic Myelogenous Leukemia (CML) Cell Line K562.

Quantitative Real-Time PCR of Peripheral Blood t(14;18) Positive Cells Predicts Treatment Response and Long-Term Outcome in Patients with Follicular Lymphoma.

Neuropeptides Orexin A and B Are Funktionally Aktive in CD34+ Hematopoietic Stem and Progenitor Cells.

Platelets Derived From Patients with Myelodysplastic Syndromes (MDS) Show Defective Platelet Aggregation and Integrin aIIbβ3 Receptor (GPIIb/IIIa) Signaling Caused by a Reduced Expression of Proteins Required for Inside-out Signaling.

Clinical Efficacy of Sorafenib in Patients with Acute Myeloid Leukemia (AML) and Activating FLT3-Mutations.

The Neuropeptides Orexin a and B Have An Impact on Functional Properties of Human CD34+ Stem and Progenitor Cells.

Ap-1 Family Members C-Jun, JunB and Fra-2 Mediate Apoptosis and Differentiation in AML through Activation of GADD45á and ADFP Following Non-Steroidal Anti-Inflammatory Drug Treatment.

Imatinib Induced Molecular Response in CD34+ Hematopoietic Stem and Progenitor Cells of Patients with Chronic Myeloid Leukemia Following the First Week of Therapy

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American Society of Hematology

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American Society of Hematology

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