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Journal Articles

Soluble Signals Exchanged between Bone Marrow Adipocytes and Myeloma Cells Alter the Expression of Metabolic Genes in Adipocytes and Increase Pro-Survival Molecules in Myeloma Cells

Heather Fairfield, Allyson Schimelman, Michaela R Reagan
Journal: Blood
Blood (2024) 144 (Supplement 1): 6819.
https://doi.org/10.1182/blood-2024-207970
Published: 2024
Journal Articles

Multiple Myeloma Progression Is Accelerated By Microenvironmental-Derived Fatty Acid Binding Proteins 4 and 5 (FABP4/FABP5) in a Murine Model

Heather Fairfield, Haylee Duval, Kaitlyn Belknap, Katie Knox, Kehinde Abayomi, Sergey Ryzhov, Michaela R Reagan
Journal: Blood
Blood (2024) 144 (Supplement 1): 667.
https://doi.org/10.1182/blood-2024-208066
Published: 2024
Journal Articles

Fatty Acid Binding Protein 6 (FABP6) Represents a Novel Target for Multiple Myeloma

Ya-Wei Qiang, Michelle Karam, Allyson Schimelman, Edward Jachimowicz, Heather Fairfield, Michaela R Reagan
Journal: Blood
Blood (2024) 144 (Supplement 1): 4649.
https://doi.org/10.1182/blood-2024-210213
Published: 2024
Journal Articles

Investigating the Relationship between Primary Bone Marrow Adipocytes and Myeloma Cells with Three Cell Culture Systems

Heather Fairfield, Rebecca Condruti, Mariah Farrell, Reagan Di Iorio, Calvin Vary, Carlos A Gartner, Michaela R Reagan
Journal: Blood
Blood (2022) 140 (Supplement 1): 4247–4248.
https://doi.org/10.1182/blood-2022-162719
Published: 2022
Journal Articles

Fatty Acid Binding Proteins As a Novel Therapeutic Target in Multiple Myeloma

Mariah Farrell, Heather Fairfield, Anastasia D'Amico, Connor S Murphy, Carolyne Falank, Catherine R. Marinac, Sklavenitis-Pistofidis Romanos, Amanda Cao, Julie Dragon, Michaela R Reagan
Journal: Blood
Blood (2021) 138 (Supplement 1): 1569.
https://doi.org/10.1182/blood-2021-146902
Published: 2021
Journal Articles

Targeting Bone Marrow Adipose Tissue and the FABP Family Increases Efficacy of Dexamethasone in Multiple Myeloma

Mariah Farrell, BS, Heather Fairfield, MS, Connor S Murphy, BS, Anastasia D'Amico, BS
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–14.
https://doi.org/10.1182/blood-2020-142512
Published: 2020
Journal Articles

Acyl-CoA Synthetase Long Chain Family Inhibition with Triacsin C Inhibits Multiple Myeloma Cell Proliferation and Survival

Connor S Murphy, BS, Heather Fairfield, MS, Mariah Farrell, BS, Victoria DeMambro, MS, Samantha Costa, Carolyne Falank, PhD, Calvin Vary, Michaela Reagan, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10–11.
https://doi.org/10.1182/blood-2020-141994
Published: 2020
Journal Articles

Inhibition of Sialylation Impairs Adhesion on Madcam-1 and E-Selectin and Sensitize Multiple Myeloma Cells to Bortezomib in a Xenograft Mouse Model

Alessandro Natoni, PhD, Mariah Farrell, BS, Heather Fairfield, MS, Lucy Kirkham-McCarthy, MSc, Matt Macauley, PhD, Michaela Reagan, PhD, Michael E O'Dwyer, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3204.
https://doi.org/10.1182/blood-2018-99-118361
Published: 2018
Journal Articles

New Bone Cell Type Identified As Driver of Drug Resistance in Multiple Myeloma: The Bone Marrow Adipocyte

Carolyne Falank, PhD, Heather Fairfield, MS, Mariah Farrell, BS, Michaela Reagan, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 122.
https://doi.org/10.1182/blood.V130.Suppl_1.122.122
Published: 2017
Journal Articles

Myeloma-Associated Adipocytes Exhibit Reduced Adipogenic Gene Expression and Delipidation

Heather Fairfield, MS, Elizabeth J Harris, Carolyne Falank, PhD, Michaela Reagan, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1768.
https://doi.org/10.1182/blood.V130.Suppl_1.1768.1768
Published: 2017
Journal Articles

Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma

Michelle M. McDonald, Michaela R. Reagan, Scott E. Youlten, Sindhu T. Mohanty, Anja Seckinger, Rachael L. Terry, Jessica A. Pettitt, Marija K. Simic, Tegan L. Cheng, Alyson Morse, Lawrence M. T. Le, David Abi-Hanna, Ina Kramer, Carolyne Falank, Heather Fairfield, Irene M. Ghobrial, Paul A. Baldock, David G. Little, Michaela Kneissel, Karin Vanderkerken, J. H. Duncan Bassett, Graham R. Williams, Babatunde O. Oyajobi, Dirk Hose, Tri G. Phan, Peter I. Croucher
Journal: Blood
Blood (2017) 129 (26): 3452–3464.
https://doi.org/10.1182/blood-2017-03-773341
Published: 2017
Includes: Supplemental data
Journal Articles

Multiple Myeloma Progression: Dependence on Bone Marrow Adipose Tissue

Michaela Reagan, PhD, Carolyne Falank, PhD, Heather Fairfield, MS, Michelle McDonald, PhD, Peter Croucher, BSc, PhD, Clifford J. Rosen, MD
Journal: Blood
Blood (2016) 128 (22): 3262.
https://doi.org/10.1182/blood.V128.22.3262.3262
Published: 2016