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Journal Articles

PI3Kδ Inhibitor Linperlisib As a ≥ 3-Line Treatment for Relapsed or Refractory Follicular Lymphoma: A Subgroup Analysis of a Phase II, Single-Arm, Open-Label Trial

Hang Su, Tingyu Wang, Xiuhua Sun, Lihua Qiu, Junning Cao, Zhiming Li, Yuqin Song, Li Zhang, Dengju Li, Huijing Wu, Wei Zhang, Junmin Li, Keshu Zhou, Hui Zhou, Yu Yang, Zhifeng Li, Hong Cen, Zhen Cai, Zhihui Zhang, Weijun Fu, Jie Jin, IV, Fei Li, Weixin Wu, Xuekui Gu, Weiliang Zhu, Lihong Liu, Zengjun Li, Shuhua Yi, Hanying Bao, Zusheng Xu, Lugui Qiu
Journal: Blood
Blood (2023) 142 (Supplement 1): 1677.
https://doi.org/10.1182/blood-2023-178710
Published: 2023
Journal Articles

Dose Adjustments of Linperlisib in Relapsed or Refractory Follicular Lymphoma: A Post-Hoc Analysis of a Pivotal Phase II Study

Fangfang Lyu, Junning Cao, Tingyu Wang, Xiuhua Sun, Lihua Qiu, Hang Su, Zhiming Li, Yuqin Song, Li Zhang, Dengju Li, Huijing Wu, Wei Zhang, Junmin Li, Keshu Zhou, Hui Zhou, Yu Yang, Zhifeng Li, Hong Cen, Zhen Cai, Zhihui Zhang, Weijun Fu, Jie Jin, IV, Fei Li, Weixin Wu, Xuekui Gu, Weiliang Zhu, Lihong Liu, Zengjun Li, Shuhua Yi, Hanying Bao, Zusheng Xu, Lugui Qiu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6140.
https://doi.org/10.1182/blood-2023-180373
Published: 2023
Journal Articles

Subgroup Analysis from a Phase 2, Single-Arm Trial of the Oral PI3Kδ Inhibitor Linperlisib in Patients with Relapsed or Refractory Follicular Lymphoma

Tingyu Wang, Xiuhua Sun, Lihua Qiu, Hang Su, Junning Cao, Zhiming Li, Yuqin Song, Li Zhang, Dengju Li, Huijing Wu, Wei Zhang, Junmin Li, Keshu Zhou, Hui Zhou, Yu Yang, Zhifeng Li, Hong Cen, Zhen Cai, Zhihui Zhang, Weijun Fu, Jie Jin, IV, Fei Li, Weixin Wu, Xuekui Gu, Weiliang Zhu, Lihong Liu, Zengjun Li, Shuhua Yi, Hanying Bao, Zusheng Xu, Lugui Qiu
Journal: Blood
Blood (2023) 142 (Supplement 1): 6145.
https://doi.org/10.1182/blood-2023-177820
Published: 2023
Journal Articles

A Study of Linperlisib in the Treatment of Patients with Relapsed and/or Refractory Peripheral T-Cell Lymphoma

Lugui Qiu, Jie Jin, Hong Cen, Keshu Zhou, Xiaohong Xu, Fei Li, Tao Wu, Haiyan Yang, Zhen Wang, Zhiming Li, Hanying Bao, Zusheng Xu
Journal: Blood
Blood (2022) 140 (Supplement 1): 9395–9396.
https://doi.org/10.1182/blood-2022-162127
Published: 2022
Journal Articles

Single-Arm Phase 1b/2 Trial of the PI3Kδ Inhibitor Linperlisib Combining with Gemox in Relapsed and/or Refractory Diffuse Large B Cell Lymphoma

Zhiming Li, Haiyan Yang, Hong Cen, Rui Huang, Zhen Cai, Xuekui Gu, Hanying Bao, Zusheng Xu, Zuhong Xu
Journal: Blood
Blood (2021) 138 (Supplement 1): 2483.
https://doi.org/10.1182/blood-2021-150041
Published: 2021
Journal Articles

A Phase Ib Study of Linperlisib in Patients with Relapsed or Refractory Peripheral T-Cell Lymphoma

Jie Jin, Hong Cen, Keshu Zhou, Xiaohong Xu, Fei Li, Haiyan Yang, Zhiming Li, Hanying Bao, Zusheng Xu, Lugui Qiu, Yang Shu, Fei Li, Zhen Wang
Journal: Blood
Blood (2021) 138 (Supplement 1): 1386.
https://doi.org/10.1182/blood-2021-150215
Published: 2021
Journal Articles

A Phase1b Clinical Study of the Oral PI3Kδ Inhibitor, Linperlisib, in Patients with B-Cell Lymphomas

Lugui Qiu, Zhiming Li, Yunhong Huang, Ligen Liu, Lihong Liu, Ye Guo, Lan Deng, Haiyan Yang, Zhen CAI, Xu Ye, Zhen Wang, Hanying Bao, Zusheng Xu, Binghua Zheng
Journal: Blood
Blood (2021) 138 (Supplement 1): 3576.
https://doi.org/10.1182/blood-2021-148276
Published: 2021
Journal Articles

Preclinical Evaluation of MAX-40279, a FLT3/FGFR Dual Kinase Inhibitor for Treatment of Acute Myeloid Leukemia

Yuguang Wang, PhD, Hanying Bao, MD PhD, Nong Zhang, PhD, Feilan Wang, PhD, Yunsong He, MD, Tianzhi Wu, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3997.
https://doi.org/10.1182/blood-2018-99-110414
Published: 2018
Journal Articles

Preliminary Results from a Phase I, First-in-Human Study of YY-20394, a Highly Selective and Highly Potent PI3Kδ Inhibitor, in Patients with Relapsed or Refractory B-Cell Malignancies

Junyuan Qi, PhD, Yuqin Song, MD PhD, Bo Jiang, PhD, Jianyong Li, PhD, Meifeng Tu, PhD, Lingyan Ping, MD PhD, Zengjun Li, PhD, Wei Xu, MD PhD, Huayuan Zhu, MD PhD, Jun Zhu, MD PhD, Hanying Bao, MD PhD, Zusheng Xu, PhD, Lugui Qiu, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5332.
https://doi.org/10.1182/blood-2018-99-110585
Published: 2018
Journal Articles

Expression of B7-H1 in Mantle Cell Lymphoma Leads to Inhibition of T Cell Response to Tumor Cells

Lijuan Wang, MD, PhD, Jianfei Qian, PhD, Yong Lu, PhD, Haiyan Li, MD, PhD, Sungyoul Hong, PhD, Hanying Bao, MD, PhD, Donghua He, MD, PhD, Zhiqiang Liu, PhD, Yuhuan Zheng, PhD, Jin He, PhD, Yongsheng Lan, PhD, Yi Li, MD, Sattva Neelapu, MD, Jing Yang, PhD, Michael Wang, MD, Cai Zhen, MD, PhD, Qing Yi, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 2643.
https://doi.org/10.1182/blood.V118.21.2643.2643
Published: 2011
Journal Articles

Triggering of Toll-Like Receptor-4 In Human Multiple Myeloma Cells Promotes Proliferation and Alters Cell Responses to Immune and Chemotherapy Drug Attack

Zhen Cai, Hanying Bao, Peilin Lu, Lijuan Wang, Donghua He, Hanyan Li, Yang Yang, Yi Zhao, Li Yang, Yi Li, Michael Wang, Qing Yi, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 1905.
https://doi.org/10.1182/blood.V116.21.1905.1905
Published: 2010
Journal Articles

Role of TLR4 In Acute Gvhd After Allogenetic Hematopoietic Stem Cell Transplantation

Yi Zhao, Qiuyan Liu, Donghua He, Lijuan Wang, Jun Tian, Yang Yang, Peilin Lu, Hanying Bao, Yi Li, Yuanyuan Zheng, Xuetao Cao, Zhen Cai
Journal: Blood
Blood (2010) 116 (21): 2538.
https://doi.org/10.1182/blood.V116.21.2538.2538
Published: 2010
Journal Articles

Mantle Cell Lymphoma Cells Express B7 Family Molecules and B7-H1 Expression Are up-Regulated After LPS Exposure Via MEK-Dependent and PI3K/Akt-Dependent Pathways In Mantle Cell Lymphoma Cells

Lijuan Wang, Hanying Bao, Yang Yang, Yi Zhao, Donghua He, Peilin Lu, Yi Li, Li Yang, Qing Yi, MD, PhD, Michael Wang, MD, Zhen Cai
Journal: Blood
Blood (2010) 116 (21): 3114.
https://doi.org/10.1182/blood.V116.21.3114.3114
Published: 2010
Journal Articles

Triggering of Toll-Like Receptor 4 Expression in Human Multiple Myeloma Promotes Proliferation and Protects the Cells From Immune and Chemotherapy Drug Attack.

Zhen Cai, Hanying Bao, Lijuan Wang, PhD, Yang Yang, PhD, Yi Zhao, PhD, Donghua He, PhD, Peilin Lu, MD, PhD, Michael Wang, M.D.
Journal: Blood
Blood (2009) 114 (22): 2843.
https://doi.org/10.1182/blood.V114.22.2843.2843
Published: 2009
Journal Articles

Homoharringtonine Induced Apoptosis of Leukemic Cell Line MUTZ-1 Cells Is Mediated by the Endoplasmic Reticulum Stress Pathway.

Zhen Cai, MD, PhD, Jie Hu, Ph.D, Donghua He, Wenjun Wu, Liang Gao, Hanying Bao
Journal: Blood
Blood (2005) 106 (11): 4917.
https://doi.org/10.1182/blood.V106.11.4917.4917
Published: 2005
Journal Articles

HHT-Induced Cell Apoptosis Is Associated with Reduction of Survivin mRNA Expression.

Zhen Cai, PhD, MD, Hanying Bao
Journal: Blood
Blood (2004) 104 (11): 4364.
https://doi.org/10.1182/blood.V104.11.4364.4364
Published: 2004