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Journal Articles

Initial Results from the BEACON Clinical Study: A Phase 1/2 Study Evaluating the Safety and Efficacy of a Single Dose of Autologous CD34+ Base Edited Hematopoietic Stem Cells (BEAM-101) in Patients with Sickle Cell Disease with Severe Vaso-Occlusive Crises

Ashish O. Gupta, Akshay Sharma, Haydar Frangoul, Jignesh Dalal, Julie Kanter, Asif Alavi, John DiPersio, Mary Eapen, Jennifer J. Jaroscak, Ernesto Ayala, Edward D. Ziga, Stacey Rifkin-Zenenberg, Alex C. Minella, Guo Chen, Yinzhong Chen, Priya S. Chockalingam, Ling Lin, Marcelyne Joseney-Antoine, Leanne Ianniello, Beth Gardner, Adam J. Hartigan, Giuseppe Ciaramella, Sunita Goyal, Amy Simon, Alexis Thompson, Matthew M. Heeney
Journal: Blood
Blood (2024) 144 (Supplement 1): 513.
https://doi.org/10.1182/blood-2024-204888
Published: 2024
Journal Articles

A Single-Arm, Multi-Center, Retrospective Clinical Study of Cba Preconditioning Regimen for Autologous Hematopoietic Stem Cell Transplantation in Acute Leukemia

Dingjun Zhuo, Xu Tan, Guo Chen, Yingying Ma, Maihong Wang, Siyu Chen, Qin Wen, Hong Liu, Cheng Zhang, Xi Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 7120.
https://doi.org/10.1182/blood-2024-206275
Published: 2024
Journal Articles

Impact of BEAM-101 Treatment on Red Blood Cell Hemoglobin Expression, Rheology and Sickling Properties: Initial Data from the BEACON Phase 1/2 Study of Autologous CD34 + Base Edited Hematopoietic Stem Cells in Sickle Cell Disease

Priya S. Chockalingam, Ling Lin, Guo Chen, Alex C. Minella, Yinzhong Chen, Vivien Sheehan, Nan Zhang, Myriam Armant, Aliya U. Zaidi, Robert Goodrich, Patrick C. Hines, Sunita Goyal, Amy Simon
Journal: Blood
Blood (2024) 144 (Supplement 1): 4957.
https://doi.org/10.1182/blood-2024-200875
Published: 2024
Journal Articles

Combination of Olverembatinib and VP Regimen for Newly Diagnosed Adult Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Xu Tan, Guo Chen, Yingying Ma, Maihong Wang, Qin Wen, Hong Liu, Xi Zhang, Cheng Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 1449.
https://doi.org/10.1182/blood-2024-206572
Published: 2024
Journal Articles

BEAM-201 for the Treatment of Relapsed and/or Refractory (R/R) T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LL): Initial Data from the Phase (Ph) 1/2 Dose-Exploration, Dose-Expansion, Safety, and Efficacy Study of Multiplex Base-Edited Allogeneic Anti-CD7 CAR-T-Cells

Caroline Diorio, Paul Shaughnessy, Nosha Farhadfar, Anjali S. Advani, Wen-Kai Weng, Hagop Youssoufian, Guo Chen, Felicia Nguyen Brown, Bahru Habtermariam, Lalit Kumar, Jigar Patel, Shangbin (Gary) Liu, Sunita Goyal, Amy Simon, Alex C. Minella, David T. Teachey
Journal: Blood
Blood (2024) 144 (Supplement 1): 4838.
https://doi.org/10.1182/blood-2024-203546
Published: 2024
Journal Articles

Venetoclax, Azacitidine, Combined with Low-Dose Cytarabine in Older Newly Diagnosed Acute Myeloid Leukemia：the Result of a Prospective, Multicenter, Open, Randomized Controlled Trials

Xiao Han, Hai Yi, Hongju Yan, Ying Zhang, Yun Luo, Yue Xiao, Mengyun Zhang, Liang Fang, Guo Chen, Zhiyuan Peng, Kai Wan, Xu Tan, Xiannian Qin, Maihong Wang, Siyu Chen, Yingying Ma, Hong Liu, Cheng Zhang, Qin Wen, Xi Zhang
Journal: Blood
Blood (2024) 144 (Supplement 1): 2902.
https://doi.org/10.1182/blood-2024-206513
Published: 2024