1-10 of 10
Greg Coffey, PhD
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

A Phase I Open-Label, Multi-Dose Escalation Study of the Dual Syk/Jak Inhibitor PRT062070 (Cerdulatinib) in Patients with Relapsed/Refractory B Cell Malignancies

Manish Patel, Paul Hamlin, MD, Donald K Strickland, MD, Anjali Pandey, PhD, Greg Coffey, PhD, Janet M Leeds, PhD, Gallia G. Levy, MD PhD, John T. Curnutte, MDPhD, Nina Wagner-Johnston, Ian W. Flinn, MD
Journal: Blood
Blood (2014) 124 (21): 3103.
https://doi.org/10.1182/blood.V124.21.3103.3103
Published: 2014
Journal Articles

Immunoglobulin Heavy Chain (IgH) Knockout Inhibits Proliferation of Pre-BCR + B-Cell Acute Lymphoblastic Leukemia (B-ALL) Via a FOXO1 and MYC Dependent Mechanism

Stefan Koehrer, MD, Ondrej Havranek, MDPhD, R Eric Davis, MD, Felix Seyfried, MD, Greg Coffey, PhD, Ekaterina Kim, MS, Nathalie Y. Rosin, PhD, Elisa ten Hacken, PhD, Ulrich Jäger, MD, Katrina Vanura, PhD, Susan O'Brien, MD, Deborah A. Thomas, MD, Hagop M. Kantarjian, MD, Dipanjan Ghosh, PhD, Zhiqiang Wang, Lüder Hinrich Meyer, MD, Hassan Jumaa, PhD, Jan A. Burger, MDPhD
Journal: Blood
Blood (2014) 124 (21): 287.
https://doi.org/10.1182/blood.V124.21.287.287
Published: 2014
Journal Articles

SYK and STAT3 Are Active in Diffuse Large B-Cell Lymphoma: Activity of Cerdulatinib, a Dual SYK/JAK Inhibitor

Y. Lynn Wang, MD PhD, Jiao Ma, PhD, Wei Xing, PhD, Pin Lu, MD PhD, Karen Dresser, Ailin Guo, PhDMD, Anjali Pandey, PhD, Pamela B. Conley, PhD, Hongbo Yu, MD PhD, Greg Coffey, PhD
Journal: Blood
Blood (2014) 124 (21): 926.
https://doi.org/10.1182/blood.V124.21.926.926
Published: 2014
Journal Articles

Dual SYK/JAK Inhibition Has a Broader Anti-Tumor Activity In Both ABC and GCB Types Of Diffuse Large B Cell Lymphoma

Jiao Ma, PhD, Greg Coffey, PhD, Pin Lu, MD, PhD, Shuhua Cheng, PhD, Ailin Guo, MD, PhD, Anjali Pandey, PhD, Y. Lynn Wang, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1833.
https://doi.org/10.1182/blood.V122.21.1833.1833
Published: 2013
Journal Articles

Pre-BCR Signaling Activity Predicts Sensitivity To Syk Kinase Inhibition In B Cell Acute Lymphoblastic Leukemia (B-ALL)

Stefan Koehrer, MD, Richard E. Davis, M.D., Greg Coffey, PhD, Ekaterina Kim, MS, Nathalie Y. Rosin, PhD, Elisa ten Hacken, Susan O'Brien, MD, William G. Wierda, MD, PhD, Zeev Estrov, MD, Deborah A. Thomas, MD, Hagop M. Kantarjian, MD, Zhiqiang Wang, Ph.D., Hassan Jumaa, PhD, Jan A. Burger, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 614.
https://doi.org/10.1182/blood.V122.21.614.614
Published: 2013
Journal Articles

Efficacy of PRT060318, a Novel Highly Specific SYK Inhibitor, in Acute Lymphoblastic Leukemia (ALL)

Stefan KÖhrer, MD, Greg Coffey, PhD, Ekaterina Kim, MS, Nathalie Y Rosin, PhD, Uma Sinha, PhD, Anjali Pandey, PhD, Medhat Shehata, Ulrich Jäger, Susan M. O'Brien, MD, William G. Wierda, MD, Ph.D., Zeev Estrov, MD, PhD, Deborah Thomas, MD, Hagop M Kantarjian, Jan A. Burger, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3532.
https://doi.org/10.1182/blood.V120.21.3532.3532
Published: 2012
Journal Articles

PRT062070: A Dual Syk/JAK Inhibitor with Potent Immune Regulatory Capacity in Rodent Models of Inflammation and Cancer.

Greg Coffey, PhD, Francis DeGuzman, PhD, Gail Lee, BS, Lynn Kamen, PhD, Dale Baker, PhD, Stanley J Hollenbach, BS, JD, Anjali Pandey, PhD, Uma Sinha, PhD
Journal: Blood
Blood (2012) 120 (21): 2764.
https://doi.org/10.1182/blood.V120.21.2764.2764
Published: 2012
Journal Articles

Highly Specific Inhibitor for Syk Induces Chronic Lymphocytic Leukemia Cell Apoptosis,

Liguang Chen, MD, PhD, George Chen, B.S., Jessie-Farah Fecteau, Ph.D., Greg Coffey, PhD, Charles Prussak, PhD, Dennis A. Carson, MD, Thomas Kipps, MD
Journal: Blood
Blood (2011) 118 (21): 3875.
https://doi.org/10.1182/blood.V118.21.3875.3875
Published: 2011
Journal Articles

Spleen Tyrosine Kinase (Syk) Inhibitors Block B Cell Receptor Signaling and Survival In Chronic Lymphocytic Leukemia

Julia Hoellenriegel, Greg Coffey, PhD, Uma Sinha, PhD, Anjali Pandey, PhD, William G. Wierda, MD, PhD, Michael J Keating, MD, Jan A. Burger, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3604.
https://doi.org/10.1182/blood.V116.21.3604.3604
Published: 2010
Journal Articles

Specific Inhibition of Syk Suppresses Leukocyte Immune Function and Alleviates Inflammation In Rodent Models of Rheumatoid Arthritis

Greg Coffey, PhD, DeGuzman Francis, Ph.D., Mayuko Inagaki, Yvonne Pak, Suzanne Delaney, Andreas Betz, Zhaozhong J Jia, Qing Xu, Shawn Bauer, Yonghong Song, Anjali Pandey, PhD, Dale Baker, DVM, PhD, Stanley Hollenbach, David R. Phillips, PhD, Uma Sinha, PhD
Journal: Blood
Blood (2010) 116 (21): 1727.
https://doi.org/10.1182/blood.V116.21.1727.1727
Published: 2010