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Journal Articles

Complement mediates binding and procoagulant effects of ultralarge HIT immune complexes

Sanjay Khandelwal, Ayiesha Barnes, Lubica Rauova, Amrita Sarkar, Ann H. Rux, Serge V. Yarovoi, S. Sergei Zaitsev, John D. Lambris, Sooho S. Myoung, Alexandra Johnson, Grace M. Lee, Madelaine Duarte, Mortimer Poncz, Gowthami M. Arepally, Douglas B. Cines

Blood (2021) 138 (21): 2106–2116.

https://doi.org/10.1182/blood.2020009487

Published: 2021

Includes: Supplemental data

Journal Articles

Neutrophil Phenotypes Result in Differential Responses to Pathogens

Stacey A Maskarinec, Halie Hotchkiss, Madelaine Duarte, Margaret McKelvy, Bechtler Addison, Gowthami M. Arepally, Grace M Lee

Blood (2021) 138 (Supplement 1): 988.

https://doi.org/10.1182/blood-2021-153070

Published: 2021

Journal Articles

Minimal Role for the Alternative Pathway in Complement Activation By HIT Immune Complexes

Ayiesha Barnes, Sanjay Khandelwal, Simone Sartoretto, Grace M Lee, Sooho Myoung, Samuel Francis, Lubica Rauova, Douglas B. Cines, Brandon Garcia, Jon Skare, Charles Booth, Gowthami M. Arepally

Blood (2021) 138 (Supplement 1): 2076.

https://doi.org/10.1182/blood-2021-150946

Published: 2021

Journal Articles

Can HIT testing lose its radioactivity?

Grace M. Lee

Blood (2021) 137 (8): 1008–1010.

https://doi.org/10.1182/blood.2020008908

Published: 2021

Journal Articles

Complement Regulates the Procoagulant Effects of HIT Immune Complexes

Sanjay Khandelwal, PhD, Lubica Rauova, MD PhD, Ayiesha Barnes, MS, Ann Rux, Serge Yarovoi, Sooho S Myoung, Alexandra Johnson, Grace M Lee, MD, Madelaine Duarte, BA, Mortimer Poncz, MD, Gowthami M. Arepally, MD, Douglas B. Cines, MD

Blood (2020) 136 (Supplement 1): 11–12.

https://doi.org/10.1182/blood-2020-138631

Published: 2020

Journal Articles

Variation in Neutrophil Function Among Healthy Subjects Influences Response to Bacteria

Madelaine Duarte, BA, Stacey A Maskarinec, MD PhD, Sanjay Khandelwal, PhD, Gowthami M. Arepally, MD, Grace M Lee, MD

Blood (2020) 136 (Supplement 1): 34.

https://doi.org/10.1182/blood-2020-141674

Published: 2020

Journal Articles

Polyreactive IgM initiates complement activation by PF4/heparin complexes through the classical pathway

Sanjay Khandelwal, Joann Ravi, Lubica Rauova, Alexandra Johnson, Grace M. Lee, Jennifer B. Gilner, Sreenivasulu Gunti, Abner L. Notkins, Maragatha Kuchibhatla, Michael Frank, Mortimer Poncz, Douglas B. Cines, Gowthami M. Arepally

Blood (2018) 132 (23): 2431–2440.

https://doi.org/10.1182/blood-2018-03-834598

Published: 2018

Includes: Supplemental data

Journal Articles

Novel ELISA-Based Assay for Detection of Complement Activation By PF4/Heparin Complexes

Sanjay Khandelwal, PhD, Johnson M Alexandra, BS, Grace M. Lee, MD, Gowthami M Arepally, MD

Blood (2016) 128 (22): 3734.

https://doi.org/10.1182/blood.V128.22.3734.3734

Published: 2016

Journal Articles

The antigenic complex in HIT binds to B cells via complement and complement receptor 2 (CD21)

Sanjay Khandelwal, Grace M. Lee, C. Garren Hester, Mortimer Poncz, Steven E. McKenzie, Bruce S. Sachais, Lubica Rauova, Garnett Kelsoe, Douglas B. Cines, Michael Frank, Gowthami M. Arepally

Blood (2016) 128 (14): 1789–1799.

https://doi.org/10.1182/blood-2016-04-709634

Published: 2016

Includes: Supplemental data

Journal Articles

Characterization of Human and Murine Anti-Protamine/Heparin Antibodies

Grace M. Lee, MD, Manali Joglekar, MS, Sanjay Khandelwal, Rui Qi, BS, Lubica Rauova, MD PhD, Gowthami M Arepally, MD

Blood (2015) 126 (23): 3461.

https://doi.org/10.1182/blood.V126.23.3461.3461

Published: 2015

Journal Articles

Biologic Activities of Protamine/Heparin Antibodies

Grace M. Lee, MD, Manali V. Joglekar, Rui Qi, Gowthami M Arepally, MD

Blood (2014) 124 (21): 2784.

https://doi.org/10.1182/blood.V124.21.2784.2784

Published: 2014

Journal Articles

High incidence of antibodies to protamine and protamine/heparin complexes in patients undergoing cardiopulmonary bypass

Grace M. Lee, Ian J. Welsby, Barbara Phillips-Bute, Thomas L. Ortel, Gowthami M. Arepally

Blood (2013) 121 (15): 2828–2835.

https://doi.org/10.1182/blood-2012-11-469130

Published: 2013

Includes: Supplemental data

Journal Articles

High Incidence of Antibodies to Protamine and Protamine/Heparin Complexes in Patients Undergoing Cardiopulmonary Bypass

Grace M. Lee, MD, Ian Welsby, MBBS, Barbara Phillips Bute, PhD, Thomas L. Ortel, MD, PhD, Gowthami M Arepally, MD

Blood (2012) 120 (21): 3344.

https://doi.org/10.1182/blood.V120.21.3344.3344

Published: 2012

NARROW

Complement mediates binding and procoagulant effects of ultralarge HIT immune complexes

Neutrophil Phenotypes Result in Differential Responses to Pathogens

Minimal Role for the Alternative Pathway in Complement Activation By HIT Immune Complexes

Can HIT testing lose its radioactivity?

Complement Regulates the Procoagulant Effects of HIT Immune Complexes

Variation in Neutrophil Function Among Healthy Subjects Influences Response to Bacteria

Polyreactive IgM initiates complement activation by PF4/heparin complexes through the classical pathway

Novel ELISA-Based Assay for Detection of Complement Activation By PF4/Heparin Complexes

The antigenic complex in HIT binds to B cells via complement and complement receptor 2 (CD21)

Characterization of Human and Murine Anti-Protamine/Heparin Antibodies

Biologic Activities of Protamine/Heparin Antibodies

High incidence of antibodies to protamine and protamine/heparin complexes in patients undergoing cardiopulmonary bypass

High Incidence of Antibodies to Protamine and Protamine/Heparin Complexes in Patients Undergoing Cardiopulmonary Bypass

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American Society of Hematology

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ASH Publications

American Society of Hematology

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