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Journal Articles

Variation in Neutrophil Function Among Healthy Subjects Influences Response to Bacteria

Madelaine Duarte, BA, Stacey A Maskarinec, MD PhD, Sanjay Khandelwal, PhD, Gowthami M. Arepally, MD, Grace M Lee, MD

Blood (2020) 136 (Supplement 1): 34.

https://doi.org/10.1182/blood-2020-141674

Published: 2020

Journal Articles

Complement Regulates the Procoagulant Effects of HIT Immune Complexes

Sanjay Khandelwal, PhD, Lubica Rauova, MD PhD, Ayiesha Barnes, MS, Ann Rux, Serge Yarovoi, Sooho S Myoung, Alexandra Johnson, Grace M Lee, MD, Madelaine Duarte, BA, Mortimer Poncz, MD, Gowthami M. Arepally, MD, Douglas B. Cines, MD

Blood (2020) 136 (Supplement 1): 11–12.

https://doi.org/10.1182/blood-2020-138631

Published: 2020

Journal Articles

Mechanism of Complement Activation By PF4/ Heparin Complexes

Sanjay Khandelwal, PhD, Johnson M Alexandra, BS, C. Garren Hester, Michael M Frank, MD, Gowthami M Arepally, MD

Blood (2016) 128 (22): 137.

https://doi.org/10.1182/blood.V128.22.137.137

Published: 2016

Journal Articles

Novel ELISA-Based Assay for Detection of Complement Activation By PF4/Heparin Complexes

Sanjay Khandelwal, PhD, Johnson M Alexandra, BS, Grace M. Lee, MD, Gowthami M Arepally, MD

Blood (2016) 128 (22): 3734.

https://doi.org/10.1182/blood.V128.22.3734.3734

Published: 2016

Journal Articles

RNA Aptamer Against FXa Synergizes with FXa Catalytic Site Inhibitors to Effectively and Reversibly Anticoagulate Blood in an Ex Vivo Oxygenator Circuit

Ruwan Gunaratne, MA, James Frederiksen, MD, Nabil K. Thalji, BS, Michelle D Ho, Gowthami M Arepally, MD, Rodney M. Camire, PhD, Bruce A. Sullenger, PhD

Blood (2016) 128 (22): 3823.

https://doi.org/10.1182/blood.V128.22.3823.3823

Published: 2016

Journal Articles

Thrombocytopenia in Hospitalized Non-ICU Patients

Eric Fountain, MD MA, Gowthami M Arepally, MD

Blood (2015) 126 (23): 1060.

https://doi.org/10.1182/blood.V126.23.1060.1060

Published: 2015

Journal Articles

The Thrombotic Microangiopathy Registry of North America

Ara Metjian, MD, Yvette Tanhehco, MD, Huy Phu Pham, MD, M.P.H., Nicole A. Aqui, MD, Vijay Bhoj, MD PhD, Oluwatoyosi Onwuemene, MD, Marisa Marques, MD, Gowthami M Arepally, MD

Blood (2015) 126 (23): 5587.

https://doi.org/10.1182/blood.V126.23.5587.5587

Published: 2015

Journal Articles

Characterization of Human and Murine Anti-Protamine/Heparin Antibodies

Grace M. Lee, MD, Manali Joglekar, MS, Sanjay Khandelwal, Rui Qi, BS, Lubica Rauova, MD PhD, Gowthami M Arepally, MD

Blood (2015) 126 (23): 3461.

https://doi.org/10.1182/blood.V126.23.3461.3461

Published: 2015

Journal Articles

Atomic Level Description of the Immune Complex That Causes Heparin-Induced Thrombocytopenia (HIT)

Zheng Cai, PhD, Serge V. Yarovoi, PhD, Zhiquiang Zhu, PhD, Lubica Rauova, MD,PhD, Tatiana Lebedeva, PhD, Mortimer Poncz, MD, Gowthami M Arepally, MD, Douglas B. Cines, MD, Mark I. Greene, MD

Blood (2014) 124 (21): 465.

https://doi.org/10.1182/blood.V124.21.465.465

Published: 2014

Journal Articles

Biologic Activities of Protamine/Heparin Antibodies

Grace M. Lee, MD, Manali V. Joglekar, Rui Qi, Gowthami M Arepally, MD

Blood (2014) 124 (21): 2784.

https://doi.org/10.1182/blood.V124.21.2784.2784

Published: 2014

Journal Articles

Predicting the Temporal Course of Laboratory Abnormality Resolution in Patients with Thrombotic Microangiopathy

Allyson Marie Pishko, MD, Gowthami M Arepally, MD

Blood (2014) 124 (21): 4192.

https://doi.org/10.1182/blood.V124.21.4192.4192

Published: 2014

Journal Articles

Understanding the Underlying Immune Response in HIT: Uptake of PF4/Heparin Complexes By Monocytes & Dendritic Cells

Manali V. Joglekar, Sanjay Khandelwal, Mortimer Poncz, MD, Lubica Rauova, MD PhD, Gowthami M Arepally, MD

Blood (2014) 124 (21): 4197.

https://doi.org/10.1182/blood.V124.21.4197.4197

Published: 2014

Journal Articles

PF4/H Complexes Induce Germinal Centers in Vivo

Manali Joglekar, Rui Qi, Gowthami M. Arepally, MD

Blood (2012) 120 (21): 269.

https://doi.org/10.1182/blood.V120.21.269.269

Published: 2012

Journal Articles

High Incidence of Antibodies to Protamine and Protamine/Heparin Complexes in Patients Undergoing Cardiopulmonary Bypass

Grace M. Lee, MD, Ian Welsby, MBBS, Barbara Phillips Bute, PhD, Thomas L. Ortel, MD, PhD, Gowthami M Arepally, MD

Blood (2012) 120 (21): 3344.

https://doi.org/10.1182/blood.V120.21.3344.3344

Published: 2012

Journal Articles

Novel Techniques for Measurement of Variable Sized PF4/H Complexes.

Benjamin Espinasse, Manali Joglekar, Giancarlo Valiente, Gowthami M. Arepally, MD

Blood (2012) 120 (21): 2204.

https://doi.org/10.1182/blood.V120.21.2204.2204

Published: 2012

Journal Articles

Critical Role for Mouse Marginal Zone B Cells in PF4/Heparin Antibody Production

Yongwei Zheng, Mei Yu, Andrew Podd, Debra K. Newman, PhD, Renren Wen, Gowthami M Arepally, MD, Demin Wang

Blood (2012) 120 (21): 1175.

https://doi.org/10.1182/blood.V120.21.1175.1175

Published: 2012

Journal Articles

Novel Diagnostic Assays for Heparin-Induced Thrombocytopenia

Adam Cuker, MD, MS, Ann H Rux, PhD, Jillian L Hinds, BS, May Dela Cruz, MD, Serge Yarovoi, PhD, Wei Yang, PhD, Barbara A. Konkle, MD, Gowthami M Arepally, MD, Steve P Watson, PhD, Douglas B. Cines, Bruce S Sachais, MD, PhD

Blood (2012) 120 (21): 267.

https://doi.org/10.1182/blood.V120.21.267.267

Published: 2012

Journal Articles

HIT Antibody Seropositivity and Thromboembolic Events After Cardiac Surgery

Thomas L. Ortel, MD, PhD, Ian Welsby, MD, David F Kong, MD, John A. Heit, M.D., Elizabeth Krakow, MD, Nicole Whitlatch, MD, Gowthami M. Arepally, MD, Grace Lee, MD, Shahar Bar-Yosef, MD, Eliot C. Williams, MD, PhD

Blood (2011) 118 (21): 1159.

https://doi.org/10.1182/blood.V118.21.1159.1159

Published: 2011

Journal Articles

Heparin Modifies the Immunogenicity of Positively-Charged Proteins.

Gowthami M. Arepally, MD, Shalini Chudasama, Benjamin Espinasse, Fred Hwang, Rui Qi, Manali Joglekar, Galyna Afonina, Mark Wiesner, Ian Welsby, Thomas Ortel

Blood (2010) 116 (21): 1435.

https://doi.org/10.1182/blood.V116.21.1435.1435

Published: 2010

Journal Articles

Dendritic Cell Activation by PF4/H Multimolecular Complexes

Galyna Afonina, Manali Joglekar, Rui Qi, Gowthami M. Arepally, MD

Blood (2010) 116 (21): 722.

https://doi.org/10.1182/blood.V116.21.722.722

Published: 2010

NARROW

Variation in Neutrophil Function Among Healthy Subjects Influences Response to Bacteria

Complement Regulates the Procoagulant Effects of HIT Immune Complexes

Mechanism of Complement Activation By PF4/ Heparin Complexes

Novel ELISA-Based Assay for Detection of Complement Activation By PF4/Heparin Complexes

RNA Aptamer Against FXa Synergizes with FXa Catalytic Site Inhibitors to Effectively and Reversibly Anticoagulate Blood in an Ex Vivo Oxygenator Circuit

Thrombocytopenia in Hospitalized Non-ICU Patients

The Thrombotic Microangiopathy Registry of North America

Characterization of Human and Murine Anti-Protamine/Heparin Antibodies

Atomic Level Description of the Immune Complex That Causes Heparin-Induced Thrombocytopenia (HIT)

Biologic Activities of Protamine/Heparin Antibodies

Predicting the Temporal Course of Laboratory Abnormality Resolution in Patients with Thrombotic Microangiopathy

Understanding the Underlying Immune Response in HIT: Uptake of PF4/Heparin Complexes By Monocytes & Dendritic Cells

PF4/H Complexes Induce Germinal Centers in Vivo

High Incidence of Antibodies to Protamine and Protamine/Heparin Complexes in Patients Undergoing Cardiopulmonary Bypass

Novel Techniques for Measurement of Variable Sized PF4/H Complexes.

Critical Role for Mouse Marginal Zone B Cells in PF4/Heparin Antibody Production

Novel Diagnostic Assays for Heparin-Induced Thrombocytopenia

HIT Antibody Seropositivity and Thromboembolic Events After Cardiac Surgery

Heparin Modifies the Immunogenicity of Positively-Charged Proteins.

Dendritic Cell Activation by PF4/H Multimolecular Complexes

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American Society of Hematology

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