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Frederick Chen
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Journal Articles

Part a Efficacy and Safety of Oral Bruton Tyrosine Kinase Inhibitor (BTKi) Rilzabrutinib in Patients with Warm Autoimmune Hemolytic Anemia (wAIHA): Multicenter, Open-Label, Phase 2b Study

Nichola Cooper, David J Kuter, Henrik Frederiksen, Bing Han, Frederick Chen, Wilma Barcellini, Joan Cid, Catherine M. Broome, Míriam Vara, Amitabha Mazumder, Alessandro Lucchesi, Xin Zhao, Antonio M Risitano, Sumit Sawhney, Quentin A. Hill, Deepthi Jayawardene, Remco Diab, Jing Zhao, Ahmed Daak
Journal: Blood
Blood (2024) 144 (Supplement 1): 3836.
https://doi.org/10.1182/blood-2024-200325
Published: 2024
Journal Articles

Autoimmune hemolytic anemia during pregnancy and puerperium: an international multicenter experience

CME Clinical Trials & Observations Brief Report
Bruno Fattizzo, Marta Bortolotti, Norma N. Fantini, Andreas Glenthøj, Marc Michel, Mariasanta Napolitano, Simona Raso, Frederick Chen, Vickie McDonald, Irina Murakhovskaya, Josephine Mathilde Iris Vos, Andrea Patriarca, Maria Eva Mingot-Castellano, Giulio Giordano, Margherita Scarrone, Tomás José González-López, Laura Trespidi, Daniele Prati, Wilma Barcellini
Journal: Blood
Blood (2023) 141 (16): 2016–2021.
https://doi.org/10.1182/blood.2022018890
Published: 2023
Includes: Supplemental data
Journal Articles

Autoimmune Hemolytic Anemia during Pregnancy or Post-Partum: An International Multi-Center Experience

Marta Bortolotti, Norma Fantini, Andreas Glenthøj, Marc Michel, Mariasanta Napolitano, Simona Raso, Frederick Chen, Vickie McDonald, Irina Murakhovskaya, Josephine M.I. Vos, Andrea Patriarca, Maria Eva Mingot, Giulio Giordano, Margherita Scarrone, Laura Trespidi, Daniele Prati, Wilma Barcellini, Bruno Fattizzo
Journal: Blood
Blood (2022) 140 (Supplement 1): 2440–2442.
https://doi.org/10.1182/blood-2022-156656
Published: 2022
Journal Articles

Thrombopoietin receptor agonists in adult Evans syndrome: an international multicenter experience

Clinical Trials & Observations
Bruno Fattizzo, Nicola Cecchi, Marta Bortolotti, Giulio Giordano, Andrea Patriarca, Andreas Glenthøj, Silvia Cantoni, Marco Capecchi, Frederick Chen, Maria Eva Mingot-Castellano, Mariasanta Napolitano, Henrik Frederiksen, Tomàs José Gonzaléz-Lopez, Wilma Barcellini
Journal: Blood
Blood (2022) 140 (7): 789–792.
https://doi.org/10.1182/blood.2022016818
Published: 2022
Journal Articles

Efficacy of Thrombopoietin Receptor Agonists in Evans Syndrome: An International Multicenter Experience

Nicola Cecchi, Juri Alessandro Giannotta, Andrea Patriarca, Andreas Glenthøj, Maria Eva Mingot, Frederick Chen, Silvia Cantoni, Dennis Lund Hansen, Marco Capecchi, Henrik Frederiksen, Tomas Jose Gonzalez-Lopez, Wilma Barcellini, Bruno Fattizzo
Journal: Blood
Blood (2021) 138 (Supplement 1): 3155.
https://doi.org/10.1182/blood-2021-149383
Published: 2021
Journal Articles

Evans' Syndrome in Adults: An Observational Multicentre Study

Bruno Fattizzo, MD, Marc Michel, Juri Alessandro Giannotta, MD, Dennis Lund Hansen, Montserrat Lopez Rubio, PhD, Emanuele Sutto, MD, Nicola Bianchetti, MD, Andrea Patriarca, MD, Silvia Cantoni, Maria Eva Mingot-Castellano, PhD MD, Vickie McDonald, MD, Marco Capecchi, MD, Josephine M.I Vos, Paola Bianchi, BSc, PhD, Nicola Vianelli, MD, Frederick Chen, MD, Henrik Frederiksen, MD PhD Prof, Tomas Jose Gonzalez-Lopez, Wilma Barcellini
Journal: Blood
Blood (2020) 136 (Supplement 1): 27–28.
https://doi.org/10.1182/blood-2020-136900
Published: 2020
Journal Articles

A Phase Ib Study to Assess the Safety and Tolerability of Ruxolitinib in Combination with Azacitidine in Patients with Advanced Phase Myeloproliferative Neoplasms (MPN), Including Myelodysplastic Syndromes (MDS) or Acute Myeloid Leukaemia (AML) Arising from MPN (The Bloodwise / TAP PHAZAR Study on Behalf of the UK MPN CSG)

Mark W Drummond, MB ChB, PhD FRCPath, Claire N. Harrison, BMBCh, DM, FRCP, FRCPath, Samuel Munoz Vicente, MSc, Adam J Mead, MD PhD, Christina Yap, MSci, PhD CStat, Frederick Chen, FRCP, FRCPath, PhD, Srinivasan Narayanan, MBBS, MRCP, FRCPath, Dragana Milojkovic, MBBS, PhD, Leyre Navarro-Nunez, PhD, Steven Knapper, BMBCh, MRCP, MRCPath, DM
Journal: Blood
Blood (2017) 130 (Supplement 1): 1649.
https://doi.org/10.1182/blood.V130.Suppl_1.1649.1649
Published: 2017
Journal Articles

Ruxolitinib vs best available therapy for ET intolerant or resistant to hydroxycarbamide

Clinical Trials & Observations
Claire N. Harrison, Adam J. Mead, Anesh Panchal, Sonia Fox, Christina Yap, Emmanouela Gbandi, Aimee Houlton, Samah Alimam, Joanne Ewing, Marion Wood, Frederick Chen, Jason Coppell, Nicki Panoskaltsis, Steven Knapper, Sahra Ali, Angela Hamblin, Robyn Scherber, Amylou C. Dueck, Nicholas C. P. Cross, Ruben Mesa, Mary Frances McMullin
Journal: Blood
Blood (2017) 130 (17): 1889–1897.
https://doi.org/10.1182/blood-2017-05-785790
Published: 2017
Includes: Supplemental data
Journal Articles

Patients with Splanchnic Vein Thrombosis Demonstrate Significantly Increased Platelet Activity

Anicee Danaee, Keith Gomez, MBBS, PhD FRCPath, Mike Laffan, MBBS, FRCP, FRCPath, PhD, David w PATCH, MBBS, FRCP, Khalid Saja, MBBS, FRCPath, Frederick Chen, MBBS, PhD FRCPath, Mallika Sekhar, MBBS, MD FRCPath, FRCP
Journal: Blood
Blood (2016) 128 (22): 1430.
https://doi.org/10.1182/blood.V128.22.1430.1430
Published: 2016
Journal Articles

Correlation Between Treatment Outcomes, Baseline Characteristics and Molecular Responses in the Majic Study Which Compared Ruxolitinib to Best Available Therapy in Essential Thrombocythemia

Claire N. Harrison, DM, FRCP, FRCPath, Adam Mead, MD PhD, Sonia Fox, Anesh Panchal, BSc, MSc, Christina Yap, BSc, MSc, PhD, Aimee E Houlton, BSc, MSc, Samah Aliman, Joanne C Ewing, PhD BMBS, BSc, FRPATH,, Marion Wood, FRCP, FRCPath, Frederick Chen, MBBS, PhD FRCPath, Jason Coppell, Nicki Panoskaltsis, MD PhD, Steven Knapper, Sahra Ali, FRCPath, Angela Hamblin, MDPhD, Robyn M. Scherber, MD MPH, Holly Geyer, MD, Allison H Scotch, MD MPH, Amylou Constance Dueck, PhD, Nicholas CP Cross, PhD, Ruben A. Mesa, MD, Mary Frances McMullin, MD
Journal: Blood
Blood (2016) 128 (22): 1929.
https://doi.org/10.1182/blood.V128.22.1929.1929
Published: 2016
Journal Articles

Differentiated Human CD8 + Memory T Cells Can Revert to a Naive-like Phenotype with Memory Stem Cell Functions.

Guido Frumento, Andrea White, Stephen Kissane, Zsuzsanna Nagy, Steven Lee, Graham Anderson, Paul Moss, Frederick Chen
Journal: Blood
Blood (2015) 126 (23): 5429.
https://doi.org/10.1182/blood.V126.23.5429.5429
Published: 2015
Journal Articles

TNFR2 Is Expressed Preferentially By Late Differentiated CD8 T-Cells and Can be Triggered By TNFR2-Specific Ligand to Induce Cell Death of Recently Activated Antigen-Specific T Cells: A Possible Role of TNFR2 in T-Cell Deflation

Mohammad Raeiszadeh, MPhil, Matthew Verney, MSc, Charles Craddock, MDPhD, Harald Wajant, PhD, Paul Moss, MDPhD, Frederick Chen, MDPhD
Journal: Blood
Blood (2014) 124 (21): 4352.
https://doi.org/10.1182/blood.V124.21.4352.4352
Published: 2014
Journal Articles

Splanchnic Vein Thrombosis Associated with Myeloproliferative Neoplasms: A Study of the AGIMM & IWG-MRT Groups in 519 Subjects

Lisa Pieri, MDPhD, Paola Guglielmelli, MD PhD, Massimo Primignani, MD, Silvia Betti, MD, Maria Luigia Randi, MD, Elisa Rumi, MD, Cristiana Pascutto, PhD, Francisco Cervantes, MD PhD, Martin Ellis, MD, Frederick Chen, MDPhD, Federica Delaini, BiolSC, Claire N Harrison, DM, FRCP, FRCPath, Giorgina Specchia, MD, Heinz Gisslinger, MD, Nicola Vianelli, MD, Marco Ruggeri, MD, Francois Girodon, MD PhD, Alberto Bosi, MD, Claudia Santarossa, MD, Alessandra Carobbio, MSc, Maya Koren-Michowitz, MD, Noa Lavi, MD, Dhiraj Tripathi, MD, Neil Rajoriya, MD, Ravi Gupta, MD, Elena Rossi, MD, Natalia Curto Garcia, MD, Alessandra Ricco, MD, Bettina Gisslinger, MD, Nicola Polverelli, MD, Mario Cazzola, MD, Valerio De Stefano, MD, Tiziano Barbui, MD, Ayalew Tefferi, MD, Alessandro Maria Vannucchi, MD
Journal: Blood
Blood (2014) 124 (21): 3163.
https://doi.org/10.1182/blood.V124.21.3163.3163
Published: 2014
Journal Articles

CMV~IMPACT: Results of a Randomized Controlled Trial of Immuno-Prophylactic Adoptive Cellular Therapy following Sibling Donor Allogeneic HSCT

Karl S Peggs, Eleni Tholouli, Ronjon Chakraverty, PhD, Emmanouil Nikolousis, PhD, Adrian Bloor, PhD FRCPath, Stephen Devereux, MD PhD FRCPath, Kim H. Orchard, PhD, Charles Crawley, Anne Parker, Stephen P Robinson, PhD, Frederick Chen, MDPhD, Gordon Cook, MD, Richard E Clark, MBBS MD, Kirsty Thomson, Matthew Cobb, Katy Newton, PhD, Simon Thomas, PhD, Paul Moss, PhD
Journal: Blood
Blood (2014) 124 (21): 1109.
https://doi.org/10.1182/blood.V124.21.1109.1109
Published: 2014
Journal Articles

Control Of Cytomegalovirus Reactivation Post Stem Cell Transplantation Is Mediated By Simultaneous Reconstitution Of CD4+ and CD8+ CMV-Specific T Cells

Mohammad Raeiszadeh, MPhil, Annette Pachnio, PhD, Charles Craddock, MD DPhil, Paul Moss, MD PhD, Frederick Chen, MD PhD
Journal: Blood
Blood (2013) 122 (21): 4530.
https://doi.org/10.1182/blood.V122.21.4530.4530
Published: 2013
Journal Articles

Splanchnic Vein Thrombosis Associated With Myeloproliferative Neoplasms. A Study Of The IWG-MRT In 475 Subjects

Lisa Pieri, MD, PhD, Paola Guglielmelli, PhD MD, Massimo Primignani, MD, Cecilia Brambilla, MD, Maria Luigia Randi, MD, Claudia Santarossa, MD, Mario Cazzola, MD, Elisa Rumi, MD, Francisco Cervantes, MD, PhD, Martin Ellis, MD, Frederick Chen, MD PhD, Dhiraj Tripathi, Neil Rajoriya, MD, Tiziano Barbui, MD, Federica Delaini, BiolSC, Valerio De Stefano, MD, Elena Rossi, MD, Silvia Betti, MD, Giorgina Specchia, Alessandra Ricco, Heinz Gisslinger, MD, Bettina Gisslinger, MD, Nicola Vianelli, MD, Nicola Polverelli, MD, Marco Ruggeri, MD, Francois Girodon, MD, PhD, Ayalew Tefferi, MD, Alessandro M Vannucchi, MD
Journal: Blood
Blood (2013) 122 (21): 1582.
https://doi.org/10.1182/blood.V122.21.1582.1582
Published: 2013