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Journal Articles

Proteasome Inhibitors Impair the Innate Antiviral Immune Response and Potentiate Pelareorep-Based Viral Therapy in Multiple Myeloma

Ada Dona', PhD, Domenico Viola, Enrico Caserta, PhD, Francesca Besi, PhD, James F Sanchez, PhD, Guido Marcucci, MD, Jonathan J Keats, PhD, Amrita Y. Krishnan, MD, Matt Coffey, PhD, Douglas W. Sborov, MDMSc, Gerard Nuovo, MD, Craig C Hofmeister, MDMPH, Flavia Pichiorri, PhD

Blood (2019) 134 (Supplement_1): 1816.

https://doi.org/10.1182/blood-2019-128740

Published: 2019

Journal Articles

FLT3-ITD Activates Cytoplasmic Drosha-Dependent Non-Canonical Mechanisms of Mir-155 Biogenesis in Acute Myeloid Leukemia

Le Xuan Truong Nguyen, PhD, Bin Zhang, PhD, Dinh Hoa Hoang, BS, Dandan Zhao, MD, Sergio Branciamore, Davide Maestrini, PhD, Yu-Lin SU, PhD, Sonia Rodriguez, PhD, Flavia Pichiorri, PhD, Steven Rosen, MD, Michael A. Caligiuri, MD, Stephen J. Forman, MD, Ling Li, PhD, Marcin Kortylewski, PhD, Russell Rockne, PhD, Ya-Huei Kuo, PhD, Nadia Carlesso, MD, Guido Marcucci, MD

Blood (2019) 134 (Supplement_1): 2722.

https://doi.org/10.1182/blood-2019-131871

Published: 2019

Journal Articles

First-in-Human Imaging of Multiple Myeloma Using Copper-64-Labeled Daratumumab: Preliminary Results

Blood (2019) 134 (Supplement_1): 4394.

https://doi.org/10.1182/blood-2019-126080

Published: 2019

Journal Articles

Targeting MiR-126 Blocks Progression of Myelodysplastic Syndrome and Transformation into Acute Myeloid Leukemia

Huafeng Wang, MD, Jie Sun, PhD, Dandan Zhao, MD, Hongyan Tong, Herman Wu, BS, Xia Li, PhD, Yingwan Luo, MD, Dan Dong, PhD, Tinisha McDonald, MS, Anthony Stein, MD, Monzr M. Al Malki, MD, Flavia Pichiorri, PhD, Nadia Carlesso, MD, Ya-Huei Kuo, PhD, Bin Zhang, PhD, Guido Marcucci, MD, Ling Li, PhD, Jie Jin, MD PhD

Blood (2019) 134 (Supplement_1): 1707.

https://doi.org/10.1182/blood-2019-130375

Published: 2019

Journal Articles

Oncolytics Virus Replication Using Pelareorep (Reolysin) and Carfilzomib in Relapsed Myeloma Patients Increases PD-L1 Expression with Clinical Responses

Craig C Hofmeister, MDMPH, Douglas W. Sborov, MD MS, Domenico Viola, Ada Dona, Gerald J Nuovo, PhD, Don M. Benson, Jr., MD PhD, Sagar Lonial, MD, Jonathan L Kaufman, MD, Ajay K Nooka, MD MPH, Leonard Heffner, MD, Madhav V Dhodapkar, MD, Flavia Pichiorri, PhD

Blood (2018) 132 (Supplement 1): 2655.

https://doi.org/10.1182/blood-2018-99-113500

Published: 2018

Journal Articles

Repurposing Leflunomide for Relapsed/Refractory Multiple Myeloma: Final Analysis of a Phase 1 Study

Michael Rosenzweig, Joycelynne Palmer, Ni-Chun Tsai, Ralf Buettner, PhD, Lupe Duarte, Myo Htut, Chatchada Karanes, Nitya Nathwani, MD, Flavia Pichiorri, PhD, Firoozeh Sahebi, Tim Synold, Xiwei Wu, James F Sanchez, Amrita Krishnan, MD, Stephen J Forman, Steven T Rosen

Blood (2018) 132 (Supplement 1): 2007.

https://doi.org/10.1182/blood-2018-99-120042

Published: 2018

Journal Articles

CD84: A Potential Novel Therapeutic Target in Multiple Myeloma

Emine Gulsen Gunes, PhD, Hadas Lewinsky, Domenico Viola, Enrico Caserta, Michael Rosenzweig, Myo Htut, James F Sanchez, PhD, Ralf Buettner, PhD, Guido Marcucci, Jonathan J Keats, PhD, Amrita Krishnan, MD, Steven T Rosen, Idit Shachar, Flavia Pichiorri, PhD

Blood (2018) 132 (Supplement 1): 1924.

https://doi.org/10.1182/blood-2018-99-119655

Published: 2018

Journal Articles

Downregulation of Mir-142 Promotes Leukemia Growth in Philadelphia Chromosome-Positive (Ph+) Acute Lymphoblastic Leukemia (ALL): A Possible Novel Therapeutic Target?

Blood (2018) 132 (Supplement 1): 1338.

https://doi.org/10.1182/blood-2018-99-119599

Published: 2018

Journal Articles

Immune Mediated Mechanisms of Resistance to Daratumumab

Domenico Viola, Ada Dona, Emine Gulsen Gunes, PhD, Estelle Troadec, Xiwei Wu, Sergio Branciamore, Tinisha McDonald, MS, Lucy Ghoda, PhD, Ashish Streatfield, James F Sanchez, PhD, Chatchada Karanes, Myo Htut, Michael Rosenzweig, Jonathan J Keats, PhD, Steven T Rosen, Guido Marcucci, Amrita Krishnan, MD, Flavia Pichiorri, PhD

Blood (2018) 132 (Supplement 1): 3201.

https://doi.org/10.1182/blood-2018-99-117441

Published: 2018

Journal Articles

MiR- 16 Regulates Crosstalk in NF-κB Inflammatory Signaling between Myeloma Cells and Bone Marrow Macrophages

Jihane Khalife, Domenico Viola, BS, Jayeeta Ghose, Robert Weingart, James F Sanchez, Craig C Hofmeister, MDMPH, Amrita Krishnan, MD, Guido Marcucci, MD, Nadia Carlesso, MD PhD, Enrico Caserta, PhD, Flavia Pichiorri, PhD

Blood (2017) 130 (Supplement 1): 4351.

https://doi.org/10.1182/blood.V130.Suppl_1.4351.4351

Published: 2017

Journal Articles

Copper-64-Labeled Daratumumab As a PET Imaging Tracer for Multiple Myeloma: Potential Use for Minimal Residual Disease Detection

Enrico Caserta, PhD, Junie Chea, Megan Minnix, Domenico Viola, BS, Steven Vonderfecht, Jonathan J Keats, PhD, James F Sanchez, David Colcher, John E. Shively, Amrita Krishnan, MD, Flavia Pichiorri, PhD

Blood (2017) 130 (Supplement 1): 3083.

https://doi.org/10.1182/blood.V130.Suppl_1.3083.3083

Published: 2017

Journal Articles

Repurposing Leflunomide for Relapsed/Refractory Multiple Myeloma: A Phase 1 Trial

Michael Rosenzweig, MD, Joycelynne M. Palmer, PhD, Ni-Chun Tsai, MS, Ralf Buettner, PhD, Lupe Duarte, Myo Htut, Chatchada Karanes, Nitya Nathwani, Flavia Pichiorri, PhD, Firoozeh Sahebi, George Somlo, Tim Synold, PhD, Xiwei Wu, PhD, Amrita Krishnan, MD, Stephen J. Forman, MD FACP, Steven T. Rosen, MD

Blood (2017) 130 (Supplement 1): 3144.

https://doi.org/10.1182/blood.V130.Suppl_1.3144.3144

Published: 2017

Journal Articles

Leflunomide Inhibits c-Myc Signaling and Impairs Myeloma Cell Growth

Ralf Buettner, PhD, Corey James Morales, BA, BS, Enrico Caserta, PhD, Domenico Viola, BS, Joycelynne M. Palmer, PhD, Xiwei Wu, PhD, Nagarajan Vaidehi, PhD, Hongzhi Li, PhD, Tim Synold, PhD, Amrita Krishnan, MD, Flavia Pichiorri, PhD, Michael Rosenzweig, MD, Steven T. Rosen, MD

Blood (2017) 130 (Supplement 1): 4426.

https://doi.org/10.1182/blood.V130.Suppl_1.4426.4426

Published: 2017

Journal Articles

Exploring the Possibility of Using Herpes Simplex Virus in Oncolytic Virotherapy of Multiple Myeloma

Jayeeta Ghose, Luke Russell, Enrico Caserta, Ramasamy Santhanam, Alena Cristina Jaime-Ramirez, Domenico Viola, Amrita Krishnan, Craig C Hofmeister, Balveen Kaur, Flavia Pichiorri, PhD

Blood (2016) 128 (22): 4467.

https://doi.org/10.1182/blood.V128.22.4467.4467

Published: 2016

Journal Articles

Daratumumab Impairs Myeloma Cell Adhesion Mediated Drug Resistance through CD38 Internalization

Jayeeta Ghose, Cesar Terrazas, PhD, Domenico Viola, Enrico Caserta, Amrita Krishnan, Craig C Hofmeister, Abhay Satoskar, MD PhD, Flavia Pichiorri, PhD

Blood (2016) 128 (22): 4479.

https://doi.org/10.1182/blood.V128.22.4479.4479

Published: 2016

Journal Articles

Proteomic Characterization of Circulating Extracellular Vesicles Identifies Novel Serum Myeloma Associated Markers

David Ciarlariello, Sean Harshman, Alessandro Canella, Erinn Hade, Alberto Rocci, MD, Antonio Palumbo, MD, Craig C Hofmeister, MD MPH, Michael Freitas, Don M Benson, MD PhD, Flavia Pichiorri, PhD

Blood (2015) 126 (23): 1814.

https://doi.org/10.1182/blood.V126.23.1814.1814

Published: 2015

Journal Articles

Small RNA Deep Sequencing Highlights the Important Contribution of Mirnas in Regulating IRF4/c-Myc Axis in Myeloma Development

Hanna Radomska, Alessandro Canella, Consiglio Jessica, Alberto Rocci, MD, Cascione Luciano, Hector Cordero, Liu Joseph, Enrico Caserta, Santhanam Ramasamy, Yvonne A. Efebera, MD MPH, Stefano Volinia, PhD, Craig C Hofmeister, MD MPH, Flavia Pichiorri, PhD

Blood (2015) 126 (23): 1791.

https://doi.org/10.1182/blood.V126.23.1791.1791

Published: 2015

Journal Articles

Reolysin Combined with Carfilzomib for Treatment of Relapsed Multiple Myeloma Patients

Douglas W Sborov, MD MS, Flavia Pichiorri, PhD MSC, Gerard J Nuovo, MD, Don M Benson, MD PhD, Yvonne A. Efebera, MD MPH, Ashley E Rosko, MD, Craig C Hofmeister, MD MPH

Blood (2015) 126 (23): 1835.

https://doi.org/10.1182/blood.V126.23.1835.1835

Published: 2015

Journal Articles

HDAC Inhibitor AR-42 Decreases CD44 Expression and Sensitizes Myeloma Cells to Lenalidomide

Hector Cordero-Nieves, BS, Douglas W. Sborov, MD, Alessandro Canella, MS, Zhongfa Liu, Jessica Consiglio, MS, Wenjun Ni, Emily Smith, Lara Rizzotto, PhD, Yvonne A Efebera, MD, Don M. Benson, MD PhD, Luciano Cascione, Mo Xiaokui, MS, John C. Byrd, MD, Michael R. Grever, MD, Craig C Hofmeister, MD MPH, Flavia Pichiorri, PhD

Blood (2014) 124 (21): 3377.

https://doi.org/10.1182/blood.V124.21.3377.3377

Published: 2014

Journal Articles

Circulating Mir- 16 and Mir- 25 As New Prognosticators For Multiple Myeloma

Blood (2013) 122 (21): 1853.

https://doi.org/10.1182/blood.V122.21.1853.1853

Published: 2013

NARROW

Proteasome Inhibitors Impair the Innate Antiviral Immune Response and Potentiate Pelareorep-Based Viral Therapy in Multiple Myeloma

FLT3-ITD Activates Cytoplasmic Drosha-Dependent Non-Canonical Mechanisms of Mir-155 Biogenesis in Acute Myeloid Leukemia

First-in-Human Imaging of Multiple Myeloma Using Copper-64-Labeled Daratumumab: Preliminary Results

Targeting MiR-126 Blocks Progression of Myelodysplastic Syndrome and Transformation into Acute Myeloid Leukemia

Oncolytics Virus Replication Using Pelareorep (Reolysin) and Carfilzomib in Relapsed Myeloma Patients Increases PD-L1 Expression with Clinical Responses

Repurposing Leflunomide for Relapsed/Refractory Multiple Myeloma: Final Analysis of a Phase 1 Study

CD84: A Potential Novel Therapeutic Target in Multiple Myeloma

Downregulation of Mir-142 Promotes Leukemia Growth in Philadelphia Chromosome-Positive (Ph+) Acute Lymphoblastic Leukemia (ALL): A Possible Novel Therapeutic Target?

Immune Mediated Mechanisms of Resistance to Daratumumab

MiR- 16 Regulates Crosstalk in NF-κB Inflammatory Signaling between Myeloma Cells and Bone Marrow Macrophages

Copper-64-Labeled Daratumumab As a PET Imaging Tracer for Multiple Myeloma: Potential Use for Minimal Residual Disease Detection

Repurposing Leflunomide for Relapsed/Refractory Multiple Myeloma: A Phase 1 Trial

Leflunomide Inhibits c-Myc Signaling and Impairs Myeloma Cell Growth

Exploring the Possibility of Using Herpes Simplex Virus in Oncolytic Virotherapy of Multiple Myeloma

Daratumumab Impairs Myeloma Cell Adhesion Mediated Drug Resistance through CD38 Internalization

Proteomic Characterization of Circulating Extracellular Vesicles Identifies Novel Serum Myeloma Associated Markers

Small RNA Deep Sequencing Highlights the Important Contribution of Mirnas in Regulating IRF4/c-Myc Axis in Myeloma Development

Reolysin Combined with Carfilzomib for Treatment of Relapsed Multiple Myeloma Patients

HDAC Inhibitor AR-42 Decreases CD44 Expression and Sensitizes Myeloma Cells to Lenalidomide

Circulating Mir- 16 and Mir- 25 As New Prognosticators For Multiple Myeloma

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American Society of Hematology

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ASH Publications

American Society of Hematology

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