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Journal Articles

The Translational Switch of MYC Protein Aliases in Myeloma Tumor Cells

Erming Tian, PhD MBA, Jeffery R. Sawyer, Ricky D. Edmondson, Maurizio Zangari, MD, Christopher P. Wardell, PhD MSc, BSc, Sharmilan Thanendrarajan, MD, Carolina D. Schinke, MD, Frits van Rhee, MD PhD

Blood (2019) 134 (Supplement_1): 4390.

https://doi.org/10.1182/blood-2019-131850

Published: 2019

Journal Articles

An Acquired High-Risk Chromosome Instability Phenotype in Multiple Myeloma: Jumping 1q Syndrome

Jeffery R. Sawyer, Erming Tian, PhD MBA, Brian A Walker, PhD, Christopher P. Wardell, PhD MSc, BSc, Joshua Epstein, DSc, Janet L Lukacs, Gael M. Sammartino, Clyde Bailey, Carolina D. Schinke, MD, Sharmilan Thanendrarajan, MD, Maurizio Zangari, MD, Faith E. Davies, MD, Frits van Rhee, MD PhD, Gareth Morgan, MD

Blood (2018) 132 (Supplement 1): 4489.

https://doi.org/10.1182/blood-2018-99-115090

Published: 2018

Journal Articles

Daratumamab in High Risk Relapse/Refractory Myeloma Patients Effect of 1q21 Gain and GEP70 Status

Meera Mohan, MD, Niels Weinhold, PhD, Frits van Rhee, MD PhD, Carolina D. Schinke, MD, Sharmilan Thanendrarajan, MD, Leo Rasche, MD, Jeffery R. Sawyer, Erming Tian, PhD MBA, Faith E. Davies, MD, Gareth J. Morgan, MD PhD, Maurizio Zangari, MD

Blood (2017) 130 (Supplement 1): 4373.

https://doi.org/10.1182/blood.V130.Suppl_1.4373.4373

Published: 2017

Journal Articles

MYC Rearrangements in Multiple Myeloma Are Complex, Can Involve More Than Five Different Chromosomes, and Correlate with Increased Expression of MYC and a Distinct Downstream Gene Expression Pattern

Aneta Mikulasova, PhD, Cody Cody Ashby, PhD, Ruslana G. Tytarenko, MS, Michael Bauer, PhD, Konstantimos Mavrommatis, PhD, Christopher P. Wardell, PhD, Matthew Trotter, PhD, Shayu Deshpande, Owen W. Stephens, Erming Tian, PhD MBA, Graham Jackson, Faith E. Davies, MD, Anjan Thakurta, PhD, Nikhil Munshi, MD, Gareth J. Morgan, MD PhD, Brian A Walker, PhD

Blood (2017) 130 (Supplement 1): 65.

https://doi.org/10.1182/blood.V130.Suppl_1.65.65

Published: 2017

Journal Articles

Chromosome 1q12 Instability Drives Both 1q21 Amplification and Arm-Length Deletions in Multiple Myeloma

Jeffery R. Sawyer, Erming Tian, PhD MBA, Brian A Walker, PhD, Charles M. Swanson, Janet L Lukacs, Gael M. Sammartino, Clyde Bailey, Sharmilan Thanendrarajan, MD, Carolina D. Schinke, MD, Maurizio Zangari, MD, Frits van Rhee, MD PhD, Faith E. Davies, MD, Gareth J. Morgan, MD PhD

Blood (2017) 130 (Supplement 1): 3060.

https://doi.org/10.1182/blood.V130.Suppl_1.3060.3060

Published: 2017

Journal Articles

Translocations and Jumping Rearrangements at 8q24 Result in over-Expression of MYC and are Key Drivers of Disease Progression

Erming Tian, PhD, Jeffery Sawyer, Owen W Stephens, Ruslana Tytarenko, Sharmilan Thanendrarajan, MD, Carolina Schinke, MD, Maurizio Zangari, MD, Frits van Rhee, MD PhD, Faith E Davies, MD, Brian A Walker, PhD, Gareth J Morgan, MD PhD

Blood (2016) 128 (22): 115.

https://doi.org/10.1182/blood.V128.22.115.115

Published: 2016

Journal Articles

Concurrent Amplification of MYC and 1q21 in Multiple Myeloma: Focal and Segmental Jumping Translocations of MYC

Jeffery Sawyer, Erming Tian, PhD, Brian A Walker, PhD, Niels Weinhold, PhD, Charles Swanson, Janet L Lukacs, Regina Binz, Gael Sammartino, Sharmilan Thanendrarajan, MD, Carolina Schinke, MD, Maurizio Zangari, MD, Faith E Davies, MD, Frits van Rhee, MD PhD, Gareth J Morgan, MD PhD

Blood (2016) 128 (22): 3266.

https://doi.org/10.1182/blood.V128.22.3266.3266

Published: 2016

Journal Articles

Deletion of TP53 (17p13) Is Associated with Poor Outcome for Newly Diagnosed High-Risk Multiple Myeloma

Erming Tian, PhD, Joshua Epstein, DSc, Pingping Qu, PhD, Christoph Heuck, MD, Frits van Rhee, MD PhD, Maurizio Zangari, MD, Antje Hoering, Jeffery Sawyer, Bart Barlogie, MD PhD, Gareth J Morgan, MDPhD

Blood (2015) 126 (23): 2982.

https://doi.org/10.1182/blood.V126.23.2982.2982

Published: 2015

Journal Articles

Expression and in Vitro Binding of Protease Activated Receptor1 (PAR1) with Novel Anti-PAR1 Molecules: Data on Fresh Myeloma Marrow Plasma Cells and Human Myeloma Cell Lines

Meral Beksac, MD, Pinar Ataca, MD, Berna Atesagaoglu, MD, Klara Dalva, Andry Nur Hidayat, Ismail Yalcin, Esin Yalcin Aki, Tulin Ozkan, Xenofon Papanikalaou, Saad Z Usmani, MD FACP, Erming Tian, PhD

Blood (2015) 126 (23): 4440.

https://doi.org/10.1182/blood.V126.23.4440.4440

Published: 2015

Journal Articles

Defining Risk of MGUS and AMM Progression to Myeloma By Ig Heavy-Chain FISH

Erming Tian, PhD, Pingping Qu, PhD, Caleb K Stein, MS, Gareth J Morgan, MD PhD, Bart Barlogie, MD, PhD, Joshua Epstein, DSc

Blood (2014) 124 (21): 3408.

https://doi.org/10.1182/blood.V124.21.3408.3408

Published: 2014

Journal Articles

Evidence of an Epigenetic Origin for High-Risk 1q21 Copy Number Aberrations in Multiple Myeloma

Jeffrey Sawyer, PhD, Erming Tian, PhD, Christoph Heuck, MD, Donald Johann, MD MS, Joshua Epstein, DSc, Charles Swanson, Janet Lukacs, Regina Lichti Binz, Gael Sammartino, Maurizio Zangari, MD, Frits van Rhee, MD PhD, Bart Barlogie, MD, PhD

Blood (2014) 124 (21): 725.

https://doi.org/10.1182/blood.V124.21.725.725

Published: 2014

Journal Articles

The Antimalarial Agent Artesunate Exerts Its Antimyeloma Activity By Affecting The Mitochondria and The Reactive Oxygen Status Of The Myeloma Cells and Its Efficacy Depends On Intracellular Bivalent Iron Levels

Xenofon Papanikolaou, MD, Sarah K. Johnson, PhD, Tarun K. Garg, PhD, Erming Tian, PhD, Ruslana Tytarenko, Bart Barlogie, MD, PhD, Joshua Epstein, DSc, Christoph Heuck, MD

Blood (2013) 122 (21): 4444.

https://doi.org/10.1182/blood.V122.21.4444.4444

Published: 2013

Journal Articles

Cytogenetic Features Of Patients With Monoclonal Gammopathy Of Undetermined Significance (MGUS) and Asymptomatic Multiple Myeloma (AMM)

Erming Tian, PhD, Sarah Waheed, MD, Jeffrey Sawyer, PhD, Qing Zhang, PhD, Christoph Heuck, MD, Madhav V. Dhodapkar, MD, Bart Barlogie, MD, PhD, Joshua Epstein, DSc

Blood (2013) 122 (21): 3108.

https://doi.org/10.1182/blood.V122.21.3108.3108

Published: 2013

Journal Articles

An Inborn Variation In The Anaplastic Lymphoma Receptor Tyrosine Kinase Gene ( ALK ) Increases Risk Of MAF (Musculoaponeurotic Fibrosarcoma Oncogene Homolog) High Expressing Myeloma

Annette Juul Vangsted, MD, Stephen Erickson, Ph.D, Naveen Sanath Kumar, MD, Elizabeth Ann Coleman, PhD, Erming Tian, PhD, Julia Goodwin, PhD, Joshua Epstein, DSc, Owen Stephens, Ph.D., Bart Barlogie, MD, PhD, Christoph Heuck, MD

Blood (2013) 122 (21): 1908.

https://doi.org/10.1182/blood.V122.21.1908.1908

Published: 2013

Journal Articles

Prediction of Cytogenetic Abnormalities in Multiple Myeloma Based on Gene Expression Profiles

Yiming Zhou, PhD, Qing Zhang, PhD, Christoph Heuck, MD, Owen Stephens, Erming Tian, PhD, Jeffrey Sawyer, PhD, Marie-Astrid Cartron-Mizeracki, MS, Bart Barlogie, MD, PhD, John D Shaughnessy, Jr., PhD

Blood (2011) 118 (21): 629.

https://doi.org/10.1182/blood.V118.21.629.629

Published: 2011

Journal Articles

Jumping Translocations 1q12 Contribute to Copy Number (CN) Alterations in Multiple Myeloma (MM): Unexpected Focal Amplifications of Receptor Chromosomes (RC)

Jeffrey Sawyer, Erming Tian, PhD, John D. Shaughnessy, Jr., PhD, Janet Lukacs, Regina Lichti Binz, Edward Thomas, Gael Sammartino, Charles Swanson, Christoph Heuck, MD, Yazan Alsayed, MD, Elias J. Anaissie, MD, Bijay Nair, MD, Sarah Waheed, MD, Saad Usmani, MD, FACP, Frits van Rhee, MD, PhD, Bart Barlogie, MD, Ph.D

Blood (2011) 118 (21): 298.

https://doi.org/10.1182/blood.V118.21.298.298

Published: 2011

Journal Articles

Thrombin-Induced PARI Signaling Pathway Modulates ß-Catenin in the Transformation of Symptomatic Myeloma Cells Into the Quiescent Phenotype,

Erming Tian, PhD, Saad Usmani, MD, FACP, Yiming Zhou, PhD, Bart Barlogie, MD, Ph.D, John D Shaughnessy, Jr., PhD

Blood (2011) 118 (21): 3932.

https://doi.org/10.1182/blood.V118.21.3932.3932

Published: 2011

Journal Articles

DKK1 is an Immediate Early Gene in Multiple Myeloma Cells Modulated by Cell Density and IL-6

Erming Tian, PhD, Yawei Qiang, MD, PhD, Bart Barlogie, MD, PhD, John Shaughnessy, Jr, PhD

Blood (2010) 116 (21): 1928.

https://doi.org/10.1182/blood.V116.21.1928.1928

Published: 2010

Journal Articles

Integration of DNA Copy Number and Gene Expression Alterations Reveal Novel Insights into the Molecular Pathogenesis and Prognosis of Multiple Myeloma

Yiming Zhou, PhD, Bart Barlogie, MD, PhD, Damir Herman, PhD, Owen Stephens, PhD, Erming Tian, PhD, David Williams, PhD, Marie-astrid Cartron, PhD, Frits van Rhee, MD, PhD, Mauricio Pineda-Roman, MD, PhD, Yazan Alsayed, MD, PhD, Elias Anaissie, MD, PhD, Jeffrey Sawyer, Ph.D., John D. Shaughnessy, Jr., PhD

Blood (2008) 112 (11): 250.

https://doi.org/10.1182/blood.V112.11.250.250

Published: 2008

NARROW

The Translational Switch of MYC Protein Aliases in Myeloma Tumor Cells

An Acquired High-Risk Chromosome Instability Phenotype in Multiple Myeloma: Jumping 1q Syndrome

Daratumamab in High Risk Relapse/Refractory Myeloma Patients Effect of 1q21 Gain and GEP70 Status

MYC Rearrangements in Multiple Myeloma Are Complex, Can Involve More Than Five Different Chromosomes, and Correlate with Increased Expression of MYC and a Distinct Downstream Gene Expression Pattern

Chromosome 1q12 Instability Drives Both 1q21 Amplification and Arm-Length Deletions in Multiple Myeloma

Translocations and Jumping Rearrangements at 8q24 Result in over-Expression of MYC and are Key Drivers of Disease Progression

Concurrent Amplification of MYC and 1q21 in Multiple Myeloma: Focal and Segmental Jumping Translocations of MYC

Deletion of TP53 (17p13) Is Associated with Poor Outcome for Newly Diagnosed High-Risk Multiple Myeloma

Expression and in Vitro Binding of Protease Activated Receptor1 (PAR1) with Novel Anti-PAR1 Molecules: Data on Fresh Myeloma Marrow Plasma Cells and Human Myeloma Cell Lines

Defining Risk of MGUS and AMM Progression to Myeloma By Ig Heavy-Chain FISH

Evidence of an Epigenetic Origin for High-Risk 1q21 Copy Number Aberrations in Multiple Myeloma

The Antimalarial Agent Artesunate Exerts Its Antimyeloma Activity By Affecting The Mitochondria and The Reactive Oxygen Status Of The Myeloma Cells and Its Efficacy Depends On Intracellular Bivalent Iron Levels

Cytogenetic Features Of Patients With Monoclonal Gammopathy Of Undetermined Significance (MGUS) and Asymptomatic Multiple Myeloma (AMM)

An Inborn Variation In The Anaplastic Lymphoma Receptor Tyrosine Kinase Gene ( ALK ) Increases Risk Of MAF (Musculoaponeurotic Fibrosarcoma Oncogene Homolog) High Expressing Myeloma

Prediction of Cytogenetic Abnormalities in Multiple Myeloma Based on Gene Expression Profiles

Jumping Translocations 1q12 Contribute to Copy Number (CN) Alterations in Multiple Myeloma (MM): Unexpected Focal Amplifications of Receptor Chromosomes (RC)

Thrombin-Induced PARI Signaling Pathway Modulates ß-Catenin in the Transformation of Symptomatic Myeloma Cells Into the Quiescent Phenotype,

DKK1 is an Immediate Early Gene in Multiple Myeloma Cells Modulated by Cell Density and IL-6

Integration of DNA Copy Number and Gene Expression Alterations Reveal Novel Insights into the Molecular Pathogenesis and Prognosis of Multiple Myeloma

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American Society of Hematology

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American Society of Hematology

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